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专利信息

专利号:EP-2784055-A1
优先权日:2013-03-28
标 题 :Fluoroform synthesis and uses thereof in the preparation of trifluoromethylated compounds
发明人：JUBAULT PHILIPPE; PANNECOUCKE XAVIER; IVASHKIN PAVEL
权利人:INST NAT DES SCIENCES APPLIQUÉES DE ROUEN INSA; CENTRE NAT RECH SCIENT
摘要:The present invention relates to a process to prepare fluoroform (CHF 3 ), notably radio labelled with fluorine-18, comprising a substitution reaction between CHAF 2 and a fluoride salt, nwherein A representsn norn nas well as a process to prepare a composition comprising copper-based or silver-based trifluoromethylated reagents using notably the fluoroform thus prepared and the use of a composition comprising copper-based trifluoromethylated reagents or a mixture comprising a copper salt and a composition comprising silver-based trifluoromethylated reagents as a trifluoromethylating agent, notably radio labelled with fluorine-18.