2',6'-二甲基-L-酪氨酸置于盐酸体系中,用 水 用作溶剂,化学反应生成(S)-2',6'-二甲基酪氨酸盐酸盐
参考文献:A Highly Efficient Stereocontrolled Synthesis Of (S)-2',6'-Dimethyltyrosine [(S)-Dmt]
标题:A Highly Efficient Stereocontrolled Synthesis Of (S)-2',6'-Dimethyltyrosine [(S)-Dmt]
摘要:A New,Practical And Very Convenient Stereocontrolled Synthesis Of (S)-2',6'-Dimethyltyrosine [(S)-Dmt] 4 Was Accomplished In A Good Yield,Starting From The Chiral Synthon 1.4-N,N-[(S)-Phenylethyl]-Piperazine-2,5-Dione 1. The Procedure,Which Is An Extension Of Our Original Strategy And occurs With A High Level Of Stereoselectivity (>98%),Is Simple And Inexpensive Allowing Lis To Prepare The Unnatural Alpha-Aminoacid (S)-Dmt Also On A Multi-Gram Scale. (C) 2009 Elsevief Ltd. All Rights Reserved.
Doi:10.1016/j.Tetasy.2009.06.004