CAS: 74974-54-2; 2-Chloro-1,1,1-Trimethoxyethane

相似化合物

51076-95-0 78-39-7 74974-54-2

上下游产品

CAS号1445-45-0 原乙酸三甲酯 | CAS号96-34-4 氯乙酸甲酯 | CAS号149-73-5 原甲酸三甲酯 | CAS号67-56-1 甲醇 | CAS号70737-12-1 2-氯乙酰亚胺甲酯 盐酸盐 | CAS号110704-19-3 5-氯-2-(氯甲基)-1,3-苯并噻唑 | CAS号110704-48-8 5-Bromo-2-(chlo... | CAS号37908-98-8 3-氯-4-甲氧基苯甲酸甲酯 | CAS号33575-83-6 2-氯甲基-5-苯基-[1,3... | CAS号41014-44-2 2-氯甲基-5-甲基-1,3-苯并噁唑 | CAS号221638-74-0 2-(Chloromethyl... | CAS号24023-72-1 2-氯甲基-5-(2-氯苯基)... | CAS号24068-15-3 2-(氯甲基)-5-(4-氯苯... | CAS号252742-72-6 5-氯甲基-2,4 -二氢[ ... | CAS号721428-34-8 5-(氯甲基)-3-(4-氟苯...

原乙酸三甲酯置于sodium Methylate,氯体系中,化学反应 4.0H,以76%的收率获得产物2-氯-1,1,1-三甲氧基乙烷
参考文献:Verfahren Zur Herstellung Von 2-Chloro-1,1,1-Trialkoxyethan
标题:Verfahren Zur Herstellung Von 2-Chloro-1,1,1-Trialkoxyethan
摘要:该发明涉及一种通过在醇的存在下,将1,1,1-三烷氧基乙烷(I)(正乙酸酯酸酯)与氯反应而制备2-氯-1,1,1-三烷氧基乙烷(II)(单氯乙酸正乙酯)的方法,其中还使用催化剂基量的碱.

专利信息

专利号:US-2004152905-A1
优先权日:2003-01-31
标题:Universal building blocks and support media for synthesis of oligonucleotides and their analogs
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and chemically modified oligonucleotide analogs, are provided. In addition, methods for functionalization of a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-11512097-B2
优先权日:2019-11-25
标题 :Heterocyclic compounds as Delta-5 desaturase inhibitors and methods of use
发明人：ALLEN JENNIFER R; BELTRANI MICHELA; BOURBEAU MATTHEW P; DAMYANOVA TEODORA P; LINGARD IAIN; MINATTI ANA E; VINCETTI PAOLO
权利人:AMGEN INC
摘要:The present disclosure provides compounds useful for the inhibition of Delta-5 Desaturase (“D5Dâ€?). The compounds have a general Formula I n nwherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a metabolic or cardiovascular disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

专利号:US-9493461-B2
优先权日:2013-02-07
标 题 :Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis C
发明人：DAI XING; LIU HONG; PALANI ANANDAN; HE SHUWEN; LAI ZHONG; NARGUND RAVI; MARCANTONIO KAREN; XIAO DONG; BROCKUNIER LINDA L; ZORN NICOLAS; DANG QUN; PENG XUANJIA; LI PENG
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula I that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-2023364251-A1
优先权日:2020-08-06
标 题:Methods for the synthesis of protein-drug conjugates
发明人：BORCHARDT ALLEN; HUGHES ROBERT MICHAEL
权利人:CIDARA THERAPEUTICS INC
摘要:The present invention relates to intermediates and methods for synthesizing protein-drug conjugates that can be used for the treatment of diseases and related conditions.

专利号:US-8772301-B2
优先权日:2009-12-18
标题 :Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof
发明人：HARDY LARRY WENDELL; HEFFERNAN MICHELE L R; WU FRANK XINHE; SPEAR KERRY L; SARASWAT LAKSHMI D
权利人:HARDY LARRY WENDELL; HEFFERNAN MICHELE L R; WU FRANK XINHE; SPEAR KERRY L; SARASWAT LAKSHMI D; SUNOVION PHARMACEUTICALS INC
摘要:Provided herein are compounds and methods of synthesis thereof. The compounds set forth herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, neurodegenerative disorders, neuropsychiatric disorders, disorders of cognition, learning or memory, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds set forth herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.

专利号:TW-202220698-A
优先权日:2020-08-06
标题:Methods for the synthesis of protein-drug conjugates