CAS: 4664-00-0; 2,3-Pyridinedicarboximide

该化合物是一种杂交有机化合物,其特点是有引信的quinoline 和 imide 结构,具有多功能反应性和稳定性. 它的僵硬芳香框架和缺电子性使其在合成化学中具有价值,特别是作为制药,农用化学和先进材料的构件. 该化合物参与循环添加,核生殖替代和金属催化混合反应的能力增强了其在构建复杂的分子结构中的效用. 此外, Quinolimide 衍生物由于其可金枪鱼电子特性,在光电子学中具有潜在应用潜力. 它的热性和氧化性稳定性进一步支持其在高性能材料中的使用. 研究者们赞成基诺尼米德的平衡反应性和功能性.

结构式图片

相似化合物

18184-75-3 23439-87-4 115012-09-4

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合成工艺路线路线简述

  • 合成目标产物 5H-Pyrrolo[3,4-B]Pyridine-5,7(6H)-Dione 主要起始原料 Quinolinic Acid
  • (文献来源)合成步骤主要原料 Quinolinic Acid
Alkaline Earth Salt Of/the/ Methylsulfuric Acid 反应生成 2,3-吡啶二酰亚胺
参考文献:Philips,Justus Liebigs Annalen Der Chemie,1895,Vol. 288,P. 257
标题:Philips,Justus Liebigs Annalen Der Chemie,1895,Vol. 288,P. 257

海关参考信息

专利信息


专利号:US-8471006-B2
优先权日:2003-10-31
标题:Coupling agents for peptide synthesis
发明人:CARPINO LOUIS A; XIA JUSONG; ZHANG CHONGWU; SFERDEAN CALIN DAN
权利人:CARPINO LOUIS A; XIA JUSONG; ZHANG CHONGWU; SFERDEAN CALIN DAN; UNIV MASSACHUSETTS
摘要:The present invention is directed to compounds of the formula: n nor salts thereof or N-oxides and their use in peptide synthesis.

专利号:US-7468375-B2
优先权日:2004-04-26
标题:Inhibitors of the HIV integrase enzyme
发明人:DRESS KLAUS RUPRECHT; HU QIYUE; JOHNSON TED WILLIAM; PLEWE MICHAEL BRUNO; TANIS STEVEN PAUL; WANG HAI; YANG ANLE; YIN CHUNFENG; ZHANG JUNHU
权利人:PFIZER
摘要:The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIVâ€?) integrase enzyme.

专利号:CN-111100068-A
优先权日:2019-12-29
标 题 :A kind of method for fast and efficient synthesis of methyl 3-aminoisonicotinate

专利号:US-7122549-B2
优先权日:2000-11-03
标题:Saframycins, analogues and uses thereof
发明人:MYERS ANDREW G; PLOWRIGHT ALLEYN T
权利人:HARVARD COLLEGE
摘要:In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel compounds of general formula (I), and methods for the synthesis thereof. n n n n n n n n n n In another aspect, the present invention provides pharmaceutical compositions comprising a compound of formula (I) and a pharmaceutically acceptable carrier. In yet another aspect, the present invention provides methods for treating cancer comprising administering a therapeutically effective amount of a compound of formula (I) to a subject in need thereof.

专利号:US-8361516-B2
优先权日:2006-08-03
标 题:Composition comprising sarsasapogenin
发明人:LINTNER KARL; MAS CHAMBERLIN CLAIRE
权利人:SEDERMA SA; LINTNER KARL; MAS CHAMBERLIN CLAIRE
摘要:The présent invention relates to a composition comprising sarsasapogenin or a plant extract containing it in order to improve the gêneral state of the skin and in particular to improve and/or embellish any part of the body showing a déficit in lipids. More particularly, the invention is directed to a cosmetic method to improve the figure, comprising the step of topically applying to the skin a cosmetic or dermopharmaceutical composition comprising sarsasapogenin to favour the expansion and/or the formation of the subcutaneous adipose tissue, and/or to favour the lipid synthesis in the epidermis.

专利号:CN-115010709-A
优先权日:2022-07-06
标 题:Synthesis method of pyrrolo [3,4-b ] pyridine-5, 7-dione
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主要参考文献

参考标题:Zinc-Catalyzed Selective Reduction Of Cyclic Imides With Hydrosilanes: Synthesis Of ω-Hydroxylactams
作者:Guangni Ding,Bin Lu,Yuyuan Li,Jun Wan,Zhaoguo Zhang,Xiaomin Xie |发布日期:2015.3.23
摘要:Cyclic Imides Were Selectively Reduced To The Corresponding ω‐hydroxylactams In High Yields With (Eto)3Sih (Triethoxysilane) Or Pmhs (Polymethylhydrosiloxane) Under Catalysis Of Zinc Diacetate Dehydrate [zn(Oac)2⋅2 H2O] (10%) And Tetramethylethylenediamine (Tmeda) (10%). This Catalytic Protocol Showed Good Functional Group Tolerance As Well As Excellent Regioselectivity For Unsymmetrical Imides Bearing

合成参考文献


摘要:Sako, M., Science of Synthesis, (2004) 16, 1222.
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