CAS: 32085-88-4; 3,5-Difluorobenzaldehyde

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CAS号64248-63-1 3,5-二氟苯甲腈 | CAS号79538-20-8 3,5-二氟苄醇 | CAS号461-96-1 1-溴-3,5-二氟苯 | CAS号367-25-9 2,4-二氟苯胺 | CAS号101471-20-9 2-溴-4,6-二氟苯胺氢溴酸 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号62351-47-7 3,5-二氟苯基溴化镁 | CAS号93-61-8 N-甲基甲酰苯胺 | CAS号127598-81-6 N-(3,5-difluoro... | CAS号433939-88-9 2,6-二氟-4-醛基苯氰 | CAS号84315-24-2 3-(3,5-二氟苯基)丙酸 | CAS号84315-23-1 3,5-二氟苯乙烯酸 | CAS号84315-25-3 5,7-二氟-1-茚酮 | CAS号79538-20-8 3,5-二氟苄醇 | CAS号583-05-1 1-苯基-1,4-戊二酮 | CAS号1016683-83-2 5-(3,5-Difluoro... | CAS号132741-31-2 3,5-二氟扁桃酸 | CAS号132980-99-5 3,5-二氟苯甲酰胺 | CAS号1241679-50-4 (3S)-3-amino-3-...

1-溴-3,5-二氟苯置于盐酸体系中,用 四氢呋喃,N,N-二甲基甲酰胺 用作溶剂,化学反应生成3,5-二氟苯甲醛
参考文献:Fluorine-Substituted-4-Alkenylbenzoic Acid And Derivatives Thereof,And Nematic Liquid Crystal Composition Containing Cyanophenyl Benzoate Derivatives And Liquid Crystal Display System Using The Same
标题:Fluorine-Substituted-4-Alkenylbenzoic Acid And Derivatives Thereof,And Nematic Liquid Crystal Composition Containing Cyanophenyl Benzoate Derivatives And Liquid Crystal Display System Using The Same
摘要:本文揭示了一种新型液晶化合物,一种向列型液晶组合物以及使用该组合物的液晶显示系统.该液晶化合物由通式(I)表示:其中r代表氢原子或具有1至7个碳原子的直链烷基基团,X,Y和z分别代表氢原子或氟原子.本发明的向列型液晶组合物即使在少量添加的情况下也能根据所需目的提供液晶材料,而不会破坏其他特性.

专利信息

专利号:US-8202985-B2
优先权日:2005-10-31
标 题:Monomer compositions for the synthesis of polynucleotides, methods of synthesis, and methods of deprotection
发明人：DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINO; CARUTHERS MARVIN H
权利人:DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINO; CARUTHERS MARVIN H; AGILENT TECHNOLOGIES INC; UNIV COLORADO
摘要:Nucleotide monomers, polynucleotides, methods of making each, and methods of deprotecting each, are disclosed. An embodiment of the nucleotide monomer, among others, includes a nucleotide monomer having a heterobase protecting group selected from structures I through III as described herein. An embodiment of the polynucleotide, among others, includes a plurality of nucleotide moieties having a heterobase protecting group selected from one of structures I through III as described herein.

专利号:US-7759471-B2
优先权日:2005-10-31
标题 :Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection
发明人：DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINE; CARUTHERS MARVIN H
权利人:AGILENT TECHNOLOGIES INC; UNIV COLORADO
摘要:Nucleotide monomers, polynucleotides, methods of making each, methods of deprotecting each, and the like are disclosed herein.

专利号:US-2009156465-A1
优先权日:2005-12-30
标题:Derivatives of beta-amino acid as dipeptidyl peptidase-iv inhibitors
发明人：SATTIGERI JITENDRA A; AHMED SHAHADAT; ANDAPPAN MURUGAIAH M S; SETHI SACHIN; SHARMA LALIMA; PAL CHANCHAL KUMAR; KANDALKAR SACHIN RAMESH; MAHAJAN DIPAK C; KISHORE KAUSHAL; BHATIA SUMATI; GADHAVE ANIL G; BANSAL VINAY S; DAVIS JOSEPH ALEXANAND
权利人:SATTIGERI JITENDRA A; AHMED SHAHADAT; ANDAPPAN MURUGAIAH M S; SETHI SACHIN; SHARMA LALIMA; PAL CHANCHAL KUMAR; KANDALKAR SACHIN RAMESH; MAHAJAN DIPAK C; KISHORE KAUSHAL; BHATIA SUMATI; GADHAVE ANIL G; BANSAL VINAY S; DAVIS JOSEPH ALEXANAND
摘要:The present invention relates to β-amino acid derivatives as dipeptidyl peptidase-IV inhibitors and the processes for the synthesis of the same. This invention also relates to pharmacological compositions containing the compounds of the present invention, and methods of treating diabetes, especially type 2 diabetes, as well as prediabetes, diabetic dyslipidemia, metabolic acidosis, ketosis, satiety disorders, and obesity. These inhibitors can also be used to treat conditions manifested by a variety of metabolic, neurological, anti-inflammatory, and autoimmune disorders like inflammatory disease, multiple sclerosis, rheumatoid arthritis; viral, cancer and gastrointestinal disorders. The compounds of this invention can also be used for treatment of infertility arising due to polycystic ovary syndrome.

专利号:US-2005192265-A1
优先权日:2003-03-20
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:WO-9967219-A1
优先权日:1998-06-22
标 题:Compounds for inhibiting beta-amyloid peptide release and/or its synthesis
发明人：AUDIA JAMES E; PORTER WARREN J; THOMPSON RICHARD C; WILKIE STEPHEN C; STACK DOUGLAS R; SHI QING
权利人:ELAN PHARM INC; LILLY CO ELI; AUDIA JAMES E; PORTER WARREN J; THOMPSON RICHARD C; WILKIE STEPHEN C; STACK DOUGLAS R; SHI QING
摘要:Compounds of formula (I), wherein W is a cyclic group of the type (2); (3); Y is represented by the formula (II); these compounds inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-6774125-B2
优先权日:1998-06-22
标 题:Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：AUDIA JAMES E; THOMPSON RICHARD C; WILKIE STEPHEN C; BRITTON THOMAS C; PORTER WARREN J; HUFFMAN GEORGE W; LATIMER LEE H
权利人:ELAN PHARM INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.