CAS: 914225-70-0; 1-(5-Fluoro-2-Iodophenyl)Ethanone

• 英文名称1-(5-Fluoro-2-Iodophenyl)Ethanone
• 中文名称1-(5-氟-2-碘苯基)乙酮
• IUPAC名称1-(5-fluoro-2-iodophenyl)ethan-1-one
• 其它别名2'-碘-5'-氟苯乙酮; 5'-Fluoro-2'-Iodoacetophenone
• CAS编号914225-70-0
• MFCD编号:MFCD09033159
• EINECS号:812-223-8
• 分子式:C8H6FIO
• 分子量:264.04
• 产品CID: 1950150
• 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

• 相似结构搜索
• InChIKey: NRLSRIONJVBZDT-UHFFFAOYSA-N
• InChI=1S/C8H6FIO/c1-5(11)7-4-6(9)2-3-8(7)10/h2-4H,1H3…
• 计算化学: 氢键受体数1.0氢键供体数0.0可旋转键数1.0

物理性质

• 沸点269.5°C at 760 mmHg
• 闪点116.8±23.2°C
• 密度1.8±0.1 g/cm3
• PSA:17.07
• LogP:2.6329
• 折射率1.583
• 蒸汽压0.0±0.6 mmHg at 25°C
• 溶解性Slightly Soluble In Water.
• 敏感性光敏感
• 外观形态棕色液体
• 储存条件置于阴暗处,密封, 常温干燥保存
• 产品应用该化合物用于药物中间体.

MSDS等安全信息

• GHS象形图
• GHS符号GHS07;
  注释: Exclamation mark
• 危险类别特定目标器官毒性 - 单次接触 类别3
  皮肤腐蚀/刺激 类别2
  严重眼刺激 类别2
• 警示词Warning(警告)
• 危险描述H335 |可能引起呼吸道刺激.
  H315 |造成皮肤刺激.
  H319 |造成严重眼刺激.
• 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
• 危险品标志Xi

欧盟法规

上下游产品

合成工艺路线路线简述

• 2343-25-1 = 914225-70-0
  反应条件:1.1 Reagents: Acetic Acid,Sulfuric Acid,Potassium Nitrite Solvents: Water; 0 °C; 30 Min,0 °C; 1 H,0 °C -> Rt; Rt -> 0 °C1.2 Reagents: Potassium Iodide Solvents: Water; 30 Min,0 °C; 1 H,0 °C -> Rt
  标题:Copper-Catalyzed Ligand-Free Amidation Of Aryl Iodides And Amino Acid Amides To Synthesize C3-(Z)-1H-Benzo[e][1,4]Diazepin-2(3H)-Ones
  作者:Hu,Xiao; Et Al
  参考文献:Molecular Diversity 日期:2015 卷标:19(4) 页码:695-701]
  
  108-59-8 + 52548-63-7 = 914225-70-0
  反应条件:1.1 Reagents: Oxalyl Chloride Catalysts: Dimethylformamide Solvents: Dichloromethane; Rt -> 0 °C; 0 °C; 2 H,Rt1.2 Reagents: Triethylamine,Magnesium Chloride Solvents: Acetonitrile; 45 Min,0 °C1.3 Solvents: Acetonitrile; 0 °C -> Rt; 3 H,Rt1.4 Reagents: Lithium Chloride Solvents: Dimethylformamide,Water; 4 H,100 °C
  标题:Palladium-Catalyzed Alkylation With Alkyl Halides By C(Sp3)-H Activation
  作者:Wu,Zhuo; Et Al
  参考文献:Angewandte Chemie 日期:2017 卷标:56(40) 页码:12288-12291]
  
  108-59-8 + 1261781-96-7 = 914225-70-0
  反应条件:1.1 Reagents: Triethylamine,Magnesium Chloride Solvents: Acetonitrile; 45 Min,0 °C1.2 Solvents: Acetonitrile; 0 °C -> Rt; 3 H,Rt1.3 Reagents: Lithium Chloride Solvents: Dimethylformamide,Water; 4 H,100 °C
  标题:Palladium-Catalyzed Alkylation With Alkyl Halides By C(Sp3)-H Activation
  作者:Wu,Zhuo; Et Al
  参考文献:Angewandte Chemie 日期:2017 卷标:56(40) 页码:12288-12291]
  
  52548-63-7 = 914225-70-0 [标题:Reaction Conditions
  标题:Palladium-Catalyzed Sequential C-H Activation/amination With Diaziridinone: An Approach To Indoles
  作者:Li,Jing; Et Al
  参考文献:Organic Letters 日期:2021 卷标:23(9) 页码:3646-3651]
  
  52548-63-7 = 914225-70-0
  反应条件:1.1 Reagents: Oxalyl Chloride Catalysts: Dimethylformamide Solvents: Dichloromethane; 0 °C; 2 H,Rt2.1 Reagents: Triethylamine,Magnesium Chloride Solvents: Acetonitrile; 45 Min,0 °C2.2 Solvents: Acetonitrile; 0 °C -> Rt; 3 H,Rt2.3 Reagents: Lithium Chloride Solvents: Dimethylformamide,Water; 4 H,100 °C
  标题:Palladium-Catalyzed Alkylation With Alkyl Halides By C(Sp3)-H Activation
  作者:Wu,Zhuo; Et Al
  参考文献:Angewandte Chemie 日期:2017 卷标:56(40) 页码:12288-12291]
  
  61272-77-3 = 914225-70-0
  反应条件:1.1 Solvents: Diethyl Ether; Rt; Reflux; Reflux -> Rt1.2 Reagents: Hydrochloric Acid Solvents: Water; 30 Min,Rt -> Reflux; Cooled1.3 Reagents: Sodium Bicarbonate Solvents: Water2.1 Reagents: Acetic Acid,Sulfuric Acid,Potassium Nitrite Solvents: Water; 0 °C; 30 Min,0 °C; 1 H,0 °C -> Rt; Rt -> 0 °C2.2 Reagents: Potassium Iodide Solvents: Water; 30 Min,0 °C; 1 H,0 °C -> Rt
  标题:Copper-Catalyzed Ligand-Free Amidation Of Aryl Iodides And Amino Acid Amides To Synthesize C3-(Z)-1H-Benzo[e][1,4]Diazepin-2(3H)-Ones
  作者:Hu,Xiao; Et Al
  参考文献:Molecular Diversity 日期:2015 卷标:19(4) 页码:695-701

海关参考信息

• 2902600000-乙苯
  2912110000-甲醛
  2912120000-乙醛
  2912210000-苯甲醛
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

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