CAS: 152751-57-0; 2-Propen-1-Amine-2-(Chloromethyl)Oxirane (1:1)

盐酸,丙烯胺,,乙酸乙酯置于bis[2-(4,5-Dihydro-1H-Imidazol-3-Ium-2-yl)Propan-2-Yl]Diazene;Dichloride 水,Water Isopropylalcohol,异丙醇体系中,用 水 用作溶剂,化学反应 23.5H,以to Give 6.68 G Of Sevelamer Hydrochloride的收率获得盐酸司维拉姆
参考文献:Process For The Preparation Of Cross-Linked Polyallylamines Or Pharmaceutically Acceptable Salts Thereof
标题:Process For The Preparation Of Cross-Linked Polyallylamines Or Pharmaceutically Acceptable Salts Thereof
摘要:本发明涉及一种制备交联聚丙烯胺或其药学上可接受的盐的过程.本发明还涉及一种制备sevelamer或其药学上可接受的盐的过程,优选氯化物盐或碳酸盐,用于治疗高磷血症,具有非常好的流动性,低孔隙度和/或7至9之间的膨胀指数.

专利信息

专利号:WO-2024239219-A1
优先权日:2023-05-23
标题 :Synthesis method for layered bimetal-based nano lanthanum material that synchronously locks phosphorus, removes algae and reduces turbidity, and use thereof
发明人：ZHANG YANYANG; SHEN CHAOYANG; KONG BO; JIA YULU; PAN BINGCAI; ZHANG WEIMING
权利人:NANJING UNIVERSITY
摘要:The present invention belongs to the field of environmental functional materials. Disclosed are a synthesis method for a layered bimetal-based nano lanthanum material that synchronously locks phosphorus, removes algae and reduces turbidity, and the use thereof. In the present invention, the preparation method comprises: synthesizing an LDH by means of a single-drop co-precipitation method, filtering out the obtained product, washing same with distilled water and drying same, then adding the product to an alcohol solution of a lanthanum salt at a certain concentration, stirring same for reaction, in situ precipitating lanthanum ions by adjusting the pH value of the solution, filtering out the reaction precipitate, washing same with an alcohol, and drying same to obtain an LDH-based nano lanthanum material. Lanthanum of the LDH-based nano lanthanum material prepared in the present invention is distributed between LDH layers and on the surfaces of the LDH in a weak crystalline state, and when the material is added to a water body, some of lanthanum can be hydrolyzed to generate a large number of positive charges and can be complexed with hydroxyl groups on the surface of the LDH to form a chain structure of [La(OH)m(H2O)n](3-m)+, which exerts the functions of adsorption and charge neutrality, precipitate net capturing, etc., to rapidly reduce the turbidity and settle algae suspended solids in the water body; and La2(CO3)3 and La(OH)3 growing between the layers can be further specifically combined with phosphate radicals in the water body to form stable LaPO4 crystals, thereby guaranteeing the stable phosphorus removal capacity thereof.

专利号:CN-102675510-A
优先权日:2012-05-28
标 题 :Synthesis of Sevelamer

专利号:CN-102675510-B
优先权日:2012-05-28
标 题:Synthesis process of Sevelamer