CAS: 103068-41-3; 4-Fluororesorcinol

相似化合物

103068-40-2 367-12-4 75996-29-1

上下游产品

1,3-dimethoxy-4-fluorobenzene 2,6-dimethoxy-3-fluoroacetophenone recorcinol 1,3-Dimethoxybenzene 2-(2,7-difluoro-3,6-dihydroxy-9H-xanthen-9-yl)benzoic acid H-xanthen-9-yl)-9,10-diphenyl-anthracene-2-carboxylic acid3-(2,7-difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)-9,10-diphenyl-anthracene-2-carboxylic acid

间苯二甲醚置于三氟甲基次氟酸酯,氢溴酸体系中,用 1,1,2-三氯三氟乙烷(cfc-113),溶剂黄146 用作溶剂,化学反应 4.0H,反应生成4-氟间苯二酚
参考文献:Belanger,Patrice C.; Lau,C. K.; Williams,Haydn W. R.,Canadian Journal Of Chemistry,1988,Vol. 66,P. 1479-1482
标题:Belanger,Patrice C.; Lau,C. K.; Williams,Haydn W. R.,Canadian Journal Of Chemistry,1988,Vol. 66,P. 1479-1482

专利信息

专利号:US-6229055-B1
优先权日:1996-04-12
标题 :Synthesis of fluorinated xanthene derivatives
发明人：KLAUBERT DIETER H; GEE KYLE R
权利人:MOLECULAR PROBES INC
摘要:Facile syntheses for fluorinated resorcinol and aminophenol derivatives are provided that yield isomer-free products in good yield. These novel methods use generally available precursors and standard laboratory reagents and equipment to reproducibly produce these synthetically useful reagents in relatively large quantities. The resulting fluorinated resorcinols and aniinophenols possess utility in the preparation of fluorinated fluorescein and rhodol dyes.

专利号:US-2016223559-A1
优先权日:2015-02-02
标题:Tetrazine-containing compounds and synthetic methods thereof
发明人：DEVARAJ NEAL K; WU HAOXING; YANG JUN
权利人:UNIV CALIFORNIA
摘要:Described herein are tetrazine derivatives and efficient synthetic methods of synthesis thereof using elimination-Heck cascade reaction. Provided herein is the synthesis of conjugated tetrazines from the tetrazine derivatives. Also provided herein are methods of use of the conjugated tetrazines as fluorogenic probes for live-cell imaging.

专利号:US-7179906-B2
优先权日:1996-04-01
标 题 :Asymmetric benzoxanthene dyes
发明人：BENSON SCOTT C; MENCHEN STEVEN M; THEISEN PETER D; HENNESSEY KEVIN M; FURNISS VERGINE C; HAUSER JOAN D
权利人:APPLERA CORP
摘要:A class of asymmetric monobenzoxanthene compounds useful as fluorescent dyes are disclosed having the structure n nwherein Y 1 and Y 2 are individually hydroxyl, amino, imminium, or oxygen, R 1 –R 8 are hydrogen, fluorine, chlorine, alkyl, alkene, alkyne, sulfonate, amino, amido, nitrile, alkoxy, linking group, and combinations thereof, and R 9 is acetylene, alkane, alkene, cyano, substituted phenyl, and combinations thereof. The invention further includes novel intermediate compounds useful for the synthesis of asymmetric benzoxanthene compounds having the general structuren n nwhere substituents R 3 –R 7 correspond to like-referenced substituents in the structure of described above, and Y 2 is hydroxyl or amine. In another aspect, the invention includes methods for synthesizing the above dye compounds and intermediates. In yet another aspect, the present invention includes reagents labeled with the asymmetric benzoxanthene dye compounds, including deoxynucleotides, dideoxynucleotides, phosphoramidites, and polynucleotides. In an additional aspect, the invention includes methods utilizing such dye compounds and reagents including dideoxy polynucleotide sequencing and fragment analysis methods.

专利号:US-11807643-B2
优先权日:2020-07-16
标 题 :Fluorescent dyes
发明人：LUND KEVIN P; SERGUEEV DMITRI; GALL ALEXANDER
权利人:CEPHEID
摘要:Automated oligonucleotide synthesis-compatible fluorescent dye phosphoramidite compounds, solid supports, and labeled polynucleotides incorporating the compounds are provided. The compounds allow universal incorporation of the fluorescent label into any position of the polynucleotide.