CAS: 67-07-2; 2-(1-Methyl-3-Phosphonoguanidino)Acetic Acid

上下游产品

N-(diphenoxyphosphoryl-carbamimidoyl)-N-methyl-glycine benzyl esterN-(diphenoxyphosphoryl-carbamimidoyl)-N-methyl-glycine benzyl ester phosphoenolpyruvic acid Creatinine 1-methyl-4-nitrosobenzeneCreatinine creatinine Creatinine ATP

肌酸置于磷酸,尿素体系中,化学反应 2.0H,反应生成 磷酸肌酸
参考文献:磷氮型阻燃剂的制备及其在耐老化阻燃复合材料中的应用
标题:磷氮型阻燃剂的制备及其在耐老化阻燃复合材料中的应用
摘要:本发明公开了一种磷氮型阻燃剂的制备及其在耐老化阻燃复合材料中的应用.混合一水肌酸,尿素和磷酸溶液,油浴搅拌反应,自然冷却至室温,得反应后溶液;反应后溶液倒入无水乙醇中,产生絮状产物,多次离心洗涤,干燥,制得磷氮型阻燃剂.聚乙烯醇溶于去离子水中,得聚乙烯醇溶液;混合荧光粉,一水肌酸和聚乙烯醇溶液,搅拌均匀,得分散体系;室温下干燥,制得耐老化阻燃聚乙烯醇复合材料.该制备方法使用的原料便宜,工艺简单,适合大规模的工业化生产.制得的耐老化阻燃聚乙烯醇复合材料不改变原有聚乙烯醇的透明度,能够更广泛的应用于装饰领域.

专利信息

专利号:US-2012190064-A1
优先权日:2004-10-01
标题 :Feeding buffers, systems, and methods for in vitro synthesis of biomolecules
发明人：KUDLICKI WIESLAW ANTONI; KEPPETIPOLA SHIRANTHI; FLETCHER JULIA; GETBEHEAD ASHLEY ELAINE; KATZEN FEDERICO; VOZZA-BROWN LAURA
权利人:KUDLICKI WIESLAW ANTONI; KEPPETIPOLA SHIRANTHI; FLETCHER JULIA; GETBEHEAD ASHLEY ELAINE; KATZEN FEDERICO; VOZZA-BROWN LAURA; LIFE TECHNOLOGIES CORP
摘要:Compositions, methods and kits for in vitro systems for synthesis of biomolecules such as polypeptides, are provided herein. Cell extracts that provide enhanced yields of soluble proteins using in vitro protein synthesis methods are provided. The invention also includes methods for producing high yields of proteins by the addition of a feeding solution that includes amino acids and an energy source to an ongoing in vitro synthesis system. The invention also includes methods of using a high-yield in vitro synthesis system to produce large quantities of proteins with incorporated labeled amino acids for analysis by methods such as by NMR. The invention further includes vectors for enhanced production of proteins from nucleic acid templates using in vitro synthesis systems.

专利号:US-6168931-B1
优先权日:1999-03-17
标题 :Enhanced in vitro synthesis of biological macromolecules using a novel ATP regeneration system
发明人：SWARTZ JAMES R; KIM DONG-MYUNG
权利人:UNIV LELAND STANFORD JUNIOR
摘要:Compositions and methods are provided for the enhanced in vitro synthesis of biological molecules where ATP is required for synthesis. Of particular interest is the synthesis of polymers, e.g. nucleic acids, polypeptides, and complex carbohydrates. A homeostatic system is used for production of ATP, where the required high energy phosphate bonds are generated in situ, e.g. through coupling with an oxidation reaction. The homeostatic energy source will typically lack high energy phosphate bonds itself, and will therefore utilize free phosphate in the reaction mix during generation of ATP. Since inorganic phosphate can be an inhibitory by-product of synthesis, the period of time when synthesis is maintained in vitro can be extended. The homeostatic energy source is provided in combination with an enzyme that catalyzes the creation of high energy phosphate bonds and with an enzyme that can use that high energy phosphate bond to regenerate ATP.

专利号:US-6783957-B1
优先权日:1999-03-25
标题:Method for synthesis of polypeptides in cell-free systems
发明人：BIRYUKOV SERGEY VLADIMIROVICH; SIMONENKO PETER NIKOLAEVICH; SHIROKOV VLADIMIR ANATOLIEVICH; SPIRIN ALEXANDER SERGEYEVICH
权利人:ROCHE DIAGNOSTICS GMBH; INST OF PROTEIN RES
摘要:The method of polypeptide synthesis in eukaryotic or porkaryotic cell-free systems based on a modified verion of synthesis in the continuous flow or continuous exchange modes when, in addition to input into the reaction mixture of components maintaining the synthesis and removal from the reaction mixture of low molecular weight components inhibiting the synthesis, the concentration of at least one of the components selected from the group consisting of Mg 2+ , K + , NTP, polyamines or their combinations determining the productivity of the synthesis is continuously changed within the given range of concentrations, while the concentrations of the other components are maintained constant.

专利号:US-2005153390-A1
优先权日:2002-05-14
标 题 :Lyophilized preparation for synthesis of cell-free protein
发明人：ENDO YAETA; OGASAWARA TOMIO
权利人:CELLFREE SCIENCES CO LTD
摘要:Lyophilized preparations from cell extract for use in cell-free protein, which exhibit an activity for protein synthesis being in no way inferior to that exhibited in low-temperature storage; and a method of utilizing the same. In particular, preparations are formed by performing lyophilization after reducing the concentration of deliquescent substances in a solution containing cell extract for synthesis of cell-free protein to a level not detrimental to the quality of preparations after lyophilization.

专利号:US-6994986-B2
优先权日:1999-03-17
标 题:In vitro synthesis of polypeptides by optimizing amino acid metabolism
发明人：SWARTZ JAMES ROBERT; KIM DONG-MYUNG
权利人:UNIV LELAND STANFORD JUNIOR
摘要:Compositions and methods are provided for the enhanced in vitro synthesis of polypeptides. In order to improve the performance of in vitro protein synthesis reactions, metabolic inhibitors, or manipulation of a source organism, is used to diminish or avoid the action of enzymes responsible for undesirable amino acids production or depletion. A homeostatic system may be used for production of ATP, where the required high energy phosphate bonds are generated in situ, e.g. through coupling with an oxidation reaction. The homeostatic energy source will typically lack high energy phosphate bonds itself, and will therefore utilize free phosphate in the reaction mix during generation of ATP. The homeostatic energy source is provided in combination with an enzyme that catalyzes the creation of high energy phosphate bonds and with an enzyme that can use that high energy phosphate bond to regenerate ATP.

专利号:EP-1525305-B1
优先权日:2002-08-02
标题:Methods and compositions for in vitro synthesis of proteins in a cell-free system enriched with atp-sulfurylase
发明人：RYABOVA LYUBOV; MASSON JEAN-MICHEL
权利人:PROTEUS
摘要:The present invention provides methods and composition for enhancing in vitro synthesis of biological macromolecules in a cell-free system where ATP is required as a primary energy source, wherein said cell-free system is enriched with ATP-sulfurylase The invention relates also to as cell-free systems and cell-free extracts enriched with ATP-sulfurylase for enhancing in vitro synthesis of any biological macromolecules.