CAS: 58846-77-8; (2R,3R,4S,5S,6R)-2-(Decyloxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol

该化合物是源自可再生碳水化合物和脂肪酒精来源的非离子表面活性剂,其特点是温和,生物降解性和低刺激潜力,适合个人护理,药物和生化研究的应用.该化合物展示了膜蛋白的溶解和稳定性,加强了其在清洁剂研究中的功能.其高化学稳定性和与广范围pH值的兼容性进一步有助于其配方的用途,需要温和而有效的表面活性剂. Decyl-β-D-甘蓝色片特别受到重视,因为它既能保持蛋白质完整性,又能提供明确的小鼠溶液,从而在敏感的生物化学应用中成为首选.

结构式图片

相似化合物

69984-73-2 29836-26-8 29781-80-4

上下游产品

CAS号2280-44-6 D-glucopyranose | CAS号112-30-1 正癸醇 | CAS号572-09-8 2,3,4,6-四乙酰氧基-a... | CAS号92052-29-4 2,3,4,6-四-O-乙酰基... | CAS号604-69-3 β-D-葡萄糖五乙酸酯 | CAS号81058-27-7 2,3,4,6-O-四特戊酰基... | CAS号225641-96-3 decyl 2,3,4,6-t... | CAS号25320-96-1 1-pentanol β-D-... | CAS号78617-12-6 庚基-β-D-吡喃葡萄糖苷 | CAS号492-61-5 β-D-葡萄糖 | CAS号112-30-1 正癸醇 | CAS号69984-73-2 壬基-Β-D-葡萄吡喃糖甙

合成工艺路线路线简述

    戊基beta-D-吡喃葡萄糖苷置于水体系中,用 水 作为反应溶剂,化学反应 168.0H,反应生成 (2R,3R,4S,5R,6R)-2-癸氧基-6-(羟基甲基)四氢吡喃-3,4,5-三醇
    参考文献:Significantly Improved Equilibrium Yield Of Long-Chain Alkyl Glucosides Via Reverse Hydrolysis In A Water-Poor System Using Cross-Linked Almond Meal As A Cheap And Robust Biocatalyst
    标题:Significantly Improved Equilibrium Yield Of Long-Chain Alkyl Glucosides Via Reverse Hydrolysis In A Water-Poor System Using Cross-Linked Almond Meal As A Cheap And Robust Biocatalyst
    摘要:An Array Of Ten Beta-D-Glueopyranosides With Varied Alkyl Chain Lengths Were Enzymatically Synthesized. It Was Found That For Longer Alkyl Chains A Lower Initial Rate And Final Yield Of Glucoside Was Obtained Except For Methyl Glucoside Because Of The Severe Toxicity Of Methanol To The Enzyme. From A Thermodynamics Point Of View,The Equilibrium Constant And Gibbs Free Energy Variation Of The Glucoside Syntheses Were Systematically Investigated. To Improve The Final Yields Of The Glucosides Containing Long Alkyl Chains The Equilibrium Of The Enzymatic Glucoside Synthesis Was Altered. The Equilibrium Yield Of Decyl Beta-D-Glucoside Increased From 1.9% To 6.1% When The Water Content Was Reduced From 10% To 5% (V/v) Using Tert-Butanol As A Cosolvent And 0.10 Mol/l Of Glucose As A Substrate. As For The Other Longer Alkyl Chain Glucosides,Heptyl Beta-D-Glucoside Was Found To Have Significant Surface Activity As Well.
    DOI:10.1016/s1872-2067(11)60333-1

    海关参考信息

    专利信息


    专利号:US-2001049117-A1
    优先权日:1998-08-20
    标 题 :Analogs of udp-murnac peptides, assays, kits and related methods of their use
    发明人:AXELROD HELENA R; BRANSTROM ARTHUR A
    摘要:General compositions and methods for detecting Lipid I, Lipid II and peptidoglycan synthesis is disclosed. A method of screening for potential antibacterial agents is provided which requires bacterial membrane preparations or enriched enzyme preparations including at least one bacterial enzyme involved in the synthesis of Lipid I from UDP-MurNAc pentapeptide and undecaprenyl phosphate, at least one bacterial enzyme involved in the synthesis of Lipid II from Lipid I and UDP-GlcNAc and one or more bacterial enzymes involved in the further processing of Lipid II toward the downstream synthesis of peptidoglycan. The methods disclosed herein further provides a labeled UDP-MurNAc-peptide capable of serving as a substrate for a bacterial enzyme involved in the synthesis of Lipid I and a labeled UDP-GlcNAc capable of serving as a substrate for a bacterial enzyme involved in the synthesis of Lipid II. Conditions for further processing of Lipid II toward the downstream synthesis of peptidoglycan are also discribed.

    专利号:WO-2024130393-A1
    优先权日:2022-12-21
    标 题 :Nanoparticle and method of synthesis thereof
    发明人:MOSKOVCHENKO SVITLANA
    权利人:MOSKOVCHENKO SVITLANA
    摘要:The present technology relates to nanoparticles, compositions comprising said nanoparticles, and methods of synthesis of said nanoparticles; wherein the nanoparticles comprise a metal nanoparticle core, a first coating of amphiphilic molecules, and a second coating of essential oil, essential oil primary constituent, or both, which combine the antimicrobial properties of metal nanoparticles, amphiphilic molecules, and essential oil or essential oil primary constituents.

    专利号:EP-1721601-A1
    优先权日:2005-05-11
    标 题 :Use of taurine for enhancing lipid synthesis in the epidermis
    发明人:DOERING THOMAS; WALDMANN-LAUE MARIANNE; WADLE ARMIN; ANDERHEGGEN BERND
    权利人:HENKEL KGAA
    摘要:The present invention is the use of taurine for stimulating the epidermal synthesis of barrier lipids.

    专利号:US-2024010511-A1
    优先权日:2019-05-02
    标 题 :Methods and compositions for synthesis of phosphor and its incorporation in a polymer matrix for light conversion
    发明人:SAHI SUNIL
    权利人:SOLGO INC; SOLGRO INC
    摘要:The invention relates to methods and compositions for synthesizing a phosphor and preparing a surface-modified phosphor comprising a phosphor, a silica, and a silane, and articles comprising same. The invention also relates to a method of dispersion of the disclosed surface-modified phosphor with a blue emitting agent in a polymer matrix and uses thereof.

    专利号:WO-2020225409-A1
    优先权日:2019-05-09
    标 题:Process for a continuous synthesis of a cha zeolitic material from an emulsion
    发明人:SCHREYER HANNAH; PARVULESCU ANDREI-NICOLAE; MUELLER ULRICH; OKUBO TATSUYA; WAKIHARA TORU; IYOKI KENTA; LIU ZHENDONG
    权利人:BASF SE; UNIV TOKYO
    摘要:The present invention relates to a continuous process for preparing a zeolitic material comprising YO 2 and optionally X 2 O 3 in this its framework structure, wherein Y is a tetravalent element and X is a trivalent element, said process comprising. (i) providing a flow reactor comprising a reaction zone; (ii) continuously passing a reactant stream through the reaction zone according to (i), wherein the reactant stream comprises a reactant mixture comprising a non-polar liquid solvent system, one or more emulsifiers, and a mixture of one or more sources of YO 2 , optionally one or more sources of X 2 O 3 , seed crystals, a polar protic liquid solvent system, and one or more tetraalkylammonium cation containing compounds as structure directing agent; (iii) subjecting the reactant stream to crystallization conditions in the reaction zone and removing a product stream from the reaction zone, wherein the product stream comprises the zeolitic material. Furthermore, the invention further to a zeolitic material obtainable and/or obtained according to the inventive process, as well as to the use of said zeolitic material.

    专利号:WO-2020225419-A1
    优先权日:2019-05-09
    标 题 :One-pot synthesis of metal-exchanged zeolitic materials
    发明人:LIZANDARA PUEYO CARLOS; STREGE STEFAN; MASSONNE KLEMENS; PARVULESCU ANDREI-NICOLAE; MUELLER ULRICH; MUELHEIMS KERSTIN; SCHUNK STEPHAN A; SCHAEFER SEBASTIAN; GORDILLO ALVARO; RUETZ ROGER; MUELLER ROBERT
    权利人:BASF SE
    摘要:The present invention relates to a process for the preparation of a metal-exchanged zeolitic material comprising SiO 2 and X 2 O 3 in its framework structure, wherein X is a trivalent element, comprising (1) preparing a first mixture comprising one or more nonpolar organic solvents, one or more polar protic solvents, one or more organotemplates as structure directing agents, one or more bases, and optionally one or more emulsifiers; (2) emulsifying said mixture; (3) adding one or more sources of SiO 2 to the emulsified mixture; (4) preparing a second mixture comprising one or more nonpolar organic solvents; (5) adding one or more sources of a metal M to the second mixture; (6) adding the second mixture to the first mixture; (7) heating the mixture obtained in (6) for crystallizing, and wherein the first mixture prepared in (1) and/or the second mixture prepared in (4) further comprises one or more sources of X 2 O 3 . Further, the present invention relates to a metal-exchanged zeolitic material and use thereof.
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    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Bai H, Tam I, Yu J. Contact Allergens in Top-Selling Textile-care Products. Dermatitis. 2020 Jan 3. doi: 10.1097/DER.0000000000000566. [Epub ahead of print] doi: 10.1111/cod.13186. Epub 2018 Dec 21. doi: 10.1166/jnn.2019.15900. doi: 10.18388/abp.2018_2554. Epub 2018 Sep 15. doi: 10.1111/cod.13026. Epub 2018 May 17. Erratum in: Contact Dermatitis. 2019 Jan;80(1):76. doi: 10.1515/acph-2017-0036. doi: 10.1111/cod.12852. doi: 10.1097/DER.0000000000000327. doi: 10.1007/s11743-016-1887-7. Epub 2016 Oct 6.
    11: Loranger C, Alfalah M, Ferrier Le Bouedec MC, Sasseville D. Alkyl Glucosides in Contact Dermatitis. Dermatitis. 2017 Jan/Feb;28(1):5-13. doi: 10.1097/DER.0000000000000240. doi: 10.1097/DER.0000000000000234. doi: 10.1248/bpb.b15-00961. doi: 10.1159/000441040. Epub 2015 Nov 6. doi: 10.3109/15569527.2015.1055495. Epub 2015 Jun 22. doi: 10.1111/cod.12417. Epub 2015 May 11. doi: 10.1111/cod.12324. Epub 2014 Dec 18. doi: 10.1111/cod.12159. doi: 10.1111/cod.12154.

    合成参考文献


    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
    摘要:International Journal of Toxicology 32(Suppl. 3):22-48, 2013
    参考文献:10.1111/j.1600-0536.2009.01680.x
    摘要:Andrade P, Gonçalo M, Figueiredo A. Allergic Contact Dermatitis to Decyl Glucoside in Tinosorb M®. Contact Dermatitis. 2010 Jan 29;62(2):119–20. doi: 10.1111/j.1600-0536.2009.01680.x.
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