CAS: 55849-30-4; 5-Bromo-2-Ethoxypyridine

相似化合物

870521-31-6 13472-85-0 850142-79-9

上下游产品

CAS号624-28-2 2,5-二溴吡啶 | CAS号64-17-5 乙醇 | CAS号141-52-6 乙醇钠 | CAS号2678-54-8 1,1-二乙氧基乙烯 | CAS号114078-88-5 5-溴-1,2,3-三嗪 | CAS号1072-97-5 2-氨基-5-溴吡啶 | CAS号14529-53-4 2-乙氧基吡啶 | CAS号39856-50-3 5-溴-2-硝基吡啶 | CAS号52025-34-0 5-氨基-2-乙氧基吡啶 | CAS号612845-44-0 6-乙氧基-3-吡啶硼酸 | CAS号14529-53-4 2-乙氧基吡啶

2,5-二溴吡啶置于naoet体系中,用 乙醇 作为反应溶剂,化学反应生成 5-溴-2-乙氧基吡啶
参考文献:Alpha V Integrin Receptor Antagonists
标题:Alpha V Integrin Receptor Antagonists
摘要:本发明涉及新型咪唑烷酮衍生物及其合成,以及它们作为αv整合素受体拮抗剂的用途.更具体地说,本发明的化合物是αvβ3和/或αvβ5整合素受体的拮抗剂,可用于抑制骨吸收,治疗和预防骨质疏松症,抑制血管再狭窄,糖尿病视网膜病变,黄斑变性,血管反应生成,动脉粥样硬化,炎症,炎症性关节炎,病毒性疾病,癌症和转移性肿瘤生长.

专利信息

专利号:US-8742118-B2
优先权日:2011-10-27
标题 :Methods for preparing intermediates of perampanel
发明人：FONTANA FRANCESCO; STABILE PAOLO
权利人:F I S —FABBRICA ITALIANA SINT S P A
摘要:Methods for the synthesis of 2-alkoxy-5-(pyridin-2-yl)pyridine of formula I n nor salts thereof are provided.

专利号:US-2006025421-A1
优先权日:2004-06-25
标 题:Pyridyl piperazines for the treatment of CNS disorders
发明人：BRODNEY MICHAEL A
权利人:PFIZER
摘要:This invention is directed to compounds of Formula I and to pharmaceutical compositions comprising the compound of Formula I. n n where the dashed line represents an optional double bond; and where n is 1 or 2, and Ar 1 , Ar 2 , . . . and Z are as defined in the specification. The invention is also directed to a method of treating a disorder or condition that can be treated by altering serotonin-mediated neurotransmission, such as migraine, headache, cluster headache, anxiety, depression, etc. This invention is also directed to intermediates useful in the synthesis of compounds of Formula I.

专利号:US-6017926-A
优先权日:1997-12-17
标题 :Integrin receptor antagonists
发明人：ASKEW BEN C; COLEMAN PAUL J; DUGGAN MARK E; HALCZENKO WASYL; HUTCHINSON JOHN H; MEISSNER ROBERT S; PATANE MICHAEL A; WANG JIABING
权利人:MERCK & CO INC
摘要:The present invention relates to compounds and derivatives thereof, their synthesis, and their use as integrin receptor antagonists. More particularly, the compounds of the present invention are antagonists of the integrin receptors alpha v beta 3, alpha v beta 5 and/or alpha v beta 6 and are useful for inhibiting bone resorption, treating and preventing osteoporosis, and inhibiting vascular restenosis, diabetic retinopathy, macular degeneration, angiogenesis, atherosclerosis, inflammation, wound healing, viral disease, and tumor growth and metastasis.

专利号:US-6472403-B2
优先权日:2000-01-20
标 题 :αV integrin receptor antagonists
发明人：DUGGAN MARK E; HALCZENKO WASYL; HUTCHINSON JOHN H; LI AIWEN; MEISSNER ROBERT S; PERKINS JAMES J; STEELE THOMAS G; WANG JIABING; PATANE MICHAEL A
权利人:MERCK & CO INC
摘要:The present invention relates to novel imidazolidinone derivatives thereof, their synthesis, and their use as αv integrin receptor antagonists. More particularly, the compounds of the present invention are antagonists of the integrin receptors αvβ3 and/or αvβ5 and are useful for inhibiting bone resorption, treating and preventing osteoporosis, and inhibiting vascular restenosis, diabetic retinopathy, macular degeneration, angiogenesis, atherosclerosis, inflammation, inflammatory arthritis, viral disease, cancer, and metastatic tumor growth.

专利号:EP-1040111-B1
优先权日:1997-12-17
标 题:Integrin receptor antagonists
发明人：DUGGAN MARK E; MEISSNER ROBERT S; HUTCHINSON JOHN H; HALCZENKO WASYL; ASKEW BEN C; COLEMAN PAUL J; PATANE MICHAEL A; WANG JIABING; PERKINS JAMES J
权利人:MERCK & CO INC
摘要:The present invention relates to compounds and derivatives thereof, their synthesis, and their use as integrin receptor antagonists. More particularly, the compounds of the present invention are antagonists of the integrin receptors alpha v beta 3, alpha v beta 5 and/or alpha v beta 6 and are useful for inhibiting bone resorption, treating and preventing osteoporosis, and inhibiting vascular restenosis, diabetic retinopathy, macular degeneration, angiogenesis, atherosclerosis, inflammation, wound healing, viral disease, and tumor growth and metastasis.