CAS: 143426-49-7; (4-Pyrazol-1-Yl-Phenyl)Methanol

相似化合物

16209-00-0 99662-34-7 400750-29-0

上下游产品

CAS号143426-47-5 4-(1-吡唑基)苯甲酸甲酯 | CAS号451-46-7 4-氟苯甲酸乙酯 | CAS号99662-34-7 4-(1H-吡唑-1-基)苯甲醛 | CAS号65476-24-6 [4-(1H-吡唑-1-基)苯基]乙酸

4-(1-吡唑)苯甲酸甲酯置于lithium Aluminium Tetrahydride体系中,用 四氢呋喃 用作溶剂,化学反应 2.0H,以91%的收率获得1-(4-羟甲基苯基)吡唑
参考文献: Pyrrolidine Glycosidase Inhibitors[fr] Inhibiteurs De Pyrrolidine Glycosidase
标题: Pyrrolidine Glycosidase Inhibitors[fr] Inhibiteurs De Pyrrolidine Glycosidase
摘要:式(i)中a,W,R3B,Z和p的含义如权利要求所述,可用于治疗tau病和阿尔茨海默病.

专利信息

专利号:US-9708278-B2
优先权日:2013-11-27
标 题 :Substituted 4-benzyl-3,4-dihydro-2H-benzo[B][1,4]oxazine-2-carboxamide analogs as positive allosteric modulators of muscarinic acetycholine receptor M1
发明人：LINDSLEY CRAIG W; CONN P JEFFREY; STAUFFER SHAUN R; PANARESE JOSEPH D
权利人:UNIV VANDERBILT
摘要:In one aspect, the invention relates to N-substituted 3,4-dihydro-benzo[£][1,4]oxazine-2-carboxamide analogs, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the muscarinic acetylcholine receptor M 1 (mAChR M 1 ); synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

专利号:US-7825149-B2
优先权日:2006-01-19
标 题 :Substituted imidazoles
发明人：CHUBB NATHAN ANTHONY LOGAN; COX MARK ROGER; DAUVERGNE JEROME SEBASTIEN; EWIN RICHARD ANDREW; LAURET CHRISTELLE
权利人:PFIZER LTD
摘要:This invention relates to a range of alpha substituted 2-benzyl substituted imidazole compounds and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes for their synthesis and their use as parasiticides.