CAS: 40972-86-9; 2,3-Dimethoxybenzeneboronic Acid

上下游产品

CAS号91-16-7 1,2-二甲氧基苯 | CAS号121-43-7 硼酸三甲酯 | CAS号5424-43-1 2,3-二甲氧基溴苯 | CAS号5150-42-5 2,3-二甲氧基苯酚 | CAS号125-29-1 氢可酮 | CAS号125-28-0 二氢可待因 | CAS号19261-03-1 [1,1-二苯]-2,2,3,3-四醇 | CAS号1133-63-7 2,3-二羟基联苯 | CAS号6879-02-3 娃兒藤鹼

邻苯二甲醚置于正丁基锂,四甲基乙二胺,硼酸三甲酯,盐酸体系中,用 乙醚,正己烷 作为反应溶剂,化学反应 1.0H,以88%的收率获得产物2,3-二甲氧基苯硼酸
参考文献:Combined Directed Ortho Metalation/suzuki−miyaura Cross-Coupling Strategies. Regiospecific Synthesis Of Chlorodihydroxybiphenyls And Polychlorinated Biphenyls
标题:Combined Directed Ortho Metalation/suzuki−miyaura Cross-Coupling Strategies. Regiospecific Synthesis Of Chlorodihydroxybiphenyls And Polychlorinated Biphenyls
摘要:The Directed Ortho Metalation (Dom)/suzuki-Miyaura Cross-Coupling Strategy Is Applied For The Regiospecific Construction Of All Isomeric Monochloro And Selected Dichloro And Trichloro 2,3-Dihydroxybiphenyls (Dhbs). The Combined Methodology Highlights Iterative Dom Processes,Hindered Suzuki-Miyaura Couplings,And Advantages In Diversity In Approaches From Commercial Starting Materials Leading To Provision Of Chloro-Dhbs As Single Isomers In High Purity And On A Gram Scale. The Syntheis Of Several Pcbs Are Also Reported.
DOI:10.1021/jo062543I

专利信息

专利号:EP-1836163-B1
优先权日:2004-12-23
标题 :Pyrrolidine derivatives for the treatment of a disease depending on the activity of renin
发明人：BREITENSTEIN WERNER; COTTENS SYLVAIN; EHRHARDT CLAUS; JACOBY EDGAR; LORTHIOIS EDWIGE LILIANE JEANNE; MAIBAUM JUERGEN KLAUS; OSTERMANN NILS; SELLNER HOLGER; SIMIC OLIVER
权利人:NOVARTIS AG
摘要:Novel 3-mono-, 3,4-di- and 3,4,4,-tri-substituted pyrrolidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on inappropriate activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on inappropriate activity of renin; the use of a compound of that class in the treatment of a disease that depends on inappropriate activity of renin; pharmaceutical formulations comprising a said substituted pyrrolidine compound, and/or a method of treatment comprising administering a said substituted pyrrolidine compound, a method for the manufacture of said substituted pyrrolidine compounds, and novel intermediates and partial steps for their synthesis are described. The substituted pyrrolidine compounds are especially of the formula I wherein the substituents are as described in the specification.

专利号:CN-112839951-A
优先权日:2018-06-15
标 题:Synthesis of echinocandin antifungal agents

专利号:US-6599921-B2
优先权日:2001-02-22
标 题:Non-steroidal estrogen receptor ligands
发明人：SCHMIDT JONATHAN MARTIN; MERCURE JULIE; LOWELL JEFFRY LAWRENCE; KWIATKOWSKI STEFAN; PUPEK KRZYSZTOF; ZHU SHUGUANG; WHELAN JOHN; LAZAROWYCH NATALIE
权利人:NANODESIGN INC
摘要:Novel non-steroidal estrogen receptor ligands and methods of synthesis are disclosed. The novel molecules are intended for use in therapeutic preparations for the treatment of estrogen receptor related disease states. The compounds specified are tetra-cyclic derivatives and have been shown to be antiproliferative against human estrogen-dependent cancer cells and to have good binding affinity for the estrogen receptor.

专利号:US-6632835-B2
优先权日:2001-02-22
标题:Dibenzo[c]chromen-6-one derivatives as anti-cancer agents
发明人：SCHMIDT JONATHAN MARTIN; REDDEN PETER; MERCURE JULIE; ZHU SHUGUANG; WHELAN JOHN; LAZAROWYCH NATALIE
权利人:NANODESIGN INC
摘要:Molecules demonstrating anti-proliferative effects against epithelial cancer cell lines and endothelial cells and methods of synthesis are disclosed. The molecules are intended for use in therapeutic preparations for the treatment of cancer through either anti-angiogenesis or other anti-cancer mechanisms. The compounds specified are 6H-dibenzo[b,d]pyran-6-one derivatives and have been shown to be antiproliferative against human endothelial cells.