CAS: 138-15-8; (S)-2-Aminopentanedioic Acid Hydrochloride

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L-谷氨酸置于盐酸体系中,用 水 用作溶剂,化学反应 0.25H,反应生成L-谷氨酸盐酸盐
参考文献:Lysine Isotopologues,Compositions Comprising The Same And Methods Of Synthesis
标题:Lysine Isotopologues,Compositions Comprising The Same And Methods Of Synthesis
摘要:本发明涉及如本文所述的赖氨酸同位素异构体i和1-A的式子,以及合成这些同位素异构体及其衍生物和中间体的方法.在一个方面,本文描述了一种化学化合物,其包含一个同位素标记的类似物,即标准或天然存在的赖氨酸的同位素异构体.该赖氨酸同位素异构体是通过合成方法形成的,其中稳定元素同位素被整合到选定位置.因此,该赖氨酸同位素异构体的分子质量与标准或天然存在的赖氨酸的质量不同.

专利信息

专利号:US-2012282652-A1
优先权日:2011-02-28
标题 :Preparation of peptide mixtures by protease catalysis designed to provide useful biological and physical properties
发明人：GROSS RICHARD A; VISWANATHAN KODANDARAMAN; QIN XU
权利人:GROSS RICHARD A; VISWANATHAN KODANDARAMAN; QIN XU; POLITECHNIC INST UNIV NEW YORK
摘要:A process for preparing unique peptide mixtures with a broad range of uses using combinations of natural and non-natural amino acid alkyl ester monomers and specific combinations of these monomers as dimers, trimers and higher oligomers selected from the large group of structural motifs that lead to useful physical and/or biological properties and that have been or may be identified from solid state peptide synthesis, isolation of peptides from natural sources, and production of peptides by recombinant DNA methods, or identification of peptides by recombinant methods such as phage display, the method of peptide synthesis comprising a) admixing one or more natural and non-natural amino acid alkyl ester monomer, dimer, trimer and higher oligomers with one or more proteases in a reaction medium; b) heating the mixture to between about 5° C. to about 90° C. for between 5 minutes and 24 hours; and c) recovering the formed oligopeptide.

专利号:US-9840457-B2
优先权日:2013-03-15
标题 :Lysine isotopologues, compositions comprising the same and methods of synthesis
发明人：BRADLEY JOEL CHANDLER; WOOD WILLIAM WAKEFIELD; BARKALLAH SALIM; RYAN WILLIAM JAMES; TITMAS RICHARD CHARLES; SCHWINDEN MARK DONALD; KOZAK JANUSZ KONRAD; ELMASRI MARWAN; TORKELSON STEVEN MICHAEL
权利人:CAMBRIDGE ISOTOPE LABORATORIES INC
摘要:This invention relates to lysine isotopologues of Formulas I and 1-A, as described herein, and processes for synthesizing the same and derivatives and intermediates involved therein. In one aspect, described herein is a chemical compound comprising an isotopically labeled analog, i.e., an isotopologue of a standard or naturally occurring lysine. The lysine isotopologue is synthetically formed to have stable isotopes of elements incorporated at selected positions. As such, the lysine isotopologue has a molecular mass different from the mass of a standard or naturally occurring lysine.

专利号:US-8530405-B2
优先权日:2010-10-04
标题:Method of preparing water-soluble and biodegradable antimicrobial agent
发明人：LI CHUN-YI; CHANG KEN-YUAN; LIU CHIA-CHANG; TSAI YING-NAN
权利人:LI CHUN-YI; CHANG KEN-YUAN; LIU CHIA-CHANG; TSAI YING-NAN; FAR EASTERN NEW CENTURY CORP
摘要:A method of preparing a water-soluble and biodegradable antimicrobial agent is provided. The method includes treating a polypeptide compound with sodium hypochlorite for at least 1 min, such that the polypeptide compound has at least one N-halamine group and has good antimicrobial effect. By using the method of the present invention, a chemical synthesis process is not required and an organic solvent is not required either, and thus, an antimicrobial agent having high water solubility, biodegradability, non-toxicity, good sterilization effect, and regeneration can be prepared with reduced harms to the environment.

专利号:WO-2004113337-A1
优先权日:2003-06-25
标 题:Convergent synthesis of a garft inhibitor containing a methyl substitute thiophene core and a tetrahydropyrido`2,3-d! pyrimidine ring system and intermediates therefor

专利号:CN-102344452-A
优先权日:2010-07-22
标 题 :A new method for the synthesis of pemetrexed disodium salt

专利号:US-2016016890-A1
优先权日:2013-03-15
标题:Lysine isotopologues, compositions comprising the same and methods of synthesis