108365-79-3 = 107-31-3 + 1809-02-5 + 16906-18-6 + 10027-72-2 + 80-63-7 反应条件:1.1 Reagents: Hydrochloric Acid Solvents: 1,1,2,2-Tetrachloroethane,Methanol-D 标题:About The Ozone Cleavage Of Chloroprene And Of 2-Chloro-3-Methyl-1,3-Butadiene In Methanol 作者:Griesbaum,Karl; Et Al 参考文献:Chemische Berichte 日期:1987 卷标:120(9) 页码:1573-80
甲醚置于氧气,Molybdenum(Vi) Oxide体系中,化学反应生成甲酸甲酯 参考文献:Effects Of The Moo3 Structure Of Mo-sn Catalysts On Dimethyl Ether Oxidation To Methyl Formate Under Mild Conditions 标题:Effects Of The Moo3 Structure Of Mo-sn Catalysts On Dimethyl Ether Oxidation To Methyl Formate Under Mild Conditions 摘要:Sn含量对moo3在moo3-Sno2催化剂中的结构的影响. Doi:10.1039/c4Gc01591F
专利信息
专利号:US-7527712-B2 优先权日:2002-07-23 标 题 :Method for the continuous purification by distillation of the solvent methanol, used in the synthesis of propylene oxide 发明人:BASSLER PETER; GOEBBEL HANS-GEORG; TELES JOAQUIM HENRIQUE; RUDOLF PETER 权利人:BASF AG 摘要:Process for the continuously operated purification by distillation of the methanol used as solvent in the synthesis of propylene oxide by reaction of a hydroperoxide with propylene, with the methoxypropanols being separated off simultaneously, wherein the solvent mixture obtained in the synthesis is separated in a dividing wall column into a low-boiling fraction including methanol, an intermediate-boiling fraction containing the methoxypropanols as azeotrope with water and a high-boiling fraction including water and propylene glycol.
专利号:US-2005252762-A1 优先权日:2002-07-23 标 题:Method for the continuous purification by distillation of methanol, used as a solvent in the synthesis of propylene oxide without coupling products, with the simultaneous isolation of the methoxy propanols 发明人:BASSLER PETER; GOBBEL HANS-GEORG; TELES JOAQUIM H; RUDOLF PETER 权利人:BASF AG 摘要:Continuously operated process for the purification by distillation of the methanol used as solvent in the synthesis of propylene oxide by reaction of a hydroperoxide with propylene, with the methoxypropanols, as azcotrope with water, and the low boilers and high boilers simultaneously being separated off, wherein the solvent mixture obtained in the synthesis is fractionated in a dividing wall column.
专利号:EP-0596485-B1 优先权日:1992-11-05 标题 :Electrochemical process for preparing alcoholates of alkaline metal and use thereof for regenaration of the catalyst in the synthesis of methylformat 发明人:SOBOTTA GEORG DR-ING; PAZDERSKI JURI ANTONOWITSCH PR; SKATSCHKO WLADIMIR PETROWITSCH; LEZJUK WASSILI WLADIMIROWITSCH; TAGAJEW OLEG ALEXEJEWITSCH DR 权利人:SALZGITTER ANLAGENBAU; SYNTHEZ BNII 摘要:The invention relates to a process for the electrochemical synthesis of alkali metal alcoholates (alkoxides) and/or for the regeneration of the catalyst from methyl formate synthesis from alcoholic solutions of salts of alkali metals in an electrolysis apparatus with an ion-selective membrane. The electrolysis is carried out in the presence of a defined quantity of a potassium salt or sodium salt of a perfluoroalkanesulphonic acid accompanied by the use of non-oxidisable anode material and with a membrane based on a sulphonated styrene-divinylbenzene copolymer. The process enables an increase in the selectivity of the procedure and a continuous synthesis.
专利号:US-5442065-A 优先权日:1993-09-09 标 题:Synthesis of tetrahydroquinoline enediyne core analogs of dynemicin 发明人:MAGNUS PHILIP D; ILIADIS THEODORE; EISENBEIS SHANE A; FAIRHURST ROBIN A 权利人:UNIV TEXAS 摘要:A process is described for the preparation of the core azobicyclo[7.3.1]tridecaenediyne moiety of the antitumor antibiotic dynemicin. The synthesis allows efficient production of the enediyne as a stable, compound in good yield from the adamantyl N-protected azabicyclo[7.3.1]tridecadiyne. The adamantyl protecting group is employed in the starting material, N-adamantyl dihydroquinoline or N-adamantyl 6-methoxy quinoline. Also disclosed are process for the synthesis of 3-hydroxy-6-methoxyquinoline and several N-substituted derivatives of azobicyclo[7.3.1]tridecaenediyne. Solid tumor and leukemia assays were performed on the analogs of dynemicin. The results suggest a method that these compounds will useful in treating certain types of leukemias and solid tumors. The disclosed synthesis provides a route to new dynemicin intermediates and analogs which will allow development of second and third generation dynemicins.
专利号:US-7910623-B2 优先权日:2005-07-22 标 题 :Synthesis of scabronines and analogues thereof 发明人:DANISHEFSKY SAMUEL J; WATERS STEPHEN P 权利人:SLOAN KETTERING INST CANCER 摘要:A novel synthesis of scabronines, which are related to a broader class of angularly fused tricyclic diterpenoids known as cyathanes, is provided. Scabronine G, its methyl ester derivative, and other analogs have been shown to have neurotrophic activity. Therefore, these compounds are particularly useful in treating neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Huntington's diseases, etc. The invention provides for the synthesis of scabronines as well as analogs thereof. Pharmaceutical compositions and method of using the inventive compounds are also provided.
专利号:EP-2644590-A1 优先权日:2012-03-30 标 题:Synthesis of 2-(3,4-difluorophenyl)cyclopropanamine derivatives and salts 权利人:LEK PHARMACEUTICALS 摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.