CAS: 164513-38-6; 5-Bromo-2-Hydroxy-4-Methylpyridine

相似化合物

18368-59-7 1227562-37-9 164513-39-7

上下游产品

2-amino-5-bromo-4-methylpyridine 2-hydroksy-4-methyl-pyridine 5-bromo-2-methoxy-4-methylpyridine 3-bromo-4-bromomethyl-6-methoxypyridine 5-bromo-2-(difluoromethoxy)-4-methylpyridine 5-bromo-2-chloro-4-methylpyridine

2-氨基-5-溴-4-甲基吡啶置于sodium Nitrite体系中,用 硫酸,水 用作溶剂,以31%的收率获得5-溴-2-羟基-4-甲基吡啶
参考文献:(Hetero)-Aryl Ketones Derivatives With Antibacterial Properties
标题:(Hetero)-Aryl Ketones Derivatives With Antibacterial Properties
摘要:通过莫尼酸衍生的构象受限芳基和杂环酮具有有用的抗菌性能.

专利信息

专利号:WO-2024159285-A1
优先权日:2023-01-30
标题 :Nav1.7- and/or nav1.8-inhibiting aryl pyridine compounds, processes for the preparation thereof, compositions, uses, methods for treatment using same, and kits
发明人：BARREIRO GABRIELA; SANT’ANA DANILO PEREIRA DE; MONTEIRO JÚLIA LAMMOGLIA; GAMBA LUIS EDUARDO REINA; LIMA LÃ?DIA MOREIRA; FRAGA CARLOS ALBERTO MANSSOUR; BARREIRO ELIEZER JESUS DE LACERDA
权利人:EUROFARMA LABORATORIOS S A; UNIV FEDERAL DO RIO DE JANEIRO – UFRJ
摘要:The present invention relates to Nav1.7- and/or Nav1.8-inhibiting aryl pyridine compounds. More specifically, the present invention relates to aryl pyridines comprising formula (I): (I), in which the substituents R1 to R10 are selected independently of the groups defined in the description, as well as to processes for preparing same, compositions comprising at least one of these compounds, uses, treatment methods for treating or preventing pain-related pathologies, and kits. The present invention pertains to the fields of medicinal chemistry and organic synthesis, as well as to the treatment of pain-related diseases.

专利号:CN-118754847-A
优先权日:2024-06-07
标 题 :Convenient synthesis method of N-alkyl substituted pyridone compound

专利号:CN-118724798-A
优先权日:2024-07-18
标题 :Efficient synthesis method of (Z) -N-alkenyl-2-pyridone compound