CAS: 6294-17-3; 1-Bromo-6-Chlorohexane

相似化合物

54512-75-3 2163-00-0 629-03-8

上下游产品

CAS号2009-83-8 6-氯-1-己醇 | CAS号4286-55-9 6-溴正己醇 | CAS号629-11-8 1,6-己二醇 | CAS号544-10-5 氯(代)正己烷 | CAS号821-41-0 5-己烯-1-醇 | CAS号928-89-2 6-氯-1-己烯 | CAS号3922-28-9 1,12-二氯十二烷 | CAS号111-27-3 正己醇 | CAS号144366-95-0 1-(6-chlorohexy... | CAS号181515-33-3 7-di(propan-2-y... | CAS号19220-36-1 °Ctadec-8-ynoic acid | CAS号119-61-9 二苯甲酮

6-氯-1-己醇置于copper(II) Bis(Trifluoromethanesulfonate) N,N'-二异丙基碳二亚胺,乙酰溴体系中,用 四氢呋喃 作为反应溶剂,化学反应 0.16H,以96%的收率获得产物1-溴-6-氯己烷
参考文献:A Novel Stereoselective One-Pot Conversion Of Alcohols Into Alkyl Halides Mediated By N,N'-Diisopropylcarbodiimide
标题:A Novel Stereoselective One-Pot Conversion Of Alcohols Into Alkyl Halides Mediated By N,N'-Diisopropylcarbodiimide
摘要:通过相应的 O-烷基异脲,醇类可在一锅程序中高产率地转化为相应的烷基卤化物;使用微波辐照时,反应时间非常短.
DOI:10.1039/b211424K

专利信息

专利号:US-3872168-A
优先权日:1972-10-02
标题:Synthesis of acids and amides
发明人：COLLMAN JAMES P; WINTER STANLEY R; KOMOTO ROBERT G
权利人:TRUSTEES OF THE LELAND STAMFOR
摘要:Synthesis of acids R1COOH and amides R1CONR2R3 wherein R1 is attached to the carbonyl group by an aliphatic carbon atom and R2 and R3 are hydrogen or organic groups of a primary or secondary amine, by forming an alkyl or acyl intermediate (R1Fe(CO) 4 or R1COFe(CO) 4) and treating the intermediate with a suitable cleaving agent and, in the case of amides, also with ammonia or an amine.

专利号:US-4026911-A
优先权日:1976-02-23
标 题:Process for the preparation of ketoalkynoic acids and use of the process in an improved synthesis of 2-(substituted)-cyclo-pentane-1,3,4-triones
发明人：REVERMAN LAWRENCE FRANCIS
权利人:MILES LAB
摘要:Reaction of a 2-methyl-2-(alkenyl)-1,3-dioxolane with an α,ω-dihalogenoalkane to obtain a 2-methyl-2-(ω-chloroalkynyl)-dioxolane, conversion of the latter to a corresponding nitrile, and hydrolysis of the nitrile to form a ketoalkynoic acid is a novel process for preparing the acid. n Use of the process in the synthesis of 2-(substituted)-cyclopentane-1,3,4-triones improves that synthesis.

专利号:WO-2025136842-A1
优先权日:2023-12-19
标题 :Process for preparing n-aminoalkylated tryptophan compounds
发明人：CO SARAH S; DALBY STEPHEN M; JOHNSON KEYWAN ALEXANDER; KLAPARS ARTIS; KUETHE JEFFREY T; PETERS BYRON KENNEDY; SIROTA ERIC; WRIGHT TIMOTHY JAMES; XIAO KAIJIONG
权利人:MERCK SHARP & DOHME LLC
摘要:The present invention relates to processes useful in the synthesis of aminohexyl compounds, such as a compound of Formula I or a salt, hydrate and/or solvate thereof, as well as methods for the preparing a compound of Formula I and intermediates used to make a compound of Formula I. The present invention presents a novel method for the selective alkylation of tryptophan analogues, eliminating the need for protecting groups and advancing the field of tryptophan analogue synthesis.

专利号:WO-2013082150-A1
优先权日:2011-11-30
标题:Small molecule inhibitors of nicotinamide phosphoribosyltransferase (nampt)
发明人：LEE JR MARK WAYNE; SEVRYUGINA YULIA
权利人:UNIV MISSOURI; LEE JR MARK WAYNE; SEVRYUGINA YULIA
摘要:The present invention relates to novel compounds, their use as anti-cancer agents and their synthesis. In particular, the compounds contain cluster boron moieties such as carborane or a borohydride and act as inhibitors for the enzyme Nampt. The biological properties of the inventive cluster boron compounds, in terms of biological inhibition and antiproliferative effect, are greater than other small molecule inhibitors of Nampt.

专利号:US-9382267-B2
优先权日:2011-11-30
标题 :Small molecule inhibitors of nicotinamide phosphoribosyltransferase (NAMPT)
发明人：LEE JR MARK WAYNE; SEVRYUGINA YULIA
权利人:UNIV MISSOURI
摘要:The present invention relates to novel compounds, their use as anti-cancer agents and their synthesis. In particular, the compounds contain cluster boron moieties such as carborane or a borohydride and act as inhibitors for the enzyme Nampt. The biological properties of the inventive cluster boron compounds, in terms of biological inhibition and antiproliferative effect, are greater than other small molecule inhibitors of Nampt.

专利号:DE-2707128-A1
优先权日:1976-02-23
标 题:PROCESS FOR THE PREPARATION OF KETOALKYNIC ACIDS AND APPLICATION OF THE PROCESS TO AN IMPROVED SYNTHESIS OF 2- (SUBSTITUTE) -CYCLOPENTANE-1,3,4-TRIONEN