CAS: 6393-56-2; Magnesium,Pentane,Chloride

该化合物是一种Grignard试剂,是一种有机磁性化合物,经常用于有机合成;它含有一种聚乙烯(五碳烷基链),夹在一种镁原子,也与氯化离子相协调;这种化合物一般没有色,不光黄色液体或固体,视其状态和纯度而定;作为阻燃剂,它具有高度反应性,特别是水和蛋白溶剂,导致碳氢化合物和氢化镁的形成;它被用于各种反应,包括碳化合物的核毒添加物,从而在随后的水解后形成酒精;1-二苯基氯化物的再活性使它成为合成有机化学中的宝贵工具,从而可以构建复杂的分子结构;然而,由于它的再活性,它必须在水中处理,并具有适当的安全措施,以防止危险反应.

结构式图片

欧盟法规

ECHA物质C&L通报

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CAS号543-59-9 氯代正戊烷 | CAS号4292-92-6 戊基环己烷 | CAS号20172-33-2 N-(4-methylphen... | CAS号19841-72-6 2,2-二甲基-3-辛醇 | CAS号693-54-9 2-癸酮 | CAS号73013-39-5 氯甲基二甲基苯基硅烷 | CAS号589-98-0 辛醇 | CAS号107-72-2 戊基三氯硅烷 | CAS号10340-23-5 顺-3-壬烯-1-醇 | CAS号123-05-7 2-乙基已基醛 | CAS号1120-21-4 正十一烷

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    专利信息


    专利号:US-4922049-A
    优先权日:1989-01-13
    标 题:Synthesis of cis-olefins
    发明人:BYERS JIM D
    权利人:PHILLIPS PETROLEUM CO
    摘要:A process for the synthesis of cis-olefins from cis-olefinic alcohols consisting essentially of the following steps: n (a) reacting a cis-olefinic alcohol with a source of an alkali metal ion selected from the group consisting of lithium and sodium ions to form a first reaction product, n (b) then contacting said thus formed first reaction product with a sulfonyl halide compound to form a second reaction product, n (c) then containing said thus formed second reaction product with an alkyl magnesium compound and a cuprous salt to form a third reaction product comprising a cis-olefin wherein said steps are carried out in a suitable organic solvent.

    专利号:WO-2023237381-A1
    优先权日:2022-06-09
    标题:Process for the synthesis of polyethylenes or copolymers of ethylene and 1,3-diene having a terminal ketone function
    发明人:BOISSON CHRISTOPHE; D'AGOSTO FRANCK; DESGRANGES ARIANE; NGO ROBERT; JEAN-BAPTISTE-DIT-DOMINIQUE FRANÇOIS
    权利人:MICHELIN & CIE; CENTRE NAT RECH SCIENT; ECOLE SUPERIEURE DE CHIMIE PHYSIQUE ELECTRONIQUE LYON; UNIV CLAUDE BERNARD LYON
    摘要:The invention relates to a method for preparing a polyethylene having a terminal ketone function or a copolymer of ethylene and a 1,3-diene and optionally a vinyl aromatic compound which contains more than 50 mol% of ethylene and has a terminal ketone function; said method comprises a polymerization reaction of the monomers in the presence of a borohydrido-neodymocene complex and an organo-magnesium compound, followed by a coupling reaction with a compound having a nitrile function, and then a hydrolysis reaction.

    专利号:US-6175009-B1
    优先权日:1999-11-18
    标题:Process for the preparation of quinazolinones
    发明人:CONFALONE PASQUALE NICHOLAS; MAGNUS NICHOLAS ANDREW; STORACE LOUIS
    权利人:DU PONT PHARM CO
    摘要:The present invention relates generally to an asymmetric synthesis of 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolinones, and intermediates thereof. The target compounds are useful for the treatment of human immunodeficiency virus (HIV) as an inhibitor of reverse transcriptase.

    专利号:WO-0029391-A1
    优先权日:1998-11-19
    标题 :Process for the preparation of quinazolinones
    发明人:CONFALONE PASQUALE NICHOLAS; MAGNUS NICHOLAS ANDREW; STORACE LOUIS
    权利人:DU PONT PHARM CO
    摘要:The present invention relates generally to an asymmetric synthesis of 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolinones, and intermediates thereof. The target compounds are useful for the treatment of human immunodeficiency virus (HIV) as an inhibitor of reverse transcriptase.

    专利号:US-4740627-A
    优先权日:1987-05-21
    标题:Synthesis of E,Z-11-tetradecen-1-al
    发明人:BYERS JIM D; DRAKE CHARLES A
    权利人:PHILLIPS PETROLEUM CO
    摘要:The present invention pertains to a process for making a E,Z-11-tetradecen-1-al containing from 80 to 83 mole percent of the E isomer and from 17 to 20 mole percent of the Z isomer which exhibits pheromone-like activity for the spruce bud worm (choristoneura fumiferana).

    专利号:US-9243004-B2
    优先权日:2011-07-22
    标题 :Synthesis of boronic esters and boronic acids using grignard reagents
    发明人:CLARY JACOB W; SINGARAM BAKTHAN
    权利人:CLARY JACOB W; SINGARAM BAKTHAN; UNIV CALIFORNIA
    摘要:Boronic esters and boronic acids are synthesized at ambient temperature in an ethereal solvent by the reaction of Grignard reagents with a boron-containing substrate. The boron-containing substrate may be a boronic ester such as pinacolborane, neopentylglycolborane, or a dialkylaminoborane compound such as diisopropylaminoborane. The Grignard reagents may be pre-formed or generated from an alkyl, alkenyl, aryl, arylalkyl, heteroaryl, vinyl, or allyl halide compound and Mg 0 . When the boron-containing substrate is a boronic ester, the reactions generally proceed at room temperature without added base in about 1 to 3 hours to form a boronic ester compound. When the boron-containing substrate is a dialkylaminoborane compound, the reactions generally proceed to completion at 0° C. in about 1 hour to form a boronic acid compound.
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    合成参考文献


    摘要:Ohno, H.; Tomioka, K., Science of Synthesis, (2008) 44, 94.
    摘要:Kantchev, E. A. B.; Organ, M. G., Science of Synthesis, (2009) 48, 38.
    摘要:Cherkinsky, M.; Levinger, S., Science of Synthesis, (2010) 47, 482.
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