CAS: 81012-94-4; 2-Chloroadenosine Hemihydrate

专利信息

专利号:US-7371852-B2
优先权日:2003-01-22
标 题 :Alkyl-linked nucleotide compositions
发明人：HARDEMAN KLASS P; HALL STEVEN E; WARE ROY W; HINKLEY LINDSAY A; JENKS MATTHEW G
权利人:SERENEX INC
摘要:Alkyl-linked nucleotide non-homogeneous solid supports and nucleotide affinity media comprising an alkyl-linked nucleotide are provided. The linker is generally a hydrophobic linker that can be a 3, 4, 5, 6, 7, 8, 9, 10, or a longer carbon chain. Also included in the invention are methods for synthesis of an alkyl-linked nucleotide, nucleotide affinity media and methods of use thereof for affinity chromatography and screening methods.

专利号:US-RE47301-E
优先权日:2006-02-03
标题 :Process for preparing an A2A-adenosine receptor agonist and its polymorphs
发明人：ZABLOCKI JEFF; ELZEIN ELFATIH; SEEMAYER ROBERT; LEMONS TRAVIS
权利人:GILEAD SCIENCES INC
摘要:Disclosed is a synthesis suitable for large scale manufacture of an A 2A -adenosine receptor agonist, and also relates to polymorphs of that compound, and to methods of isolating a specific polymorph.