CAS: 2253-73-8; Isopropylisothiocyanate

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Methyl N,N-Dimethyl-N'-Propan-2-Ylcarbamimidothioate 以 二硫化碳 用作溶剂,化学反应生成异硫氰酸异丙酯
参考文献:Schaumann,E.; Kausch,E.,Justus Liebigs Annalen Der Chemie,1978,P. 1560-1567
标题:Schaumann,E.; Kausch,E.,Justus Liebigs Annalen Der Chemie,1978,P. 1560-1567

专利信息

专利号:US-3781324-A
优先权日:1969-11-03
标 题:Certain 6-trifluoromethylcytosines and thiocytosines,their synthesis,and their use in the synthesis of uracils and thiouracils
发明人：LUTZ A
权利人:AMERICAN CYANAMID CO
摘要:3-AMINO-2-SUBSTITUTED - 4,4,4 - TRIFLUORO-2-BUTENENITRILES ARE REACTED WITH ISOCYANATES OR ISOTHIOCYANATES IN THE PRESENCE OF AN INERT SOLVENT AND FROM 0.75 TO ABOUT 1.0 MOLE EQUIVALENTS OF STRONG BASE PER MOLE OF BUTENENITRILE TO PRODUCE THE NOVEL UREIDO BUTENENITRILES OF THE FORMULA: CF3-C(-NH-C(=X)-NH-R)=C(-HALO)-CN WHEREIN R IS ALKYL, ALKENYL, PHENYL, BENZYL AND SUBSTITUTED DERIVATIVES THEREOF AND X IS SULFUR OR OXYGEN. THE UREIDO BUTENENITRILE ARE TREATED WITH ADDITIONAL BASE TO PRODUCE NOVEL CYCLIC CYTOSINES OF THE FORMULA: 6-CF3,5-HALO,4-(HN=),3-R,2-(X=)-1,2,3,4-TETRAHYDRO- PYRIMIDINE WHEREIN R AND X ARE AS DEFINED ABOVE. THE CYTOSINES CAN BE PRODUCED DIRECTLY BY TREATING 3-AMINO-2-SUBSTITUTED4,4,4-TRIFLUORO-2-BUTENENITRILE WITH AT LEAST 1.0 MOLE EQUIVALENT OF BASE. THE NOVEL COMPOUNDS ARE USEFUL INTERMEDIATES IN THE PREPARATION OF HERBICIDAL URACILS AND THIOURACILS.

专利号:US-3635977-A
优先权日:1969-11-03
标 题 :Certain 6-trifluoromethylcytosines and thiocytosines their synthesis and their use in the synthesis of uracisls and thiouracil
发明人：LUTZ ALBERT WILLIAM
权利人:AMERICAN CYANAMID CO
摘要:3 - AMINO - 2 - SUBSTITUTED - 4,4,4 - TRIFLUORO - 2 - BUTENENITRILES ARE REACTED WITH ISCYANATES OR ISOTHIOCYANATES IN THE PRESENCE OF AN INERT SOLVENT AND FROM 0.75 TO ABOUT 1.0 MOLE EQUIVALENTS OF STRONG BASE PER MOLE OF BUTENENITRILE TO PRODUCE THE NOVEL UREIDO BUTENEITRILES OF THE FORMULA: NC-C(-HALO)=C (-CF3)-NH-C(=X)-NH-R PYRIMIDINE WHEREIN R IS ALKYL, ALKENYL, PHENYL, BENZYL AND SUBSITUTED DERIVATIVES THEREOF AND X IS SULFUR OR OXYGEN. THE UREIDO BUTENENITRILES ARE TREATED WITH ADDITIONAL BASE TO PRODUCE NOVEL CYCLIC CYTOSINES OF THE FORMULA; 2(=X),3-R,4-(=NH),5-(HALO-),6-(F3C-)-1,2,3,4-TETRAHYDRO WHEREIN R AND X ARE AS DEFINED ABOVE. THE CYTOSINES CAN BE PRODUCED DIRECTLY BY TREATING 3-AMINO-2-SUBSITUTED4,4,4-TRIFLUORO-2-BUTENENTRILE WITH AT LEAST 1.0 MOLE EQUIVLAENTS OF BASE. THE NOVEL COMPOUNDS ARE USEFUL INTERMEDIATES IN THE PREPARATION OF HERBICIDAL URACILS AND THIOURACILS.

专利号:US-5629394-A
优先权日:1992-12-17
标 题 :Direct synthesis by living cationic polymerization of nitrogen-containing polymers
发明人：CHERADAME HERVE M; CHEN FRANK J; STANAT JON E R; NGUYEN HUNG A; TABAR BEHROOZ R
权利人:EXXON CHEMICAL PATENTS INC
摘要:A method is provided for the direct synthesis by living cationic polymerization of novel polymeric materials functionalized with desirable nitrogen-containing functional groups such as terminal azido, cyano, carbonylamino, cyanato, thiocyanato or thiocarbonylamino groups. Polymerization and functionalization occur in a substantially simultaneous manner. All necessary reactants for the functionalization are present when polymerization is initiated. The nitrogen-containing functional group is provided as a part of a molecule having a release moiety which is preferably resonance stabilized or a tertiary alkyl type and which acts to aid the nitrogen-containing species in functioning as a leaving group.

专利号:US-9469850-B2
优先权日:2007-01-18
标 题 :Oligosaccharides comprising an aminooxy group and conjugates thereof
发明人：ZHU YUNXIANG; CHENG SENG H; JIANG CANWEN; AVILA LUIS Z
权利人:GENZYME CORP
摘要:The invention provides methods for the synthesis of oligosaccharides comprising an aminooxy group. The invention further provides oligosaccharides comprising an aminooxy group, methods for coupling oligosaccharides comprising an aminooxy group to glycoproteins, and oligosaccharide-protein conjugates. Also provided are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide-protein conjugate.

专利号:WO-2006043121-A1
优先权日:2004-10-20
标 题:Oxazolidinone derivatives as antimicrobials
发明人：MEHTA ANITA; DAS BISWAJIT; RUDRA SONALI; YADAV AJAY SINGH; KUMARI SANGITA; SALMAN MOHAMMAD; RATTAN ASHOK
权利人:RANBAXY LAB LTD; MEHTA ANITA; DAS BISWAJIT; RUDRA SONALI; YADAV AJAY SINGH; KUMARI SANGITA; SALMAN MOHAMMAD; RATTAN ASHOK
摘要:The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiple-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms such as Bacterioides spp. and Clostridia spp. species, and acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.

专利号:CN-117659327-A
优先权日:2023-12-13
标题 :Method for catalytic synthesis of novel polyurethane elastomer and application thereof