CAS: 39186-58-8; 4-Bromo-2,2-Diphenylbutyronitrile

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二苯乙腈置于sodium Amide,苯体系中,化学反应生成溴乙基二苯乙腈
参考文献:Bockmuehl; Ehrhart,Justus Liebigs Annalen Der Chemie,1949,Vol. 561,P. 52,76
标题:Bockmuehl; Ehrhart,Justus Liebigs Annalen Der Chemie,1949,Vol. 561,P. 52,76

专利信息

专利号:US-5302595-A
优先权日:1988-10-04
标题:Muscarinic receptor antagonists
发明人：CROSS PETER E; MACKENZIE ALEXANDER R
权利人:PFIZER
摘要:Compounds of the formula I ##STR1## wherein X, Y and v are as defined below, novel intermediates used in their synthesis, and the pharmaceutically acceptable salts of such compounds and intermediates. The compounds of formula I and the novel intermediates used in their synthesis are muscarinic receptor antagonists that are selected for smooth muscle muscarinic sites and are useful in the prevention and treatment of diseases associated with altered motility or tone of smooth muscle, such as irritable bowel syndrome, diverticular disease, urinary incontinence, aesophageal achalasia, and chronic obstructive airways disease.

专利号:US-11535647-B2
优先权日:2018-09-14
标题 :Peptide purification method using sulfonate compound
发明人：MATSUYAMA KEISUKE; YAMAMOTO KENICHIRO; MURAKAMI SAYOKO
权利人:NAGASE & CO LTD
摘要:A method for purifying a target peptide may include mixing a peptide product obtained through a peptide synthesis with a solvent in the presence of a sulfonic acid compound to obtain a solid; and performing a solid-liquid separation to collect the solid.