CAS: 911-77-3; N-(5-Guanidino-1-((4-Nitrophenyl)Amino)-1-Oxopentan-2-yl)Benzamide Hydrochloride

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CAS号125652-40-6 N2-苯甲酰基-精氨酸单盐酸盐 | CAS号100-01-6 对硝基苯胺 | CAS号6453-58-3 5-[[氨基(亚氨基)甲基]氨...

专利信息

专利号:US-10669306-B2
优先权日:2016-02-04
标题:Solid supports for use in solid-phase peptide synthesis, kits, and related methods
发明人：CHATTERJEE CHAMPAK; SHELTON PATRICK M; WELLER CAROLINE E
权利人:UNIV WASHINGTON
摘要:Solid supports for use in solid-phase peptide synthesis (SPPS) are provided. The solid supports may include a resin and a protected linker coupled to the resin. The linker may be an N-mercaptoethoxyglycine, an N-mercaptopropoxyglycine, an N-mercaptobutoxyglycine, and/or another suitable linker. Kits for use in SPPS are also provided. The kits may include a solid support, a solution including a thiol or a selenol, one or more pluralities of protected amino acids, and/or a wash buffer. Methods of SPPS are also provided. The methods may include providing a solid support including a resin coupled to a protected linker.

专利号:US-6713416-B2
优先权日:1999-07-30
标题:Molecularly-imprinted material made by template-directed synthesis
发明人：MARKOWITZ MICHAEL A; SCHOEN PAUL E; GABER BRUCE P; RATNA BANAHALLI R; KUST PAUL R; TURNER DAVID C; CLARK DOUGLAS S; DORDICK JONATHAN S
权利人:US NAVY
摘要:A method of making a molecularly imprinted porous structure makes use of a surfactant analog of the molecule to be imprinted that has the imprint molecule portion serving as the surfactant headgroup. The surfactant analog is allowed to self-assemble in a mixture to create at least one supramolecular structure having exposed imprint groups. The imprinted porous structure is formed by adding reactive monomers to the mixture and allowing the monomers to polymerize, with the supramolecular structure serving as a template. The resulting solid structure has a shape that is complementary to the shape of the supramolecular structure and has cavities that are the mirror image of the imprint group. Similarly, molecularly imprinted particles may be made by using the surfactant to create a water-in-oil microemulsion wherein the imprint groups are exposed to the water phase. When reactive monomers are allowed to polymerize in the water phase to form particles, the surface of the particles have cavities that are the mirror image of the imprint group.