CAS: 7154-75-8; 4-Methyl-1-Pentyne

化学文摘社编号7154-75-8的化合物为3-甲基-1-苯,其分子式为C6H10.这种物质在室内温度上是一种无色液体,以其独特的气味而著称;Mephenty在水中是溶解的,但在有机溶剂中是溶解的,因此在各种化学应用中有用;它易燃,应当谨慎处理,因为吸入或摄入后会给健康带来危险;该化合物经常用于有机合成,并在其他化学品的生产中作为中间体;其活性是丙烷的典型,允许在合成有机化学中产生各种额外的反应,在合成有机化学中可以加以利用;在与该化合物打交道时,应当注意适当的安全措施,因为其易燃性和潜在健康危害.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号80687-80-5 1,1-dichloro-3-... | CAS号246023-18-7 1,1-dichloro-4-... | CAS号263904-17-2 1,1,1-trichloro... | CAS号691-37-2 4-甲基-1-戊烯 | CAS号6111-18-8 1,1,1-trichloro... | CAS号246023-15-4 1,1-dichloro-4-... | CAS号90701-59-0 1,1-dibromo-4-m... | CAS号872281-93-1 1,2,2-tribromo-... | CAS号10306-94-2 2-Methyl-4-°Ctyne | CAS号66225-20-5 3-Heptene, 6-me... | CAS号3404-80-6 2-methyl-4-meth... | CAS号65236-44-4 5-methyl-1-phen... | CAS号825622-15-9 6-methylhept-3-... | CAS号85110-24-3 6-(4-methylpent... | CAS号53566-37-3 5-甲基-2-己烯

合成工艺路线路线简述

    4-甲基-1-戊烯置于氢氧化钾,氯仿,溴体系中,化学反应生成 4-甲基-1-戊炔
    参考文献:Van Risseghem,Bulletin Des Societes Chimiques Belges,1933,Vol. 42,P. 235
    标题:Van Risseghem,Bulletin Des Societes Chimiques Belges,1933,Vol. 42,P. 235

    海关参考信息

    专利信息


    专利号:US-2025026768-A1
    优先权日:2023-06-30
    标题:Method for the synthesis of axially chiral organoboron compounds
    发明人:PING YIFAN; CHE CHI-MING
    权利人:LABORATORY FOR SYNTHETIC CHEMISTRY AND CHEMICAL BIOLOGY LTD
    摘要:A highly efficient and atroposelective Rh-catalyzed [2+2+2] cycloaddition for the synthesis of axially chiral aryboron compounds is developed. The reactions of diynes and alkynylborons smoothly occur in an atom-economical manner, affording a variety of C—B atropisomers in excellent yields and enantioselectivities. The protocol features mild conditions, broad substrate scope, and good functional tolerance. The obtained C—B atropisomers show powerful synthetic applications in terms of producing novel chiral phosphine ligands.

    专利号:US-7632975-B2
    优先权日:2004-12-22
    标 题:Process for the synthesis of arylfluorenes and analogs thereof
    发明人:HEIDENHAIN SOPHIE
    权利人:CDT OXFORD LTD
    摘要:A process is provided for the synthesis of a compound of formula (I): n nwherein:n M=0 or 1; N and p are 0 or 1 to 4; X is a single bond, O, S or NH; And R 1 -R 4 are as defined in claim 1.

    专利号:US-10570114-B2
    优先权日:2016-05-19
    标题:Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct suzuki coupling
    发明人:FISK JASON S; LI XIAOYONG; Muehlfeld Mark; BAUMAN ROBERT S; OPPENHEIMER JOSSIAN; TU SIYU; NITZ MARK A; CHAKRABARTI REETAM; FEIST SHAWN D; RINGER JAMES W; LENG RONALD B
    权利人:DOW AGROSCIENCES LLC
    摘要:Improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates and arylalkyl and alkyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates, are described herein. The improved methods include a direct Suzuki coupling step, which eliminates the protection/de-protection steps in the current chemical process, and therefore eliminates or reduces various raw materials, equipment and cycle time as well as modification of other process conditions including use of crude AP, use of ABA-diMe, and varying pH, catalyst concentration, solvent composition, and/or workup procedures. This includes synthesis of 2-aryl-6-aminopyrimidine-4-carboxylates.

    专利号:US-2013184465-A1
    优先权日:2010-09-30
    标 题:Process for the synthesis of thio-triazolo-group containing compounds
    发明人:DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL
    权利人:DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL; BASF SE
    摘要:The present invention relates to a process using specific magnesium reagents for providing thio-triazolo group-containing compounds and for the synthesis of precursors therefor. The invention furthermore relates to intermediates and to their preparation.

    专利号:US-2025188104-A1
    优先权日:2023-12-06
    标题 :Sequential One-Pot Synthesis of Alkylidyne and Alkylidene Catalysts
    发明人:VEIGE ADAM S; BOECK PARK
    权利人:THE UNIV OF FLORIDA RESEARCH FOUNDATION INC
    摘要:A method of preparing a tetraanionic pincer ligand supported metallacycloalkylene complex in one pot, the method including admixing at low temperature a solution of [ t BuOCO]H 3 and a solution of ( t BuO) 3 W≡CC(CH 3 ) 3 in a second solvent to form a first reaction mixture, warming the first reaction mixture, removing at least a portion of solvent from the first reaction mixture to provide a second reaction mixture, admixing the second reaction mixture and a solvent to form a third reaction mixture, admixing at low temperature the third reaction mixture and a base to form a fourth reaction mixture, warming the fourth reaction mixture to form a fifth reaction mixture; removing at least a portion of the third solvent from the fifth reaction mixture to provide a sixth reaction mixture; washing the sixth reaction mixture with a fifth solvent and removing at least a portion of the fifth solvent to form a seventh reaction mixture; admixing the seventh reaction mixture with a sixth solvent to provide an eighth reaction mixture; cooling the eighth reaction mixture and admixing the eighth reaction mixture with methyl trifluoromethansulfonate to form a ninth reaction mixture; warming the ninth reaction mixture, and admixing a substituted alkyne with the ninth reaction mixture to form the tetraanionic pincer ligand supported metallacycloalkylene complex (1).

    专利号:US-2020354404-A1
    优先权日:2019-05-09
    标 题 :Peptidomimetic agents, synthesis and uses thereof
    发明人:AL-ABED YOUSEF
    权利人:FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
    摘要:Compounds for use in synthesis of peptidomimetic agents; synthesis of peptidomimetic agents; peptidomimetic diagnostic and therapeutic agents; and uses of the compounds and peptidomimetic agents in drug discovery, diagnosis, prevention and treatment of diseases are described.
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    合成参考文献


    摘要:Razin, V. V., Science of Synthesis, (2010) 47, 887.
    摘要:Durand, A.; Hemeon, I.; Singer, R. D., Science of Synthesis Knowledge Updates, (2013) 2, 144.
    摘要:Trofimova, A.; Sirvinskas, M.; Yudin, A. K., Science of Synthesis Knowledge Updates, (2021) 2, 59.
    摘要:Tian, T.; Li, Z., Science of Synthesis Knowledge Updates, (2020) 2, 376.
    摘要:Nakao, Y., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 1, 332.
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