CAS: 108-47-4; 2,4-Lutidine

上下游产品

CAS号75-05-8 乙腈 | CAS号78-79-5 异戊二烯 | CAS号41438-38-4 2,4-二乙基吡啶二羧酸 | CAS号1074-99-3 2,4-二甲基-5-硝基吡啶 | CAS号1074-76-6 2,4-二甲基-3-硝基吡啶 | CAS号50-00-0 甲醛 | CAS号67-64-1 丙酮 | CAS号74-86-2 乙炔 | CAS号690-94-8 DIMETHYL(VINYL)... | CAS号108-44-1 3-甲基苯胺 | CAS号1122-45-8 2,4-二甲基吡啶 N-氧化物 | CAS号38198-16-2 2-氯-4-甲基吡啶 | CAS号68265-89-4 4-methyl-2-(tri... | CAS号357263-42-4 7-甲基-5-氮杂吲哚 | CAS号598-94-7 N,N-二甲基脲 | CAS号493-77-6 2,4,6-三苯基三嗪 | CAS号106932-30-3 methyl-4 phenyl... | CAS号143509-46-0 6-(1,3-dioxolan... | CAS号499-80-9 吡啶-2,4-二羧酸

2,4-二甲基吡啶 1-氧化物置于bis(Triphenyl)Oxodiphosphonium Trifluoromethanesulfonate Salt,Potassium Iodide体系中,用 乙醇 用作溶剂,化学反应 1.17H,以93%的收率获得2,4-二甲基吡啶
参考文献:N-杂芳族化合物的h 2 O 2温和有效的氧合反应,生成胺n-氧化物,Ki与三氟甲磺酸六苯基氧二phosph合,再氧化成叔胺
标题:N-杂芳族化合物的h 2 O 2温和有效的氧合反应,生成胺n-氧化物,Ki与三氟甲磺酸六苯基氧二phosph合,再氧化成叔胺
摘要:报道了在室温下在etoh中三氟甲磺酸六苯基氧二磷鎓(hendrickson试剂)存在下使用h 2 O 2将n-杂芳族化合物氧化为相应的n-氧化物的温和有效的方法.该方法论提出了相对快速和选择性的反应,以非常好的收率提供了n-氧化物.还通过ki在相同反应条件下进行逆反应,脱氧反应,以产生叔胺.
Doi:10.1007/s13738-018-1381-4

专利信息

专利号:US-10011567-B1
优先权日:2017-03-09
标题 :Method for the synthesis of acrylate derivatives
发明人：WANG MINGWEN; ZHANG YUE
权利人:INNOSCI LLC
摘要:The present invention provides an improved synthesis of a salt of acrylate derivatives. The synthesis generally includes the preparation of an ester or an amide containing a leaving group followed by the formation of a salt.

专利号:US-4801744-A
优先权日:1985-03-01
标 题 :Catalytic synthesis of urea from carbon monoxide and amine compound
发明人：HERMAN JEAN-JACQUES; LECLOUX ANDRE
权利人:SOLVAY
摘要:Process for the catalytic synthesis of nitrogen-containing organic compounds, comprising the reaction of carbon monoxide with at least one amino compound in a reaction mixture containing a catalyst based on selenium and a substituted pyridine. The process is particularly suitable for the synthesis of ureas and of their polymers.

专利号:US-10913749-B2
优先权日:2015-05-07
标 题 :Macrocyclization reactions and intermediates and other fragments useful in the synthesis of halichondrin macrolides
发明人：FANG FRANCIS G; KIM DAE-SHIK; CHOI HYEONG-WOOK; CHASE CHARLES E
权利人:EISAI R&D MAN CO LTD
摘要:The invention provides methods for the synthesis of a halichondrin macrolides through a macrocyclization strategy. The macrocyclization strategy of the present invention involves subjecting a non-macrocyclic intermediate to a carbon-carbon bond-forming reaction (e.g., an olefination reaction (e.g., Horner-Wadsworth-Emmons olefination), catalytic Ring-Closing Olefin Metathesis, or Nozaki-Hiyama-Kishi reaction) to afford a macrocyclic macrolide. The invention also provides compounds useful as intermediates in the synthesis of a halichondrin macrolides and methods for preparing the same.

专利号:US-2025179020-A1
优先权日:2023-12-05
标 题:Synthesis of bis-oxime heterocycles
发明人：BLUMBERG SHAWN T; DORSEY CHRISTOPHER L
权利人:SOUTHWEST RES INST
摘要:A synthesis of bis-oxime heterocycles via reaction of 2,4-dimethyl pyridine or 2,4-dimethylpyrimidine in the presence of a phase transfer catalyst. Such bis-oxime heterocycles provide a more direct route to the synthesis of bis-quaternary pyridinium compounds and their analogs as nerve agent antidotes.

专利号:US-2023287032-A1
优先权日:2020-08-14
标 题:Synthesis of fluorinated nucleotides
发明人：CHUNG CHEOL KEUN; LIU ZHIJIAN; MALIGRES PETER E; MAO EDNA; OBLIGACION JENNIFER V; PHILLIPS ERIC M; PIRNOT MICHAEL; POIRIER MARC; SONG ZHIGUO JAKE; WANG TAO
权利人:CHUNG CHEOL KEUN; LIU ZHIJIAN; MALIGRES PETER E; MAO EDNA; OBLIGACION JENNIFER V; PHILLIPS ERIC M; PIRNOT MICHAEL; POIRIER MARC; SONG ZHIGUO JAKE; WANG TAO; MERCK SHARP & DOHME LLC
摘要:The present invention relates to efficient processes useful in the preparation of fluorinated nucleosides, such as (O—{[(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methyl}O,O-dihydrogen phosphorothioate, also known as 2′-(S)-fluoro-thio-adenosine monophosphate or 2′-F-thio-AMP. Such fluorinated nucleosides may be useful as a biologically active compound and or as an intermediate for the synthesis of more complex biologically active compounds. The present invention also encompasses intermediates useful in the disclosed synthetic processes and the methods of their preparation.

专利号:US-2023174567-A1
优先权日:2020-05-22
标题:Synthesis of fluorinated nucleotides
发明人：ARMIGER TRAVIS; BELYK KEVIN M; BENKOVICS TAMAS; CHUNG CHEOL K; JI CHEN YINING; JOHNSON HEATHER CLAIRE; KLAPARS ARTIS; LIU ZHIJIAN; LIU ZHUQING; MOORE JEFFREY C; NEEL ANDREW J; PENG FENG; RUMMELT STEPHAN M; SALEHI MARZUARANI NASTARAN; SHERRY BENJAMIN D; SONG ZHIGUO JAKE; TURNBULL BEN WILLIAM HULME; WANG LU; XU FENG
权利人:MERCK SHARP & DOHME LLC
摘要:The present invention relates to efficient processes useful in the preparation of fluorinated nucleosides, such as (2S,3R,4S,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-fluoro-4-hydroxy-2-(mercaptomethyl)tetrahydrofuran-3-yl dihydrogen phosphate, also known as 3′-fluoro-thio-guanosine monophosphate or 3′-F-thio-GMP. Such fluorinated nucleosides may be useful as a biologically active compound and or as an intermediate for the synthesis of more complex biologically active compounds. The present invention also encompasses intermediates useful in the disclosed synthetic processes and the methods of their preparation. (I)