CAS: 10320-42-0; 2-Chloro-5-Nitropyrimidine

相似化合物

56621-90-0 1210824-80-8 49845-33-2

上下游产品

CAS号540-80-7 亚硝酸叔丁酯 | CAS号3073-77-6 2-氨基-5-硝基嘧啶 | CAS号7447-39-4 无水氯化铜 | CAS号3264-10-6 2-羟基-5-硝基嘧啶 | CAS号56621-90-0 5-氨基-2-氯嘧啶 | CAS号14001-70-8 2-(甲硫基)-5-硝基嘧啶 | CAS号14001-69-5 2-甲氧基-5-硝基嘧啶 | CAS号1450-76-6 2-羟基-5-硝基苯乙酮 | CAS号88626-94-2 3-(5-nitropyrim... | CAS号65735-66-2 4-(5-硝基嘧啶-2-基)吗啉 | CAS号943749-60-8 2-(4-甲基-1-哌嗪)-5-硝基嘧啶

2-羟基-5-硝基嘧啶置于三氯氧磷体系中,化学反应 0.5H,以97%的收率获得2-氯-5-硝基嘧啶
参考文献:Hurst,Derek T.,Heterocycles,1984,Vol. 22,# 1,P. 79-84
标题:Hurst,Derek T.,Heterocycles,1984,Vol. 22,# 1,P. 79-84

专利信息

专利号:US-11053243-B2
优先权日:2009-03-27
标 题:Inhibitors of hepatitis C virus replication
发明人：COBURN CRAIG A; LUDMERER STEVEN W; LIU KUN; WU HAO; SOIL RICHARD; ZHONG BIN; ZHU JIAN
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-9090661-B2
优先权日:2009-03-27
标 题:Inhibitors of hepatitis C virus replication
发明人：COBURN CRAIG A; MCCAULEY JOHN A; LUDMERER STEVEN W; LIU KUN; VACCA JOSEPH P; WU HAO; HU BIN; SOLL RICHARD; SUN FEI; WANG XINGHAI; YAN MAN; ZHANG CHENGREN; ZHENG MINGWEI; ZHONG BIN; ZHU JIAN
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-9782406-B2
优先权日:2011-10-25
标 题 :Kinase inhibitor and method for treatment of related diseases
发明人：PAN ZHENGYING; LI XITAO
权利人:UNIV PEKING SHENZHEN GRADUATE SCHOOL; BEIJING RECIPROCAPHARMACEUTICALS CO LTD; BEIJING RECIPROCAPHARMACEUTICALS CO LTD
摘要:Disclosed is a compound of (aminophenylamino) pyrimidyl benzamides and a synthesis method thereof. The compound has Btk-inhibition activity and can be used to treat autoimmune diseases, heteroimmune diseases, cancers or thromboembolic diseases.

专利号:US-9150522-B2
优先权日:2011-10-25
标 题:Kinase inhibitor and method for treatment of related diseases
发明人：PAN ZHENGYING; LI XITAO
权利人:UNIV PEKING SHENZHEN GRAD SCHO; BEIJING RECIPROCAPHARMACEUTICALS CO LTD
摘要:Disclosed is a compound of (aminophenylamino) pyrimidyl benzamides and a synthesis method thereof. The compound has Btk-inhibition activity and can be used to treat autoimmune diseases, heteroimmune diseases, cancers or thromboembolic diseases.

专利号:CN-101219997-B
优先权日:2008-01-02
标 题 :Synthesis of 2-chlorine-5- amido pyrimidine

专利号:CN-101219997-A
优先权日:2008-01-02
标题 :Synthesis of 2-chlorine-5- amido pyrimidine