CAS: 505-29-3; 1,4-Dithiane

该化合物是一种循环有机化合物,分子式为C4H8S2,由六人环组成,在对立位置上含有两个硫原子,这种结构具有独特的化学特性,使其成为有机合成的宝贵中间体,特别是在准备含有硫的外生循环和电离层以协调化学方面,它的稳定性和作为牵引剂的离子和提高其在金属复合和催化应用中的效用的能力.此外,1,4-二丁烷是硫代金属和其他硫化化合物合成的前体,其高纯度和一贯性能使它成为研究和工业应用的可靠选择,需要精确的硫化合物结合.

结构式图片

相似化合物

55704-78-4 175136-94-4 15980-17-3

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号540-63-6 1,2-乙二硫醇 | CAS号107-06-2 1,2-二氯乙烷 | CAS号106-93-4 1,2-二溴乙烷 | CAS号25423-55-6 2-[2-(2-sulfany... | CAS号3563-36-8 1,2-二乙烷 | CAS号113322-95-5 | CAS号2001-45-8 四苯基氯化膦 | CAS号505-60-2 芥子气 | CAS号50-00-0 甲醛 | CAS号2040-67-7 trans-2,3-Dichl... | CAS号19087-70-8 1,4-dithiane 1-oxide | CAS号505-60-2 芥子气 | CAS号89124-42-5 1,4-dithiane 1,... | CAS号33976-40-8 1,4-dithiane 1,... | CAS号679-77-6 Bis(pentafluoro...

合成工艺路线路线简述

  • 合成目标产物 1,4-Dithiane 主要起始原料 Mustard Gas
  • (文献来源)合成步骤主要原料 Mustard Gas
硫二甘醇置于aluminum Oxide体系中,化学反应生成 1,4-二噻烷
参考文献:Jur'Ew Et Al.,Doklady Akademii Nauk Sssr,1949,Vol. 68,P. 717,718
标题:Jur'Ew Et Al.,Doklady Akademii Nauk Sssr,1949,Vol. 68,P. 717,718

海关参考信息

专利信息


专利号:US-9920084-B2
优先权日:2011-08-23
标题 :Ionic tags for synthesis of oligoribonucleotides
发明人:DAMHA MASAD J; HASSLER MATTHEW; CHAN TAK-HANG; NANDYALA MALLIKARJUNA REDDY; DONGA ROBERT ALEXANDER
权利人:DAMHA MASAD J; HASSLER MATTHEW; CHAN TAK HANG; NANDYALA MALLIKARJUNA REDDY; DONGA ROBERT ALEXANDER; THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV; HONG KONG POLYTECHNIC UNIV
摘要:The invention relates to the chemical synthesis of oligonucleotides, e.g., oligoribonucleotides. In another aspect, the invention relates to compounds of formula (II) processes for making these compounds, and the use thereof in the chemical synthesis of oligonucleotides, e.g., oligoribonucleotides. The invention also relates to methods of synthesis of oligomers, including but not limited to oligopeptides, oligosaccharides and oligonucleotides, particularly oligoribonucleotides and also oligodeoxyribonucleotides, in solution systems, and ionic tag linkers for use in methods provided herein.

专利号:US-12421534-B2
优先权日:2021-11-10
标 题 :Engineered enzymes and method for the synthesis of diverse tyrosine analogs
发明人:ALMHJELL PATRICK J; ARNOLD FRANCES H
权利人:CALIFORNIA INST OF TECHN
摘要:Provided herein is an engineered tryptophan synthase β-subunit (TrpB) that catalyzes the synthesis of tyrosine, tyrosine analogs, or salts thereof. Also provided herein are methods for preparing tyrosine, tyrosine analogs, or a salt thereof using the engineered TrpB described herein.

专利号:US-11548898-B2
优先权日:2017-07-06
标题 :Synthesis of halichondrins
发明人:KISHI YOSHITO; AI YANRAN; YE NING; WANG QIAOYI; YAHATA KENZO; ISO Kentaro; NAINI SANTHOSH REDDY; YAMASHITA SHUJI; LEE JIHOON; OHASHI ISAO; FUKUYAMA TAKASHI
权利人:HARVARD COLLEGE; EISAI R&D MAN CO LTD
摘要:The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A).

专利号:US-7825244-B2
优先权日:2005-06-10
标题:Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
发明人:BAINDUR NAND; GAUL MICHAEL DAVID; KREUTTER KEVIN DOUGLAS; XU GUOZHANG
权利人:JANSSEN PHARMACEUTICA NV
摘要:The invention is directed to alkylquinoline and alkylquinazoline compounds of Formula C: n nwherein R 1 , R 2 , R 99 , and X are as defined herein, the use of such compounds in the synthesis of protein tyrosine kinase inhibitors, particularly inhibitors of FLT3 and/or c-kit and/or TrkB.

专利号:US-2012302756-A1
优先权日:2010-02-19
标 题 :Process for synthesis of 2-substituted pyrrolidines and piperadines
发明人:LELETI RAJENDER REDDY; LIU YUGANG; PRASHAD MAHAVIR
权利人:LELETI RAJENDER REDDY; LIU YUGANG; PRASHAD MAHAVIR
摘要:The present invention provides a highly efficient, versatile one-step process for asymmetric synthesis of either diastereomer of 2-substituted pyrrolidines from a single starting material with excellent yields and high diastereoselectivety. Also provided is a method for the asymmetric synthesis of both diastereomers of 2-substituted piperidines with good yields and excellent diastereoselectivety. Diasteroselectivity is controlled effectively by choice of reducing agent.

专利号:US-4182719-A
优先权日:1977-05-17
标题 :Synthesis of optically active vitamin E
发明人:COHEN NOAL; SAUCY GABRIEL
权利人:HOFFMANN LA ROCHE
摘要:Synthesis of optically active vitamin E from 2-methyl-5-oxotetrahydro-2-furoic acid including intermediates in this synthesis.
河北信源科技有限公司
⚠️ 未注册 · 未认证企业
⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
数据来源于公开网络搜索,平台未作核实,请自行辨别。
🏢敬请 企业认领
🏬开设公司展台
📢获取免费会员权益
🎖️点亮专属注册企业标签
📇展现公司完整信息 样本查看立即注册认领 →
网址: http://www.xinyuan-chem.cn
企业联系电话:010-68418738👤
📞河北信源科技有限公司 ⚠️参考联系方式
联系人:贾经理
电话:010-68418738

传真:QQ:3007974312
邮箱:sales@xinyuan-chem.cn
通信地址: 河北省石家庄市辛集市新城镇高新区
邮编:
🆔 联系时候可告知是从"百琢研"平台获取的信息.
⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

地址:河北省石家庄市辛集市新城镇高新区
⚠️ 未注册 · 未认证企业
注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别
✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
南京大唐医药科技有限公司
⚠️ 未注册 · 未认证企业
⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
数据来源于公开网络搜索,平台未作核实,请自行辨别。
🏢敬请 企业认领
🏬开设公司展台
📢获取免费会员权益
🎖️点亮专属注册企业标签
📇展现公司完整信息 样本查看立即注册认领 →
网址: http://www.datangpharmatech.com
电话: 025-84341491👤
📞南京大唐医药科技有限公司 ⚠️参考联系方式

销售电话:025-84341491
邮箱:821832400@qq.com
🆔 联系时候可告知是从"百琢研"平台获取的信息.
⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

⚠️ 未注册 · 未认证企业
注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别 ✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
第 1 / 1 页
现货

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

[参考文献]: H Lee, Et Al. Genotoxicity Of 1,3-Dithiane And 1,4-Dithiane In The Cho/sce Assay And The Salmonella/microsomal Test. Mutat Res. 1994 Jun;321(4):213-8.

合成参考文献


摘要:NIOSH; International Safety Cards. 1,4-Dithiane. 505-29-3. Available at:
摘要:Franke C et al; Chemosphere 29: 1501-14 (1994)
摘要:Sokolovs, I.; Suna, E., Science of Synthesis: Hypervalent Halogens in Organic Synthesis, (2025) .
参考文献:10.1021/jo060780f
摘要:Valiulin RA, Kottani R, Kutateladze AG. When ethyl is infinitely different from methyl: double addition of lithiated dithianes to aromatic carboxylates revisited. J Org Chem. 2006 Jun 23;71(13):5047–9. doi: 10.1021/jo060780f.
📝 需求与反馈
尽可能描述清楚需求与问题信息
×

通知