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CAS号85231-79-4 diethyl N-exo-n... | CAS号498-66-8 降冰片烯 | CAS号934-29-2 (2S)-降莰烷-2-羧酸专利信息
专利号:WO-2024035626-A1
优先权日:2022-08-11
标 题:Halophthalimide compounds and methods of use against tbi, inflammatory disorder, autoimmune disorder, neurodegenerative disease or viral infection
发明人:GREIG NIGEL; LUO WEIMING; TWEEDIE DAVID; SCERBA MICHAEL; LECCA DANIELA; HSUEH SHIH CHANG; KIM DONG SEOK
权利人:US HEALTH; AEVISBIO INC
摘要:Halophthalimides are disclosed. The halophthalimides may inhibit TNF-α activity, TNF-α synthesis, inflammation, inducible nitric oxide synthase, SARS-CoV-2 virus, or any combination thereof. The halophthalimides may be administered to a subject with a traumatic brain injury, an inflammatory disorder, an autoimmune disorder, a neurodegenerative disease, a viral infection, or any combination thereof. The disclosed halophthalimides have a structure according to Formula (I), or a stereoisomer or pharmaceutically acceptable salt, solvate, or hydrate thereof,
专利号:US-4853389-A
优先权日:1987-07-24
标 题:Diuretic and antihypertensive substituted-5-pyrimidinesulfonylureas
发明人:DOLAK TERENCE M; LEE SUNG J; BULLINGTON JAMES L
权利人:AMERICAN HOME PROD
摘要:This invention relates to substituted 5-pyrimidinesulfonamides, pharmaceutically acceptable salts thereof and to processes for synthesis thereof. Other aspects of the invention concern pharmaceutical compositions containing an instant compound as active ingredient and methods of treatment where there is an indicated need for an antihypertensive and/or diuretic agent.
专利号:US-4914203-A
优先权日:1987-07-24
标题:5 step process for preparing certain 2,4-diamino-5-pyrimidine-sulfonyl ureas
发明人:DOLAK TERENCE M; LEE SUNG J; BULLINGTON JAMES L
权利人:AMERICAN HOME PROD
摘要:This invention relates to substituted 5-pyrimidinesulfonamides, pharmaceutically acceptable salts thereof and to processes for synthesis thereof. Other aspects of the invention concern pharmaceutical compositions containing an instant compound as active ingredient and methods of treatment where there is an indicated need for an antihypertensive and/or diuretic agent.