专利号:US-3950416-A 优先权日:1967-11-24 标题 :Synthesis of dicyanoformamides 发明人:PATTON TAD L 权利人:EXXON RESEARCH ENGINEERING CO 摘要:Dicyanoformamides having aromatic moieties as novel composition of matter are prepared by the reaction of a diisocyanate having an aromatic moiety with two (2) moles of hydrogen cyanide in the presence of a specially defined, hindered catalyst which will not promote further polymerization.
专利号:US-RE42890-E 优先权日:2003-05-23 标题 :Furazanobenzimidazoles 发明人:EBERLE MARTIN; BACHMANN FELIX; STREBEL ALESSANDRO; ROY SUBHO; SRIVASTAVA SUDHIR; SAHA GOUTAM 权利人:BASILEA PHARMACEUTICA AG 摘要:The invention relates to compounds of formula (I) wherein R represents aryl or heteroaryl, X is oxygen, a carbonyl group, an oxime derivative of a carbonyl group or an α,β-unsaturated carbonyl group, and the substituents R 1 to R 6 have the meanings given in the specification, for use as medicaments, to novel compounds of formula (I), to methods of synthesis of such compounds, to pharmaceutical compositions containing compounds of formula (I), to the use of a compounds of formula (I) for the preparation of a pharmaceutical composition for the treatment of neoplastic and autoimmune diseases, and to methods of treatment of neoplastic and autoimmune diseases using such compounds of formula (I) or of pharmaceutical compositions containing same
专利号:US-7858600-B2 优先权日:2000-03-31 标 题 :7- and 9- carbamate, urea, thiourea, thiocarbamate, and heteroaryl-amino substituted tetracycline compounds 发明人:NELSON MARK L; LEVY STUART B; FRECHETTE ROGER; BOWSER TODD; ISMAIL MOHAMED Y 权利人:PARATEK PHARM INNC; TUFTS COLLEGE 摘要:Substituted tetracycline compounds, methods of synthesis, and methods of use are discussed. Tetracyclines useful for treating tetracycline related disorders are also discussed. Intermediates useful for synthesizing other tetracycline compounds are also included.
参考标题:Homogeneous Catalytic Hydrogenation Of Amides To Amines 作者:Jacorien Coetzee,Deborah L. Dodds,Jürgen Klankermayer,Sandra Brosinski,Walter Leitner,Alexandra M. Z. Slawin,David J. Cole-Hamilton |发布日期:2013.8.12 摘要:Hydrogenation Of Amides In The Presence Of [ru(Acac)3] (Acach=2,4‐pentanedione), Triphos [1,1,1‐tris‐ (Diphenylphosphinomethyl)Ethane] And Methanesulfonic Acid (Msa) Produces Secondary And Tertiary Amines With Selectivities As High As 93 % Provided That There Is At Least One Aromatic Ring On N. The System Is Also Active For The Synthesis Of Primary Amines. In An Attempt To Probe The Role Of Msa And
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摘要:N. F. Hall and M. R. Sprinkle. J. Am. Chem. Soc. 54, 3469 (1932). 摘要:F. Aufauvre, M. Dantonnet and M.L. Dondon. Bull. Soc. Chim. France 1965, 3566.