CAS: 85233-19-8; 2,2',2'',2'''-(((Ethane-1,2-Diylbis(Oxy))Bis(2,1-Phenylene))Bis(Azanetriyl))Tetraacetic Acid

上下游产品

CAS号51661-19-9 1,2-双(2-硝基苯氧基)乙烷 | CAS号824-39-5 邻硝基苯酚钠 | CAS号88-75-5 邻硝基苯酚 | CAS号73630-07-6 1,2-双(2-氨基苯氧基)乙... | CAS号52411-34-4 2,2'-二氨基乙二醇二苯醚

Sodium O-Nitrophenate置于palladium On Activated Charcoal 氢氧化钾,Sodium Iodide体系中,用 乙醇,N,N-二甲基甲酰胺,乙腈 作为反应溶剂,化学反应 22.0H,反应生成 1,2-双(2-氨基苯氧基)-乙烷-N,N,N`,N`-四乙酸
参考文献:Heilporn,S.; Broeders,F.; Daloze,D.,Bulletin Des Societes Chimiques Belges,1994,Vol. 103,# 7-8,P. 309-320
标题:Heilporn,S.; Broeders,F.; Daloze,D.,Bulletin Des Societes Chimiques Belges,1994,Vol. 103,# 7-8,P. 309-320

专利信息

专利号:US-12421534-B2
优先权日:2021-11-10
标 题 :Engineered enzymes and method for the synthesis of diverse tyrosine analogs
发明人：ALMHJELL PATRICK J; ARNOLD FRANCES H
权利人:CALIFORNIA INST OF TECHN
摘要:Provided herein is an engineered tryptophan synthase β-subunit (TrpB) that catalyzes the synthesis of tyrosine, tyrosine analogs, or salts thereof. Also provided herein are methods for preparing tyrosine, tyrosine analogs, or a salt thereof using the engineered TrpB described herein.

专利号:US-12024731-B2
优先权日:2017-05-03
标 题 :Methods and enzyme catalysts for the synthesis of non-canonical amino acids
发明人：BOVILLE CHRISTINA E; BRINKMANN-CHEN SABINE; BULLER ANDREW R; ROMNEY DAVID K; PRIER CHRISTOPHER K; KOCH PHILIPP; SCHEELE REMKES A
权利人:CALIFORNIA INST OF TECHN
摘要:The present disclosure provides methods for preparing β-substituted tryptophan compounds. The methods include: combining i) an unsubstituted indole or a substituted indole, ii) a β-substituted serine, and iii) a tryptophan synthase β-subunit (i.e., a TrpB); and maintaining the resulting mixture under conditions sufficient to form the β-substituted tryptophan. The TrpB contains at least one amino acid mutation which promotes formation of an amino-acrylate intermediate. New TrpB variants and new β-substituted tryptophan analogs are also described.

专利号:US-10829792-B2
优先权日:2017-03-21
标 题 :Biocatalytic synthesis of strained carbocycles
发明人：CHEN KAI; HUANG XIONGYI; KAN S B JENNIFER
权利人:CALIFORNIA INST OF TECHN
摘要:Provided herein are methods for producing products containing strained carbocycles, such as cyclopropene moieties and/or bicyclobutane moieties. The methods include combining an alkyne and a carbene precursor in the presence of a heme protein, e.g., a cytochrome P450, under conditions sufficient to form the strained carbocycle. Reaction mixtures for producing strained carbocycles are also described, as well as whole-cell catalysts comprising heme proteins and variants thereof for forming cyclopropenes, bicyclobutanes, and related products.

专利号:US-2023002805-A1
优先权日:2021-06-25
标 题 :Use of organic cationic compounds to accelerate nucleic acid hybridization, synthesis, and amplification
发明人：RABBANI ELAZAR; COLEMAN JACK
权利人:ENZO BIOCHEM INC
摘要:The invention provides methods for accelerated synthesis of nucleic acids, and related compositions which involve the use of organic amines in the nucleic acid synthesis reaction mixture. The invention also provides methods for reducing processing steps associated with nucleic acid synthesis. The invention further provides methods for screening compounds that have positive benefits on the synthesis of nucleic acids.

专利号:US-2019323050-A1
优先权日:2016-12-21
标题 :Modulation of Enzymatic Polynucleotide Synthesis Using Chelated Divalent Cations
发明人：GRISWOLD JR KETTNER JOHN FREDERICK; LEE HOWON; CHURCH GEORGE M
权利人:HARVARD COLLEGE
摘要:Methods and apparatus of modulating polynucleotide synthesis are provided. The methods include delivering reagents comprising enzymes, nucleotides and ions to oligonucleotide primers wherein the reagents catalyze incorporation of the nucleotides to 3′ ends of the oligonucleotide primers, and modulating incorporation of the nucleotides to the 3′ ends of the oligonucleotide primers. Polynucleotide synthesis is modulated by modulating presence or absence of catalytic cation cofactors to provide sequence defined synthesis of polynucleotides. In certain embodiments, the polynucleotides encode information.

专利号:US-11851651-B2
优先权日:2017-06-19
标 题 :Automated methods for scalable, parallelized enzymatic biopolymer synthesis and modification using microfluidic devices
发明人：BANAL JAMES; BERLEANT JOSEPH DON; SHEPHERD TYSON; BATHE MARK
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:Methods for the automated template-free synthesis of user-defined sequence controlled biopolymers using microfluidic devices are described. The methods facilitate simultaneous synthesis of up to thousands of uniquely addressed biopolymers from the controlled movement and combination of regents as fluid droplets using microfluidic and EWOD-based systems. In some forms, biopolymers including nucleic acids, peptides, carbohydrates, and lipids are synthesized from step-wise assembly of building blocks based on a user-defined sequence of droplet movements. In some forms, the methods synthesize uniquely addressed nucleic acids of up to 1,000 nucleotides in length. Methods for adding, removing and changing barcodes on biopolymers are also provided. Biopolymers synthesized according to the methods, and libraries and databases thereof are also described. Modified biopolymers, including chemically modified nucleotides and biopolymers conjugated to other molecules are described.