CAS: 4964-71-0; 5-Bromoquinoline

相似化合物

3964-04-3 700871-88-1 34522-69-5

上下游产品

CAS号611-34-7 5-氨基喹啉 | CAS号91-22-5 喹啉 | CAS号333383-82-7 N-(3-bromopheny... | CAS号333383-83-8 N-(3-bromopheny... | CAS号591-19-5 3-溴苯胺 | CAS号7510-48-7 N-(3-溴苯基)-4-甲基苯磺酰胺 | CAS号83922-51-4 N-(3-溴苯基)甲烷磺酰胺 | CAS号56-81-5 甘油 | CAS号580-15-4 6-氨基喹啉 | CAS号50358-42-4 5-溴喹啉-6-胺 | CAS号394-69-4 5-氟喹啉 | CAS号355386-94-6 喹啉-5-硼酸 | CAS号152150-03-3 2-quinolin-5-yl... | CAS号99455-13-7 5-溴-2-氯喹啉 | CAS号1404431-48-6 7-bromo-1a,2,3,... | CAS号3056-03-9 1H-quinoline-5-... | CAS号176967-80-9 5-溴-8-硝基喹啉 | CAS号855837-58-0 5-bromo-6-nitro... | CAS号67532-97-2 5-(TriMethylsil... | CAS号804430-48-6 8-Quinolinesulf...

喹啉置于三氟甲磺酸,1,3-二溴-1,3,5-三嗪-2,4,6-三酮体系中,化学反应 1.67H,反应生成 5-溴喹啉
参考文献:Bromination Of Isoquinoline,Quinoline,Quinazoline And Quinoxaline In Strong Acid
标题:Bromination Of Isoquinoline,Quinoline,Quinazoline And Quinoxaline In Strong Acid
摘要:苯并吡嗪和苯并二嗪的溴化反应通常得到多种产物混合物.本文中,我们展示了异喹啉(1)可在浓硫酸中使用nbs或在三氟甲磺酸中使用n,N'-二溴异氰尿酸(dbi)进行区域选择性单溴化,得到5-溴异喹啉(2).研究发现,溴化反应对溴化剂,酸,温度和浓度的选择非常敏感.喹啉,喹唑啉和喹喔啉亦可进行类似溴化,尽管其区域选择性不如异喹啉强烈.
DOI:10.1055/s-2002-19314

专利信息

专利号:US-8633182-B2
优先权日:2012-05-30
标题:Indanyloxyphenylcyclopropanecarboxylic acids
发明人：HAMPRECHT DIETER; FRATTINI SARA; LINGARD IAIN; PETERS STEFAN
权利人:HAMPRECHT DIETER; FRATTINI SARA; LINGARD IAIN; PETERS STEFAN; BOEHRINGER INGELHEIM INT
摘要:The present invention relates to compounds of general formula I, n nwherein the groups R 1 , R 2 , R 3 , m and n are defined as in claim 1 , which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.

专利号:CN-115433125-A
优先权日:2022-09-15
标题 :A new method for the synthesis of 2-tert-butoxyquinoline derivatives

专利号:CN-106588926-A
优先权日:2016-12-28
标 题 :A kind of 2,7-diaza[3,2,1]bicyclooctane and its derivatives and their synthesis method and application

专利号:CN-106588926-B
优先权日:2016-12-28
标题:A kind of 2,7-diaza[3,2,1]bicyclooctane and its derivatives and their synthesis method and application

专利号:CN-113214149-B
优先权日:2021-03-03
标题 :Synthesis method of phenyl (quinoline-8-yl) ketone derivative