CAS: 40610-41-1; (R)-2-Phenyl-2-Pivalamidoacetic Acid

该化合物是主要用于制药和化工工业的化合物,其特点是作为各种活性药物成分合成的中间体的作用,该化合物通常具有有机溶剂中中度溶解性和在标准实验室条件下的稳定性等特性,其分子结构可能包括有助于其反应和与其他化学物种互动的功能组;安全数据表表明,应当谨慎处理该物质,因为如果摄取或吸入,它可能会对健康造成危害.此外,适当的储存条件对于保持其完整性和防止降解至关重要.总的来说,IMp.K(EP)是化学合成中有价值的建筑块,它突出了中间体在药化学中复杂分子的开发中的重要性.

英文名称(R)-2-Phenyl-2-Pivalamidoacetic Acid
中文名称氨苄西林杂质K
IUPAC名称(R)-2-phenyl-2-pivalamidoacetic acid
其它别名Imp. K (Ep); Ampicillin Ep Impurity K; Ampicillin Impurity K; (2R)-2-(2,2-Dimethylpropanoylamino)-2-Phenylacetic Acid; Ampicillin Impurity 11（ampicillin Ep Impurity K）; Benzeneacetic Acid, α-[(2,2-Dimethyl-1-Oxopropyl)Amino]-, (R)- (9Ci); Ampicillin Sodium Impurity K; Ampicillin Sodium Ep Impurity K
CAS编号40610-41-1
MFCD编号:MFCD16380977
EINECS号:687-980-9
FDA UNII编号:G88PE39NQO
分子式:C13H17NO3
分子量:235.28
产品CID: 1419888
产品分类分析化学 → 标准品 → 药典标准品和杂质标准品

相似结构搜索
InChIKey: UYMYKMRRCXEIRJ-SNVBAGLBSA-N
InChI=1S/C13H17NO3/c1-13(2,3)12(17)14-10(11(15)16)9-7-5-4-6-8-9/h4-8,10H,1-3H3,(H,14,17)(H,15,16)/t10-/m1/s1…
计算化学: 氢键受体数3.0氢键供体数2.0可旋转键数4.0

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H302-H312-H332
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P330-P362-P403+P233-P501
危险品标志Xi
安全声明H303+H313+H333

上下游产品

(R)-phenylglycine pivaloyl chloride phenylglycin acrylic acid methyl ester

合成工艺路线路线简述

左旋苯甘氨酸,三甲基乙酰氯置于sodium Hydroxide,盐酸体系中,用水作为反应溶剂,以34%的收率获得产物氨苄西林钠杂质k
参考文献:Synthesis And Enantiomeric Recognition Studies Of A Novel 5,5-Dioxophenothiazine-1,9 Bis(Thiourea) Containing Glucopyranosyl Groups
标题:Synthesis And Enantiomeric Recognition Studies Of A Novel 5,5-Dioxophenothiazine-1,9 Bis(Thiourea) Containing Glucopyranosyl Groups
摘要:A Novel Optically Active 5,5-Dioxophenothiazine-1,9 Bis(Thiourea) Containing Glucopyranosyl Groups Was Synthesized And Its Enantiomeric Recognition Properties Were Examined Towards The Enantiomers Of Tetrabutylammonium Salts Of Chiral Alpha-Hydroxy And N-Protected Alpha-Amino Acids Using Uv-Vis Spectroscopy. (C) 2012 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Tetasy.2012.11.020