CAS: 723284-81-9; (R)-3-Amino-3-(3-Fluorophenyl)Propanoic Acid

该化合物是一种非天然的氨基酸衍生物,具有氟化芳香侧链,其结构形态将β-氨基酸框架与3-氟苯基组结合,在药用化学和peptide研究中具有价值.氟代用可增强代谢稳定性和影响约束性互动,而(R)配置为定向应用提供了立体化学特性.该化合物是生物活性分子合成的多用途中间体,特别是CNS定位药物和酶抑制剂,其高纯度和定义明确的立体化学确保研究环境中的再生.氟苯基分子也为机械学研究中的光谱跟踪提供便利.

英文名称(R)-3-Amino-3-(3-Fluorophenyl)Propanoic Acid
中文名称(R)-3-氨基-3-(3-氟苯基)丙酸
IUPAC名称(R)-3-amino-3-(3-fluorophenyl)propanoic acid
其它别名(R)-3-氨基-3-(3-氟苯基)-丙酸; H-D-B-Phe(3-F)-Oh
CAS编号723284-81-9
MFCD编号:MFCD04113656
EINECS号:111-867-0
分子式:C9H10FNO2
分子量:183.18
产品CID: 1708892
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
InChIKey: GZNJUJNKZBHINS-MRVPVSSYSA-N
InChI=1S/C9H10FNO2/c10-7-3-1-2-6(4-7)8(11)5-9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m1/s1…
计算化学: 氢键受体数2.0氢键供体数2可旋转键数3

MSDS等安全信息

GHS象形图
GHS符号GHS07;
注释: Exclamation mark
危险类别皮肤腐蚀/刺激类别2
严重眼刺激类别2
警示词Warning(警告)
危险描述H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
防范说明P210-P233-P240-P241-P242-P243-P260-P261-P264-P270-P271-P273-P280-P301+P330+P331-P304+P340-P330-P363-P370+P378-P391-P405-P501
危险品标志Xi
安全声明H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body

欧盟法规

C&L通报

上下游产品

malonic acid 3-Fluorobenzaldehyde L-3-fluorophenylalanine 3-fluorophenylalanine 3-(3-Fluoro-phenyl)-3-(2,2,2-trifluoro-acetylamino)-propionic acid ethyl (+/-)-3-amino-3-(3-fluorophenyl)propanoate hydr°Chloride

合成工艺路线路线简述

海关参考信息

2902600000-乙苯
2905121000-正丙醇
2912110000-甲醛
2912120000-乙醛
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-9574189-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries
发明人：FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SÃ˜REN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SÃ˜RENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLÃ˜K FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim BirkebÃ¦; PEDERSEN LENE; NÃ˜RREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRÃ˜DER; NEVE SÃ˜REN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK
权利人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SÃ˜REN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SÃ˜RENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLÃ˜K FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim BirkebÃ¦; PEDERSEN LENE; NÃ˜RREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRÃ˜DER; NEVE SÃ˜REN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK; NUEVOLUTION AS
摘要:Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

专利号:US-11702652-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries

专利号:US-2009264300-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries

专利号:US-2020216836-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries

专利号:EP-1957644-B1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries

专利号:US-2019330618-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries