CAS: 19362-77-7; 4,4'-Thiobisbenzenethiol

该化合物是有机硫化合物,其特征是联苯结构中存在两个硫醇(SH)组,在室温中一般是固体,由于硫醇功能组而闻名其强味,在有机溶剂中溶解,但溶解程度有限;硫醇组的存在具有重要的再活动性,允许其参与各种化学反应,包括氧化和形成硫化物. 4,4'-Thiobisbenzenethil经常用于材料科学和有机合成,特别是在聚合物的研制中,以及作为各种化学过程的一种联动剂.此外,它可以作为协调化学的悬浮剂,与过渡性金属形成复杂.在处理该化合物时,应当注意安全防范,因为硫醇可能是有毒的,并且会刺激皮肤和呼吸系统.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号3119-65-1 4,4'-Thiobis(be... | CAS号133838-69-4 4,4'-sulfanediy... | CAS号7647-01-0 盐酸 | CAS号152419-82-4 1-(2-chloroethy... | CAS号125877-23-8 1-methylsulfany...

合成工艺路线路线简述

  • 合成目标产物 4,4'-Thiodibenzenethiol 主要起始原料 Diphenyl Sulfide
  • (文献来源)合成步骤主要原料 Diphenyl Sulfide
4,4'-Bis(Chlorosulfonyl)Diphenyl Sulfide置于盐酸,水,锌体系中,用 甲苯 用作溶剂,化学反应 2.0H,以93%的收率获得4'4-二巯基二苯硫醚
参考文献:Alov; Nikiforov; Novikov,Russian Journal Of Organic Chemistry,1998,Vol. 34,# 8,P. 1160-1164
标题:Alov; Nikiforov; Novikov,Russian Journal Of Organic Chemistry,1998,Vol. 34,# 8,P. 1160-1164

海关参考信息

专利信息


专利号:US-11155540-B2
优先权日:2017-06-14
标 题 :Sulfurized benzoxazine for use in the synthesis of a polybenzoxazine
发明人:FEDURCO MILAN; RIBEZZO MARCO
权利人:MICHELIN & CIE
摘要:A sulfurized benzoxazine compound, which is usable for the synthesis of a polybenzoxazin, corresponds to formula (A): n nin which: each benzene nucleus of the two oxazine rings bears at least one radical denoted as “Gâ€?; the two oxazine rings are connected together via a central aromatic group, the benzene ring of which bears one, two, three or four groups of formula —S x —R in which “xâ€? is an integer from 1 to 8 and R represents hydrogen or a hydrocarbon-based group including 1 to 10 carbon atoms and optionally a heteroatom chosen from O, S, N and P; and the at least two radicals G, which may be identical or different, are chosen from various groups.

专利号:US-10995076-B2
优先权日:2017-05-24
标 题:Halogenated benzoxazine for use in the synthesis of polybenzoxazine
发明人:FEDURCO MILAN; RIBEZZO MARCO
权利人:MICHELIN & CIE
摘要:A halogenated benzoxazine compound, which can be used in particular as monomer in the synthesis of polybenzoxazine, corresponds to the formula (the symbol Hal representing at least one halogen): n nin which: each benzene nucleus bears at least one halogen; R 1 and R 2 , which are identical or different, represent hydrogen or an alkyl comprising from 1 to 8 carbon atoms; “x 1 â€? and “x 2 â€?, which are identical or different, are integers equal to or greater than 1; “x 3 â€? is an integer equal to or greater than 1; and X is a heteroatom chosen from O and S.

专利号:US-10975044-B2
优先权日:2017-05-24
标题:Halogenated benzoxazine for use in the synthesis of polybenzoxazine
发明人:FEDURCO MILAN; RIBEZZO MARCO
权利人:MICHELIN & CIE
摘要:A halogenated benzoxazine compound, which can be used in particular as monomer in the synthesis of polybenzoxazine, corresponds to the formula: n nin which: each benzene nucleus of the two oxazine rings bears at least one halogen (represented by the symbol Hal), in particular bromine, chlorine or fluorine; and Z 1 and Z 2 , which are identical or different, represent an aliphatic, at least divalent, bonding group comprising at least one carbon atom and optionally at least one heteroatom chosen from O, S, N and P.

专利号:US-2009111737-A1
优先权日:1999-05-24
标题:Novel antibacterial agents
发明人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

专利号:US-2023159678-A1
优先权日:2020-06-19
标题:Methods of polymerization with aromatic thiol initiators
发明人:BOWMAN CHRISTOPHER N; LOVE DILLON
权利人:UNIV COLORADO REGENTS
摘要:Provided herein are methods of using aryl thiols as photoinitiators. The thiol compounds are useful as oxygen insen-sitive photoinitiators for applications such as bulk polymerizations and for specialty polymer synthesis by preparing aromatic thiol functionalized macroinitiators.

专利号:US-8609801-B2
优先权日:2011-09-29
标题:Polymers and copolymers containing 2H-benzimidazol-2-one moieties
发明人:HAY ALLAN S; MIR AABID; HLIL ANTISAR R; MATSUMURA SUMIKO
权利人:UNIV MCGILL; UNIV MCGILL
摘要:Polymers and copolymers containing 1H-benzo[d]imidazol-2(3H)-one units have been synthesized under conditions generally used for the synthesis of poly(aryl ether)s. 1H- n nbenzo[d]imidazol-2(3H)-one behaves like a biphenol in the polymerization reaction.n n The soluble homopolymer has a very high glass transition temperature (348° C.), good thermal stability, and forms flexible transparent films. Because of the low molecular weight (134.14) of the benzoimidazolone monomer in the copolymer formed with 4,4′-biphenol that contains 30 mole % of the benzimidazolone unit, only 8.9 weight % is required to raise the Tg of the poly(arlyl ether)sulfone from 220° C. to 269° C.
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合成参考文献


参考文献:10.1055/s-0031-1290262
摘要:Highly Refractive Transparent Polymers by Design. Synfacts. 2012 Feb 20;8(03):0274. doi: 10.1055/s-0031-1290262.
参考文献:10.1007/978-3-030-95660-8_34
摘要:Radecki J, Radecka H. Voltammetric Biosensors in Bioanalysis. 2022. In: Handbook of Bioanalytics.
参考文献:10.1055/s-0040-1719932
摘要:Swager TM, Etkind SI, Ichii S, Romero NA. Thiapillar[6]arene: Synthesis, Functionalization, and Properties. Synlett. 2022 Jun 21;33(15):1532–8. doi: 10.1055/s-0040-1719932.
参考文献:10.1038/s41428-023-00778-5
摘要:Hirosawa Y, Kamitani T, Imoto H, Naka K. Thermal and mechanical behaviors of beads-on-string-shaped poly(azomethine)s based on their linker structures. Polym J. 2023 Apr 14;55(8):849–58. doi: 10.1038/s41428-023-00778-5.
参考文献:10.1007/s11426-023-1771-6
摘要:Liu X, Zhou J, Liu S, Zhao J. Design and synthesis of thiol-terminated imidothioether oligomer as thermally latent hardener and modifier for high-performance epoxy/thiol thermosets. Sci. China Chem. 2023 Nov 14;67(2):632–41. doi: 10.1007/s11426-023-1771-6.
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