CAS: 342-24-5; 2-Fluorobenzophenone

上下游产品

1,2-bis-(2-fluoro-phenyl)-1,2-diphenyl-ethane-1,2-diol Phenetole 2-Fluorobenzoyl chloride (2-Fluoro-4-trimethylsilanyl-phenyl)-phenyl-methanone 1-fluoro-2-(1-phenylethenyl)benzene 1-(2-fluorophenyl)-1-phenylethan-1-ol 1,2-bis-(2-fluoro-phenyl)-1,2-diphenyl-ethane-1,2-diol 2-fluorobenzhydrol

N-甲基苯甲酰胺置于cinnamyl,Sodium Hydride,Potassium Carbonate体系中,用 四氢呋喃,水 作为反应溶剂,化学反应 63.17H,反应生成 邻氟二苯甲酮
参考文献:N-甲基氨基嘧啶酰胺(mapa):催化n-c(o)裂解的高反应性电子活化酰胺
标题:N-甲基氨基嘧啶酰胺(mapa):催化n-c(o)裂解的高反应性电子活化酰胺
摘要:尽管最近在催化交叉偶联技术方面取得了进展,但n-烷基-N-芳基酰胺的直接活化一直是具有挑战性的转化.在这里,我们报告的第一suzuki交叉偶联的ñ甲基氨基嘧啶基酰胺(mapa)由受控启用ñ ñ->π氩缀合,将所得的酰胺键的部分双键特征的重塑.酰胺活化的新模式适用于从未活化的伯酰胺和仲酰胺反应生成酰基金属中间体.
DOI:10.1021/acs.Orglett.7B02288

专利信息

专利号:US-8981036-B2
优先权日:2012-08-02
标 题:Synthesis of and curing additives for phthalonitriles
发明人：KELLER TEDDY M; LASKOSKI MATTHEW
权利人:KELLER TEDDY M; LASKOSKI MATTHEW; US NAVY
摘要:A composition having a mixture of the below compounds having a mole ratio of at least 1:20. Ar 1 and Ar 2 are independently selected aromatic groups. A composition comprising phthalonitrile compounds that comprise at least 5 mol % of the first compound below. n nA method of: providing a solution of a dichloroaromatic compound having an electron-withdrawing group bound to each aromatic ring containing one of the chloride groups; a dihydroxyaromatic compound or anion thereof; an organic transition metal complex or a transition metal salt; an alkaline hydroxide base; and a solvent; and heating the solution to a temperature at which the dichloroaromatic compound and the dihydroxyaromatic compound react to form a dimetallic salt of an aromatic ether oligomer. The molar ratio of the dihydroxyaromatic compound to the dichloroaromatic compound is greater than 2:1. Water formed during the heating is concurrently distilled from the solution.

专利号:WO-2015183518-A1
优先权日:2013-03-15
标 题:Synthesis of and curing additives for phthalonitriles
发明人：KELLER TEDDY M; LASKOSKI MATTHEW; SAAB ANDREW
权利人:US GOVERNMENT; KELLER TEDDY M; LASKOSKI MATTHEW; SAAB ANDREW
摘要:A method of: providing a solution of a dichloroaromatic compound having an electron- withdrawing group bound to each aromatic ring containing one of the chloride groups; a dihydroxyaromatic compound or anion thereof; an organic transition metal complex or a transition metal salt; a base; and a solvent; and heating the solution to a temperature at which the dichloroaromatic compound and the dihydroxyaromatic compound react to form a dimetallic salt of an aromatic ether oligomer. The molar ratio of the dihydroxyaromatic compound to the dichloroaromatic compound is greater than 2: 1. Water formed during the heating is concurrently distilled from the solution. A composition having a mixture of the below compounds having a mole ratio of at least 1:20. Ar 1 and Ar 2 are independently selected aromatic groups. A composition comprising phthalonitrile compounds that comprise at least 5 mol% of the first compound below.

专利号:US-8735532-B2
优先权日:2012-08-02
标题 :Synthesis of and curing additives for phthalonitriles
发明人：KELLER TEDDY M; LASKOSKI MATTHEW; SAAB ANDREW
权利人:KELLER TEDDY M; LASKOSKI MATTHEW; SAAB ANDREW; US NAVY
摘要:A method of: providing a solution of a dichloroaromatic compound having an electron-withdrawing group bound to each aromatic ring containing one of the chloride groups; an excess of a dihydroxyaromatic compound; an organic transition metal complex or a transition metal salt; a base; and a solvent; and heating the solution to a temperature at which the dichloroaromatic compound and the dihydroxyaromatic compound react to form an aromatic ether oligomer that is a dihydroxy-terminated compound or a dimetallic salt thereof. Water formed during the heating is concurrently distilled from the solution. A method of curing a phthalonitrile monomer in the presence of an acid and a curing agent to form a phthalonitrile thermoset.

专利号:US-8859712-B2
优先权日:2012-08-02
标 题 :Synthesis of and curing additives for phthalonitriles
发明人：KELLER TEDDY M; LASKOSKI MATTHEW; SAAB ANDREW
权利人:KELLER TEDDY M; LASKOSKI MATTHEW; SAAB ANDREW; US GOVERNMENT
摘要:A method of: providing a solution of a dichloroaromatic compound having an electron-withdrawing group bound to each aromatic ring containing one of the chloride groups; a dihydroxyaromatic compound; an organic transition metal complex or a transition metal salt; a base; and a solvent; and heating the solution to a temperature at which the dichloroaromatic compound and the dihydroxyaromatic compound react to form a dimetallic salt of an aromatic ether oligomer. The molar ratio of the dihydroxyaromatic compound to the dichloroaromatic compound is greater than 2:1. Water formed during the heating is concurrently distilled from the solution.

专利号:WO-9966934-A1
优先权日:1998-06-22
标 题 :CYCLIC AMINO ACID COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS
发明人：AUDIA JAMES E; DRESSMAN BRUCE A; SHI QING
权利人:ELAN PHARM INC; LILLY CO ELI; AUDIA JAMES E; DRESSMAN BRUCE A; SHI QING
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-2014039151-A1
优先权日:2012-08-02
标 题:Synthesis of and curing additives for phthalonitriles