CAS: 112-10-7; Isopropyl Stearate

该化合物是一种来自异丙醇和石酸的酯,其特点是化学配方C21H42O2.它看起来是一种无色的黄色液体,其色味为浅色的黄色,有轻脂肪味;这种化合物以其发酵特性闻名,使它在化妆品和个人护理配方中成为常见成分,用来增强皮肤感觉和提供水分;在制作润滑剂时也使用异丙基锡酸,并在各种工业应用中用作溶剂;它具有相对较低的毒性特征,有助于其消费品的安全;此外,在正常条件下,它表现出良好的稳定性,尽管它应该储存在远离强氧化剂和极端温度的地方;它的溶性特征允许它在油中溶解,而水中溶解性较少,而脂肪酸酯通常使用这种溶液.

结构式图片

相似化合物

142-91-6 110-27-0 10233-13-3

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号111-61-5 硬脂酸乙酯 | CAS号67-63-0 异丙醇 | CAS号4130-54-5 硬脂酰肼 | CAS号57-11-4 硬脂酸 | CAS号112-61-8 硬脂酸甲酯 | CAS号187737-37-7 propene | CAS号3634-92-2 硬脂酸丙酯 | CAS号123-95-5 硬脂酸丁酯

合成工艺路线路线简述

    硬脂酸丙酯置于四氯化硅体系中,化学反应 19.0H,反应生成硬脂酸异丙酯
    参考文献:Silica Chloride: A Versatile Heterogeneous Catalyst For Esterification And Transesterification
    标题:Silica Chloride: A Versatile Heterogeneous Catalyst For Esterification And Transesterification
    摘要:已发现硅氯化物是一种高效的催化剂,适用于羧酸(脂肪族,芳香族和共轭)与醇(伯醇,仲醇和叔醇)的酯化反应,同时也适用于酯类的转酯化反应(通过醇解和酸解两种途径).
    Doi:10.1055/s-2003-42406

    海关参考信息

    专利信息


    专利号:US-7598291-B2
    优先权日:2004-09-02
    标题 :Methods and compositions for enhancing collagen and proteoglycan synthesis in the skin
    发明人:NIMNI MARCEL; HAN BO
    权利人:NIMNI MARCEL; HAN BO
    摘要:A composition for application to the skin can stimulate the in vivo synthesis of collagen and proteoglycans and improve the appearance of the skin, increasing its elasticity and fullness. In general, a composition according to the present invention comprises: (1) an antioxidant compound in a quantity sufficient to enhance collagen synthesis in the skin; (2) an organic penetrant in which the antioxidant compound is soluble in a sufficient quantity that a concentration of the antioxidant compound sufficient to enhance collagen synthesis can be applied topically and penetrate the skin; (3) a mixture of essential amino acids; (4) a supplemental source of sulfur; and (5) a topical pharmaceutically acceptable carrier. The antioxidant compound can be lipoic acid, a lipoic acid analogue or derivative, a bioflavonoid, a constituent of ginkgo, or an isoflavone. The organic penetrant is preferably benzyl alcohol. Other ingredients, such as esters of tocopherol and ascorbic acid, can be included.

    专利号:US-2010160244-A1
    优先权日:2004-09-02
    标 题 :Methods and compositions for enhancing collagen, proteoglycan, and glutathione synthesis in the skin
    发明人:NIMNI MARCEL; HAN BO
    权利人:NIMNI MARCEL; HAN BO
    摘要:A composition for application to the skin can stimulate the in vivo synthesis of collagen and proteoglycans and improve the appearance of the skin, increasing its elasticity and fullness. In general, a composition according to the present invention comprises: (1) an antioxidant compound in a quantity sufficient to enhance collagen synthesis in the skin; (2) an organic penetrant in which the antioxidant compound is soluble in a sufficient quantity that a concentration of the antioxidant compound sufficient to enhance collagen synthesis can be applied topically and penetrate the skin; (3) a mixture of essential amino acids or hydrolyzed whey protein; (4) a supplemental source of sulfur; and (5) a topical pharmaceutically acceptable carrier. The antioxidant compound can be lipoic acid or a lipoic acid analogue or derivative. The organic penetrant is preferably benzyl alcohol. Other ingredients, such as esters of tocopherol and ascorbic acid, can be included.

    专利号:US-7722904-B2
    优先权日:2007-11-01
    标 题 :Compositions and methods for stimulating synthesis of pro-collagen or collagen and hyaluronic acid
    发明人:SCHNEIDER LOUISE M; PUSATERI DONALD J; LA TOM Q
    权利人:ACCESS BUSINESS GROUP INT LLC
    摘要:A method for improving the appearance, texture and/or moisture of skin comprising administering a composition comprising Chia Seed oil, Opuntia ficus Indica extract, or both to stimulate collagen or hyaluronic acid synthesis, or decrease Interleukin-1b synthesis, in the skin.

    专利号:US-10799441-B2
    优先权日:2011-06-06
    标题:Skin treatments containing pyrroloquinoline quinone (PQQ) esters and methods of preparation and use thereof
    发明人:LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C
    权利人:LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C; PCR TECH HOLDINGS LC
    摘要:The present invention relates to cosmetic or dermatological compositions containing PQQ or its esters, methods of treating or promoting skin changes by topical application of these compositions, and methods of synthesis of PQQ esters. The PQQ ester-containing compositions of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the PQQ esters of the present invention have an antioxidant effect that is useful in treating a skin change.

    专利号:WO-2023197278-A1
    优先权日:2022-04-15
    标题 :Solvent-free synthesis method for sucrose ester having high monoester content
    发明人:XU SHENG; LIANG ZHENMING; Min Juping; SHAO LEI; XU HUAIYI
    权利人:GUANGZHOU CARDLO BIOCHEMICAL TECH CO LTD
    摘要:Disclosed is a solvent-free synthesis method for a sucrose ester having high monoester content. The method comprises the following steps: (1) mixing sucrose, a higher fatty acid ester, and a higher fatty acid salt, and preheating at 70-90°C to obtain a mixture; and (2) mixing the mixture and a catalyst, and reacting at 120-140°C to obtain the sucrose ester. According to the synthesis method involved in the present application, a solvent-free ester transesterification method is used, the sucrose, the higher fatty acid ester, the higher fatty acid salt, and the catalyst turn into a co-molten state in a certain ratio at a high temperature, and the sucrose ester is catalytically synthesized under reaction conditions facilitating kinetics. According to the synthesis method, the use of a solvent is avoided, the problem of toxicity is solved, a product can meet medical and edible standards, sucrose monoester content in the product is high, and the color of the prepared product is good; the synthesis method has simple steps, facilitates industrial production, and has important application value.

    专利号:US-2008108681-A1
    优先权日:2006-10-27
    标题:Use of allantoin as a pro-collagen synthesis agent in cosmetic compositions
    发明人:SCIMECA JOHN V; FAST DAVID J; ZIMMERMAN AMY C
    权利人:ACCESS BUSINESS GROUP INT LLC
    摘要:Compositions comprising allantoin and an acceptable carrier and methods of using such compositions to increase pro-collagen synthesis in skin are disclosed. Compositions of the present invention may be used to decrease the signs of skin aging such as wrinkles and fine lines. Compositions of the present invention may be topically administered, orally administered or parenterally, such as administration by injection. When topically administered, additive ingredients such as penetration enhancers, fragrances, and moisturizers and cosmetic adjuvants may be included in compositions of the present invention.
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    合成参考文献


    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
    摘要:International Journal of Toxicology 24(Suppl. 1):1-102, 2005
    摘要:International Journal of Toxicology 34(Suppl.2):5-69, 2015
    摘要:Journal of the American College of Toxicology 4(5):107-146, 1985
    参考文献:10.1007/s00105-021-04866-6
    摘要:Mayser P, Koch C. [Malassezia spp.: interactions with topically applied lipids-a review : Malassezia and topically applied lipids]. Hautarzt. 2021 Oct;72(10):860–7. doi: 10.1007/s00105-021-04866-6.
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