CAS: 54-06-8; 3-Hydroxy-1-Methyl-5,6-Indolinedione

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CAS号329-65-7 DL-肾上腺素(肾上腺素) | CAS号51-43-4 肾上腺素 | CAS号672-73-1 4-[1-Hydroxy-2-...

肾上腺素置于双氧水,Sodium Sulfate体系中,化学反应生成 肾上腺素红
参考文献:使用基于多两性电解质的新型钴配合物活化H2O 2并产生超氧化物
标题:使用基于多两性电解质的新型钴配合物活化H2O 2并产生超氧化物
摘要:通过对co(II)的吸收,固态NMR和能量色散x射线分析的平衡研究,表征了一种基于co(II)和具有聚两性电解质性质的水凝胶的新型催化剂.源自甲基丙烯酸和2-甲基咪唑的基质易于通过一站式策略合成,并将配位性能与耐化学性相结合.通过电子自旋共振研究了该材料对H2O 2活化的催化活性,证实了超氧自由基的释放.相互作用的可能机制涉及同时产生双氧,质子和水.在H2O 2活化中评估催化性能用于氧化两种与环境有关的代表性有机化合物.通过用60 Mm的H2O 2氧化并吸附在催化剂上,在2小时内从蒸馏水中去除了约70%的甲基橙(一种偶氮染料).在0.1 M Na 2 So 4的存在下,染料的吸附量最小.该过程的动力学遵循伪一级经验模型,催化剂被回收再利用.选择肾上腺素作为易受超氧化物攻击的药物模型.遵循拟一级动力学模型,在不到6分钟的时间内即可达到约80%的肾上腺色素转化率.
DOI:10.1016/j.Apcata.2013.08.002

专利信息

专利号:WO-2022081040-A1
优先权日:2020-10-14
标题:Method for synthesizing poly-1,4-ethylenepiperazine and a copolymer of n-oxidized 1,4-ethylenepiperazine and (n-carboxymethyl)-1,4-ethylenepiperazinium bromide and their derivatives
发明人：TITENOK KONSTANTIN VIKTOROVICH
权利人:LLC NPO PETROVAX PHARM
摘要:The invention relates to the field of chemistry and technology for the organic synthesis of high molecular weight compounds, and more particularly to a polymerization reactor and to methods for producing high purity poly-1,4-ethylenepiperazine (PEP) and its derivatives with a narrow molecular weight distribution, and also to methods for producing a copolymer of N-oxidized 1,4-ethylenepiperazine and (N-carboxymethyl)-1,4-ethylenepiperazinium bromide and its derivatives, as well as to the products obtained using said methods. The products of the proposed methods, in particular, a copolymer of N-oxidized 1,4-ethylenepiperazine and (N-carboxymethyl)-1,4-ethylenepiperazinium bromide (with two units) and a copolymer of N-oxidized 1,4-ethylenepiperazine, (N-carboxymethyl)-1,4-ethylenepiperazinium bromide and 1,4-ethylenepiperazine, the structure of which contains a third unit with unsubstituted nitrogen atoms, are more stable throughout their entire shelf life, exhibit improved pharmacological properties by comparison with a copolymer produced using prior art technology, and can be used as a conjugate platform for creating prolonged-release drugs based on therapeutic proteins (cytokines, enzymes, hormones, growth factors, monoclonal antibodies). They can also be used as an adjuvant in different vaccines and for producing conjugates and complexes with antigens for boosting immune response.

专利号:US-5512577-A
优先权日:1994-06-02
标 题:Bicyclic hexahydroaporphine and 1-benzyloctahydroisoquinoline therapeutic compositions and processes for utilizing said compositions
发明人：ROCHE VICTORIA F; OHIA S EDET; ROCHE EDWARD B
权利人:UNIV CREIGHTON
摘要:The invention relates to the method of synthesis of bicyclic hexahydroaporphine compounds which may provide improved therapy for diseases characterized by an increase in intraocular pressure. More specifically, the present invention relates to the preparation of agents which may provide for improved treatment of patients with glaucoma or ocular hypertension. The present invention describes the intraocular pressure lowering capabilities of several of the bicyclic hexahydroaporphine structures.

专利号:RU-2017739-C1
优先权日:1989-12-15
标 题 :Method of synthesis of 2-substituted 4-(3-tert -butyl-4-hydroxyphenyl)thiazoles

专利号:ES-224060-A1
优先权日:1955-09-21
标题 :PROCEDURE FOR QUICK SYNTHESIS OF SEMICARBAZONE OF ADRENOCROME AND ITS DERIVATIVES

专利号:JP-S52118467-A
优先权日:1976-03-31
标题 :Synthesis of adrenochrome derivatives

专利号:JP-S52118466-A
优先权日:1976-03-31
标题 :Synthesis of adrenochrome