CAS: 5053-06-5; Fenspiride

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CAS号32315-10-9 三光气 | CAS号23808-42-6 4-(氨基甲基)-1-(2-苯... | CAS号39742-60-4 1-苯乙基-4-哌啶酮 | CAS号105-58-8 碳酸二乙酯

N-(2-苯乙基)-4-哌啶酮置于lithium Aluminium Tetrahydride,Zinc(II) Iodide体系中,用 乙醚,二氯甲烷 作为反应溶剂,化学反应 10.0H,反应生成 芬司匹利
参考文献:Convenient Synthesis Of 1-Oxa-3,8-Diazaspiro [4,5] Decan-2-Ones
标题:Convenient Synthesis Of 1-Oxa-3,8-Diazaspiro [4,5] Decan-2-Ones
摘要:Synthesis Of 1-Oxa-3,8-Diazospiro [4,5] Decan-2-Ones From 4-Pyridone By Addition Of Trimethylsilyl Cyanide.
DOI:10.1080/00397919408011753

专利信息

专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

专利号:EP-0934113-B1
优先权日:1996-10-22
标题:Inverse filtration apparatus and method of use
发明人：ZUCKERMANN RONALD N; CHINN JASON P; DESAI MANOJ C; JONES DAVID C
权利人:CHIRON CORP
摘要:An inverse filtration head (2, 202, 60, 104) and an apparatus including the filtration head are provided for use in solid phase chemical synthesis methods, such as in the synthesis of polypeptides, peptoids, polynucleotides and other molecules synthesized by solid phase techniques. The inverse filtration head (2, 202, 60, 104) includes a plurality of influent/effluent conduit pairs (4, 204) arranged in a substantially parallel array. The conduit pairs (4, 204) are used to simultaneously aspirate and/or wash and fill a plurality of reaction vessels arranged in a corresponding order array. An inverse filtration device (52) is also provided. The filtration device (52) includes an inverse filtration head (2, 202, 60, 104) and a control panel (106) which allows actuation of associated gas, fluids and vacuum delivery means for delivery to and from the filtration head (2, 202, 60, 104). An inverse filtration apparatus (102) is provided which includes the inverse filtration device (52), a valve box (108) and associated fluid (130, 134), gas and vacuum sources (132).

专利号:US-RE41998-E
优先权日:1990-02-26
标题 :Compositions and methods of treatment of sympathetically maintained pain
发明人：CAMPBELL JAMES N
权利人:ARCLON THERAPEUTICS INC
摘要:Sympathetically maintained pain is treated topically by administering to the site where sympathetically maintained pain is present an α-1-adrenergic antagonist, α-2-adrenergic agonist, or other drug that depletes or blocks synthesis of sympathetic norepinephrine, known collectively as sympatholytic agents. Chemical formulas for several sympatholytic agents are given.

专利号:WO-0155129-A1
优先权日:2000-01-27
标题:Synthesis of macrocyclic monomers
发明人：LEITNER WALTER; JANSSEN EDO; FUERSTNER ALOIS; PICKENHAGEN WILHELM; PANTEN JOHANNES
权利人:STUDIENGESELLSCHAFT KOHLE MBH; DRAGOCO GERBERDING CO AG; LEITNER WALTER; JANSSEN EDO; FUERSTNER ALOIS; PICKENHAGEN WILHELM; PANTEN JOHANNES
摘要:A method for the production of a macrocyclic monomer ( for example, ethylene brassylate) comprises the following steps: treatment of a polymer (for example, polyethylene brassylate) with a supercritical fluid, under conditions which bring about a depolymerisation of the polymer to macrocyclic monomers, extraction of the macrocyclic monomer, with the supercritical fluid as extraction agent and separation of the supercritical fluid from the macrocyclic monomer. The extraction can be carried out continuously and/or simultaneous to the treatment of the polymer with the supercritical fluid.

专利号:EP-1175668-B1
优先权日:1999-04-19
标 题 :Device for calculating and generating signals, especially for digital sound synthesis
发明人：RABENSTEIN RUDOLF DR-ING HABIL; TRAUTMANN LUTZ DIPL-ING
权利人:FTMUSICS GMBH
摘要:The invention relates to a system for generating signals, especially for the digital sound synthesis, and comprises a computer (35) for calculating coefficients in dependence on the signal to be generated, a coefficient memory (36) for storing the calculated coefficients and an arrangement (38) of a plurality of digital devices (5 to 7) that is linked with the coefficient memory (36). The signal to be generated is output at the output (40) of said digital devices. The system further comprises an excitation device (37) that is linked with the arrangement (38) and that feeds excitation signals to the arrangement (38), a control device (39) for controlling the coefficient memory (36), the excitation device (37) and the arrangement (38) in such a manner that the arrangement (38) is operated with the calculated and stored coefficients and the excitation signals.

专利号:WO-8102985-A1
优先权日:1980-04-14
标 题:Method for the separation of mixture by means of exchange of materials at different temperatures or pressures
发明人：SILBERRING L
权利人:SILBERRING L
摘要:In the method for the separation of mixtures by means of exchange of different phases which, at least partially, circulate in counter current in a closed circuit, a portion (1, 2) of exchange equipment, works at high temperatures or at a high pressure and another portion (3) works at a lower temperature or at a lower pressure. The separation effects are achieved because at least one third of one of the components of the mixtures changes its state during the change of temperature and pressure. The method is particularly appropriate for the separation of methane and argon in a synthesis circuit of an ammonia plant. The usual losses of hydrogen and ammonia are avoided. The method does not require any compressor, high pressure pump, or low temperature plant.