CAS: 152126-31-3; 3-Fluoropicolinic Acid

相似化合物

31224-43-8 97509-75-6 31181-79-0

上下游产品

CAS号860296-21-5 4-氯-3-氟吡啶-2-甲酸 | CAS号372-47-4 3-氟吡啶 | CAS号124-38-9 二氧化碳 | CAS号2546-56-7 4-氯-3-氟吡啶 | CAS号869108-35-0 3-氟吡啶-2-羧酸甲酯

3-氟吡啶置于palladium On Activated Charcoal 2,2,6,6-四甲基哌啶,正丁基锂,氢气,Ammonium Formate,Lithium Diisopropyl Amide体系中,用 四氢呋喃,乙醇,正己烷 用作溶剂,化学反应 8.17H,反应生成3-氟吡啶-2-羧酸
参考文献:将核心化合物转化为积木:区域化学穷举功能化的概念
标题:将核心化合物转化为积木:区域化学穷举功能化的概念
摘要:在模型研究中,3-氟苯酚和 3-氟吡啶通过相应的有机金属中间体转化为相应羧酸的所有可能的区域异构体.正如对调查结果进行概括的尝试所揭示的那样,一套有限的原则和方法足以应对所有性病.场景.用于区域化学的最有价值和通用的工具.多种底物模式的详尽功能化是可选的位点选择性金属化(通过试剂/底物匹配或外围配位控制),使用激活或拥塞保护基团和碱性梯度驱动的重卤素迁移(随后是卤素/金属排列).[在 Scifinder (R) 上]
Doi:10.1002/ejoc.200400895

专利信息

专利号:US-10906888-B2
优先权日:2016-07-14
标 题:Pyrimidine carboxamides as inhibitors of Vanin-1 enzyme
发明人：CASIMIRO-GARCIA AGUSTIN; STROHBACH JOSEPH WALTER; HEPWORTH DAVID; LOVERING FRANK ELDRIDGE; CHOI CHULHO; ALLAIS CHRISTOPHE PHILIPPE; WRIGHT STEPHEN WAYNE
权利人:PFIZER
摘要:Compounds, pharmaceutically acceptable salts thereof, are disclosed wherein the compounds have the structure of (I) as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

专利号:US-10308615-B2
优先权日:2015-05-29
标 题:Heterocyclic compounds as inhibitors of Vanin-1 enzyme
发明人：CASIMIRO-GARCIA AGUSTIN; CONDON JEFFREY SCOTT; FLICK ANDREW CHRISTOPHER; GOPALSAMY ARIAMALA; KIRINCICH STEVEN J; MATHIAS JOHN PAUL; STROBACH JOSEPH WALTER; XIANG JASON SHAOYUN; XING LI HUANG; WANG XIAOLUN
权利人:PFIZER
摘要:Compounds, pharmaceutically acceptable salts thereof, are disclosed wherein the compounds have the structure of n nas defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

专利号:WO-2011026581-A1
优先权日:2009-09-03
标题:Continuous synthesis of carbon-coated lithium-iron-phosphate

专利号:FR-2686340-A1
优先权日:1992-01-22
标题:PROCESS FOR THE SYNTHESIS OF CARBOXYLIC PYRIDINES OR ORTHOHALOGENATED CARBOXAMIDES AND NOVEL CARBOXYLIC PYRIDINES OR ORTHOFLUOROUS CARBOXAMIDES.

专利号:EP-2292557-A1
优先权日:2009-09-03
标题 :Continuous synthesis of carbon-coated lithium-iron-phosphate

专利号:EP-2475615-A1
优先权日:2009-09-03
标题:Continuous synthesis of carbon-coated lithium-iron-phosphate