专利号:US-8471006-B2 优先权日:2003-10-31 标题:Coupling agents for peptide synthesis 发明人:CARPINO LOUIS A; XIA JUSONG; ZHANG CHONGWU; SFERDEAN CALIN DAN 权利人:CARPINO LOUIS A; XIA JUSONG; ZHANG CHONGWU; SFERDEAN CALIN DAN; UNIV MASSACHUSETTS 摘要:The present invention is directed to compounds of the formula: n nor salts thereof or N-oxides and their use in peptide synthesis.
专利号:US-7468375-B2 优先权日:2004-04-26 标题:Inhibitors of the HIV integrase enzyme 发明人:DRESS KLAUS RUPRECHT; HU QIYUE; JOHNSON TED WILLIAM; PLEWE MICHAEL BRUNO; TANIS STEVEN PAUL; WANG HAI; YANG ANLE; YIN CHUNFENG; ZHANG JUNHU 权利人:PFIZER 摘要:The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIVâ€?) integrase enzyme.
专利号:CN-111100068-A 优先权日:2019-12-29 标 题 :A kind of method for fast and efficient synthesis of methyl 3-aminoisonicotinate
专利号:US-7122549-B2 优先权日:2000-11-03 标题:Saframycins, analogues and uses thereof 发明人:MYERS ANDREW G; PLOWRIGHT ALLEYN T 权利人:HARVARD COLLEGE 摘要:In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel compounds of general formula (I), and methods for the synthesis thereof. n n n n n n n n n n In another aspect, the present invention provides pharmaceutical compositions comprising a compound of formula (I) and a pharmaceutically acceptable carrier. In yet another aspect, the present invention provides methods for treating cancer comprising administering a therapeutically effective amount of a compound of formula (I) to a subject in need thereof.
参考标题:Zinc-Catalyzed Selective Reduction Of Cyclic Imides With Hydrosilanes: Synthesis Of ω-Hydroxylactams 作者:Guangni Ding,Bin Lu,Yuyuan Li,Jun Wan,Zhaoguo Zhang,Xiaomin Xie |发布日期:2015.3.23 摘要:Cyclic Imides Were Selectively Reduced To The Corresponding ω‐hydroxylactams In High Yields With (Eto)3Sih (Triethoxysilane) Or Pmhs (Polymethylhydrosiloxane) Under Catalysis Of Zinc Diacetate Dehydrate [zn(Oac)2⋅2 H2O] (10%) And Tetramethylethylenediamine (Tmeda) (10%). This Catalytic Protocol Showed Good Functional Group Tolerance As Well As Excellent Regioselectivity For Unsymmetrical Imides Bearing
合成参考文献
摘要:Sako, M., Science of Synthesis, (2004) 16, 1222.