CAS: 138343-75-6; 2-(N-Boc-Amino)-3-Methylpyridine

相似化合物

1603-40-3 156267-13-9 1228631-58-0

上下游产品

CAS号1603-40-3 2-氨基-3-甲基吡啶 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号1014613-50-3 2-环丙基-1H-吡咯并[2,... | CAS号10299-69-1 2,3-二甲基-7-氮杂吲哚 | CAS号138343-77-8 1H-吡咯并[2,3-b]吡啶... | CAS号145901-11-7 1H-吡咯[2,3-B]吡啶-6-胺 | CAS号149489-03-2 N-(3-乙基-2-吡啶基)氨... | CAS号23612-48-8 2-甲基-7-氮杂吲哚 | CAS号221675-35-0 1H-吡咯并[2,3-b]吡啶...

2-氨基-3-甲基吡啶,二碳酸二叔丁酯 以 叔丁醇 用作溶剂,化学反应 24.0H,反应生成2-(Boc-氨基)-3-甲基吡啶
参考文献:通过c-c和c-n键断裂的n-苄基-2-氨基吡啶的无金属串联脱甲基/ C(sp 2)-h环氨基化过程
标题:通过c-c和c-n键断裂的n-苄基-2-氨基吡啶的无金属串联脱甲基/ C(sp 2)-h环氨基化过程
摘要:已经开发了一种轻度,无金属的合成方法,该方法以n-苄基-2-氨基吡啶为原料,以phi(opiv)2为化学计量氧化剂,合成了吡啶并[1,2-A ]苯并咪唑类化合物.该过程由一个不寻常的岛(opiv)发起2介导的本位小号ë的ar反应,接着进行溶剂辅助c-C和c-N键断裂.
Doi:10.1021/ol4015656

专利信息

专利号:US-5681959-A
优先权日:1995-02-21
标题:Chemical synthesis of azaindoles
发明人：BISHOP BRIAN CCHRISTOPHER; COTTRELL IAN FRANK; CAMERON MARK; HANDS DAVID
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to a process for the preparation of azaindole derivatives of the formula ##STR1## wherein Q is hydrogen, C 1-6 alkyl, C 2-6 alkenyl, C 1-6 alkoxy, hydroxy, aryl or arylC 1-4 alkyl; n one of X, Y and Z is --Nâ•? and the others are --CHâ•?; n R 1 is hydrogen, C 1-6 alkyl, C 2-6 alkenyl or C 1-6 alkyl substituted by a group selected from aryl or --NR 2 R 3 where R 2 and R 3 each independently represent C 1-4 alkyl, or R 2 and R 3 , together with the nitrogen atom to which they are attached, form a 4-7 membered saturated heterocyclic ring, optionally containing in the ring an oxygen or sulphur atom or a group NR 4 where R 4 is C 1-4 alkyl, aryl or arylC 1-4 alkyl; and n R 5 is a hydrogen atom or a group selected from C 1-6 alkyl or aryl.

专利号:GB-2298199-A
优先权日:1995-02-21
标题:Synthesis of azaindoles