CAS: 121-97-1; P-Methoxypropiophenone

相似化合物

5349-60-0 4160-51-4 37951-49-8

上下游产品

CAS号79-03-8 丙酰氯 | CAS号100-66-3 苯甲醚 | CAS号51410-44-7 1'-hydroxyestragole | CAS号77-78-1 硫酸二甲酯 | CAS号70-70-2 4-羟基苯丙酮; 对羟基苯丙酮 | CAS号107-06-2 1,2-二氯乙烷 | CAS号503-17-3 2-丁炔 | CAS号123-11-5 4-甲氧基苯甲醛; 对甲氧基苯... | CAS号5349-60-0 1-(4-甲氧苯基)-1-丙醇 | CAS号104-92-7 对溴苯甲醚 | CAS号7099-91-4 2-(4-甲氧基苯基)-2-氧代乙酸 | CAS号100-09-4 对甲氧基苯甲酸 | CAS号208529-38-8 3-(dimethylamin... | CAS号18272-82-7 1-methoxy-4-pen... | CAS号2760-31-8 N-(4-甲氧基苯基)丙酰胺 | CAS号25413-27-8 3-(4-甲氧基苯基)-丙酰胺 | CAS号250277-92-0 1-Propanone, 2-... | CAS号7773-34-4 alpha;,alpha;pr... | CAS号21086-33-9 2-溴-1-(4-甲氧苯基)丙酮 | CAS号645-56-7 4-丙基苯酚

茴香烯置于tetrafluoroboric Acid,氧气,Palladium Diacetate,对苯醌体系中,用 N,N-二甲基乙酰胺,水,乙腈 用作溶剂,化学反应 16.0H,以84%的收率获得对甲氧基苯丙酮
参考文献:实用和普通钯催化内烯烃合成酮
标题:实用和普通钯催化内烯烃合成酮
摘要:简单点!据报道,内烯烃可方便地通过钯催化氧化成酮.该转变在室温下发生,并显示出较宽的底物范围.描述了在种子油衍生物和生物活性天然产物(参见方案)的氧化中的应用,以及引人入胜的机械特性.
Doi:10.1002/anie.201209541

专利信息

专利号:US-9096519-B2
优先权日:2013-01-10
标 题 :Process for the synthesis of ketones from internal alkenes
发明人：MORANDI BILL; GRUBBS ROBERT H; WICKENS ZACHARY K; LERCH MICHAEL M
权利人:CALIFORNIA INST OF TECHN
摘要:The present invention is directed to methods for oxidizing internal olefins to ketones. In various embodiments, each method comprising contacting an organic substrate, having an initial internal olefin, with a mixture of (a) a biscationic palladium salt; and (b) an oxidizing agent; dissolved or dispersed in a solvent system to form a reaction mixture, said solvent system comprising at least one C 2-6 carbon nitrile and optionally at least one secondary alkyl amide, said method conducted under conditions sufficient to convert at least 50 mol % of the initial internal olefin to a ketone, said ketone positioned on a carbon of the initial internal olefin. The transformation occurs at room temperature and shows wide substrate scope. Applications to the oxidation of seed oil derivatives and a bioactive natural product are described.

专利号:US-9988368-B1
优先权日:2017-06-16
标题:Chiral synthesis method for producing cis-imidazoline compounds for pharmaceutical use
发明人：VON GELDERN THOMAS W; BACKES BRADLEY; CHEN BING
权利人:UNITY BIOTECHNOLOGY INC
摘要:This invention provides a method for enantioselective synthesis of cis-imidazolines and related structures through chiral resolution. A chiral acid is used to separate enantiomeric precursors of the cis-imidazolines from a racemic mixture by selective crystallization. Both enantiomers can be cyclized into the desired cis-imidazoline by complementary pathways. Compounds can be synthesized according to the invention with an enantiomeric excess as high as 99%. Cis-imidazolines such as Nutlin-3a prepared according to this invention may be used for treating cancer, killing senescent cells, or treating senescence-associated conditions.

专利号:US-6225463-B1
优先权日:1997-12-22
标 题 :Synthesis of new β-lactams
发明人：DE VOS DICK; BROWN STEPHEN; JORDAN ALLAN M; LAWRENCE NICHOLAS J; MCGOWN ALAN TH
权利人:PHARMACHEMIE BV; CANCER RES CAMPAIGN TECH
摘要:The object of the present invention is the development of new chiral auxiliaries for improved beta-lactam formation that control both the diastereoselectivity of beta-lactam formation and which can be removed without destruction of the sensitive azetidinone ring, providing valuable intermediates for coupling to the C-13 hydroxyl group of anti-tumor taxanes, such as paclitaxel. Further, the object of the present invention is enantiomerically pure (S)-(-)-1-(p-methoxy-phenyl)propyl-1-amine.

专利号:US-8981092-B2
优先权日:2008-09-19
标题 :Substituted 3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-ones as modulators of protein kinase activity
发明人：MIRIZZI DANILO; CERVI GIOVANNI; D ANELLO MATTEO; PAPEO GIANLUCA MARIANO ENRICO; FERGUSON RON; CASUSCELLI FRANCESCO
权利人:MIRIZZI DANILO; CERVI GIOVANNI; D ANELLO MATTEO; PAPEO GIANLUCA MARIANO ENRICO; FERGUSON RON; CASUSCELLI FRANCESCO; NERVIANO MEDICAL SCIENCES SRL
摘要:Compounds which are 4,7-disubstituted derivatives of 3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one compounds, n nor pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, viral infection, prevention of AIDS development in HIV-infected individuals, cell proliferative disorders, autoimmune and neurodegenerative disorders; also disclosed is a process under Solid Phase Synthesis conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.

专利号:US-2357985-A
优先权日:1940-07-30
标 题:Synthesis of hexoestrol
发明人：WALLIS EVERETT S; SEYMOUR BERNSTEIN
权利人:RESEARCH CORP

专利号:CN-106220495-A
优先权日:2016-08-01
标题 :Method for direct synthesis of unsaturated alkene-containing alpha-acyloxyketone derivatives by α-functionalization reaction of ketones