CAS: 22255-40-9; (1S,4As,6S,7R,7As)-6-Hydroxy-7-Methyl-1-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)-1,4A,5,6,7,7A-Hexahydrocyclopenta[c]Pyran-4-Carboxylic Acid

上下游产品

Ligustrinoside loganin (1S,4aS,6S,7R,7aS)-7-Methyl-6-[(E)-(3-phenyl-acryloyl)oxy]-1-((2S,3R,4S,5R,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-1,4a,5,6,7,7a-hexahydro-cyclopenta[c]pyran-4-carboxylic acid bis-desoxy-dihydro-monotropeinloganin alyxialactone 4-epi-Alyxialactone 2',3',4',6',7-penta-O-acetylloganin

马钱子苷置于barium Dihydroxide体系中,用 甲醇 用作溶剂,化学反应生成马钱苷酸
参考文献:Modified Iridoid Glycosides As Anti-Implantation Agents
标题:Modified Iridoid Glycosides As Anti-Implantation Agents
摘要:Structural Modifications In Iridoid Glycosides And Evaluation Of Their Efficacy On Adhering Capability (In Vitro) Of Immature Hamster Uterine Epithelial Cells To The Substratum Have Been Studied. Out Of 31,Eight Compounds In Vitro,Five Compounds In Utero And Two In Vivo Showed Adhesion/implantation Preventing Activity,Respectively. The Results Provide An Indication For Further Exploration In The Line Of Development Of Anti-Adhesive Agents. (C) 2001 Published By Elsevier Science Ltd.
Doi:10.1016/s0968-0896(01)00105-5

专利信息

专利号:US-2025092433-A1
优先权日:2023-09-20
标 题:Polypeptides for use in the synthesis of kratom alkaloids
发明人：CASARETTO JOSE; AKTAR TARIQ A; ROTHSTEIN STEVEN; SOUBEYRAND ERIC
权利人:MITRADYNE CORP
摘要:Described herein are polypeptides encoding enzymes for the synthesis of monoterpene indole alkaloids. For example, the polypeptide comprises or consists of the sequence of SEQ ID NO: 1-68, or a variant thereof having at least 80% sequence identity to SEQ ID NO: 1-68, or a fragment of the polypeptide, or the variant thereof.

专利号:US-2022356497-A1
优先权日:2019-06-26
标 题 :Compositions and methods for synthesis of terpenoids
发明人：DE KOK STEFAN; LAU WARREN; MCSORLEY FERN; MEYER HERMANN-JOSEF; SERBER ZACH; WAWRZYN GRAYSON
权利人:ZYMERGEN INC
摘要:The disclosure relates to the biosynthesis of terpenoids, such as, for example, geraniol and derivatives thereof, using genetic engineering. In particular, the disclosure relates to the biosynthesis of nepetalactol, nepetalactone, dihydronepetalactone, and derivatives thereof. The disclosure provides recombinant cells genetically engineered to produce high levels of nepetalactol, nepetalactone and/or dihydronepetalactone. The disclosure also provides methods of producing nepetalactol, nepetalactone and dihydronepetalactone using cell-based systems as well as cell-free systems.

专利号:EP-4538367-A2
优先权日:2023-09-20
标 题:Polypeptides for use in the synthesis of kratom alkaloids

专利号:WO-2020264400-A2
优先权日:2019-06-26
标题 :Compositions and methods for synthesis of terpenoids

专利号:US-11427842-B2
优先权日:2018-03-16
标题 :Method and means for manufacturing terpene indole alkaloids
发明人：O'CONNOR SARAH; CAPUTI LORENZO; PAYNE RICHARD; FRANKE JAKOB; FARROW SCOTT
权利人:INNES JOHN CENTRE
摘要:The complex chemistry underlying the extensive transformations involved in terpene indole alkaloid synthesis makes identification of the biosynthetic genes challenging. The present invention relates to methods for producing a terpene indole alkaloid derivative, comprising the steps of: (1) providing a terpene indole alkaloid; and (2) providing a first enzyme termed “Precondylocarpine Acetate Synthaseâ€? (PAS) or a functional variant or homologue thereof; and/or a second enzyme termed “Dehydroprecondylocarpine Acetate Synthaseâ€? (DPAS) or a functional variant or homologue thereof, and optionally providing further identified enzymes involved in this pathway. The invention also encompasses related kits, enzymes, expression vectors, host cells and plants.