CAS: 5117-19-1; 3,6,9,12,15,18,21-Heptaoxatricosane-1,23-Diol

该化合物是一个聚醚化合物,其特点是其长的湿性苯乙烯甘醇链;一种无色,粘稠液体,在水和许多有机溶剂中溶解,在各种应用中有用;该物质具有较高的分子重量,有助于其作为表面活化剂和乳化剂的特性;八乙烷甘醇具有低毒性,并经常用于个人护理产品,药品和润滑剂的配制;其形成氢联结的能力增强了其溶解性以及与其他分子的相互作用;此外,该物质可以作为塑料剂,用于聚合物的生产;该化合物的结构使其能够有效地减少表面的紧张,使其在工业过程中具有价值;

结构式图片

相似化合物

25990-96-9 886469-23-4 1611489-00-9

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CAS号112-60-7 三缩四乙二醇 | CAS号37860-51-8 四乙二醇二对甲苯磺酸酯 | CAS号86259-87-2 四甘醇单苄醚 | CAS号105891-51-8 2-[2-[2-(2-chlo... | CAS号88099-82-5 2-methyl-1,3,6,... | CAS号2615-15-8 六乙二醇 | CAS号33089-37-1 24-冠8-醚 | CAS号71092-61-0 48-Crown-16 | CAS号352439-36-2 O-(2-叠氮乙基)七聚乙二醇 | CAS号22732-77-0 1-[2-[2-[2-[2-[... | CAS号6790-09-6 十二甘醇 | CAS号88099-82-5 2-methyl-1,3,6,... | CAS号57436-38-1 Tos-PEG8-Tos | CAS号54797-77-2 1-[2-[2-(2-chlo...

合成工艺路线路线简述

    六甘醇置于lithium Aluminium Tetrahydride,Sodium Hydride体系中,用 四氢呋喃 作为反应溶剂,化学反应 20.0H,反应生成 八乙二醇
    参考文献:单分散低聚(乙二醇)的便捷合成
    标题:单分散低聚(乙二醇)的便捷合成
    摘要:描述了一种在相转移条件下合成低聚(乙二醇)的简便方法.oligo(Ethylene Glycols) (X = 7-12) 通过容易获得的乙二醇二甲苯磺酸酯的模块化双向延伸以优异的收率和高纯度获得.
    DOI:10.1055/s-2004-816007

    海关参考信息

    专利信息


    专利号:US-11945838-B2
    优先权日:2018-12-20
    标 题:Method for synthesis of protein amphiphiles
    发明人:BRITTO Sandanaraj Selvaraj; REDDY Mullapudi Mohan
    权利人:INDIAN INSTITUTE OF SCIENCE EDUCATION AND RES
    摘要:The present invention discloses a novel cost effective method for synthesis of protein/peptide amphiphiles irrespective of functional and structural classification of proteins useful in designing a vaccine candidate from antigenic protein. The protein modification of the present invention is universal and hence any protein/peptide can be converted into amphiphilic proteins/peptides.

    专利号:WO-2023102600-A1
    优先权日:2021-12-06
    标题:Synthesis of amphiphilic block copolymers and polymeric nanofibers produced therefrom
    发明人:ZETTERLUND PER B; ISHIZUKA FUMI; KIM HYUN JIN; CHATANI SHUNSUKE; NIINO HIROSHI
    权利人:NEWSOUTH INNOVATIONS PTY LTD
    摘要:The present disclosure relates to the field of synthesis of block copolymers, and polymeric nanofibers having a core-shell morphology produced therefrom. The present disclosure relates to the field of synthesis of block copolymers where one block is more hydrophobic than the other block and is a different composition. The disclosure also relates to uses of these polymeric nanofibers in various applications, such as reinforcing a polymeric matrix and for coatings applications.

    专利号:US-5192520-A
    优先权日:1989-09-13
    标题:Synthesis of aluminosilicate zeolites of faujasite structure
    发明人:DELPRATO FRANCOIS; GUTH JEAN-LOUIS; HOFFNER FREDERIQUE; ZIVKOV CATHERINE
    权利人:ELF AQUITAINE
    摘要:PCT No. PCT/FR90/00599 Sec. 371 Date May 10, 1991 Sec. 102(e) Date May 10, 1991 PCT Filed Sep. 11, 1990 PCT Pub. No. WO91/04226 PCT Pub. Date Apr. 4, 1991.An aluminosilicate gel containing an ST structuring agent whose composition is suitable for crystallization into a zeolite of the faujasite structural family is prepared. The gel then undergoes crystallization in order to form a zeolite precursor which consists of the zeolite containing the ST structuring agent in its cavities and channels, the zeolite being produced through the calcination of the precursor. The ST structuring agent consists of at least one compound from the alkylene polyoxides of formula (1) (I) in which R and R', identical or different, each represents H or an alkyl radical in C1 to C4, X designates H or OH, m is equal to 2 or 3 and can differ from one pattern to another, and n is a number from 1 to 12. The zeolites thus obtained have a Si:Al ratio which is greater than 1 and which can go beyond 3, and show a cubic symmetry. The zeolites can be used, directly or after cation exchange, as adsorbants or as catalyst constituents.

    专利号:US-5393511-A
    优先权日:1988-10-10
    标题 :Synthesis of zeolites of faujasite structure
    发明人:DELPRATO FRANCOIS; GUTH JEAN-LOUIS; ANGLEROT DIDIER; ZIVKOV CATHERINE
    权利人:ELF AQUITAINE
    摘要:A process is provided for the preparation of zeolites belonging to the faujasite structural class and exhibiting a Si:Al ratio higher than 1 in which a reaction mixture is first produced, which has a pH higher than 10 and contains water, a source of tetravalent silicon, a source of trivalent aluminum, a source of hydroxide ions in the form of a strong inorganic or organic base and a structuring agent ST so as to produce an aluminosilicate gel having the desired composition to permit its crystallization into a compound of the faujasite structural class. The gel obtained is kept at a temperature, pressure and for a sufficient period to effect the crystallization of the gel into a precursor of the zeolite consisting of the zeolite trapping the structuring agent ST in its cavities and the precursor is then subjected to a calcination to destroy the structuring agent and to produce the zeolite. The structuring agent ST consists of at least one compound belonging to the group formed by the carbon-containing macrorings and macropolyrings which contain in the rings heteroatoms chosen from oxygen, nitrogen, silicon and sulphur, and which contain 10 to 24 atoms per ring. Precursors of the zeolites are also provided.

    专利号:US-5098686-A
    优先权日:1988-10-10
    标题 :Synthesis of zeolites of faujasite structure
    发明人:DELPRATO FRANCOIS; GUTH JEAN-LOUIS; ANGLEROT DIDIER; ZIVKOV CATHERINE
    权利人:ELF AQUITAINE
    摘要:PCT No. PCT/FR89/00522 Sec. 371 Date Jun. 8, 1990 Sec. 102(e) Date Jun. 8, 1990 PCT Filed Oct. 10, 1989 PCT Pub. No. WO90/03944 PCT Pub. Date Apr. 19, 1990.A process is provided for the preparation of zeolites belonging to the faujasite structural class and exhibiting a Si:Al ratio higher than 1 in which a reaction mixture is first produced which has a pH higher than 10 and contains water, a source of tetravalent silicon, a source of trivalent aluminum, a source of hydroxide ions in the form of a strong inorganic or orgnaic base and a structuring agent ST so as to produce an aluminosilicate gel having the desired composition to permit its crystallization into a compound of the faujasite structural class. The gel obtained is kept at a temperature, pressure and for a sufficient period to effect the crystallization of the gel into a precursor of the zeolite consisting of the zeolite trapping the structuring agent ST in its cavities and the precursor is then subjected to a calcination to destroy the structuring agent and to produce the zeolite. The structuring agent ST consists of at least one compound belonging to the group formed by the carbon-containing macrorings and macropolyrings which contain in the rings, heteroatoms chosen from oxygen, nitrogen, silicon and sulphur, and which contain 10 to 24 atoms per ring. Precursors of the zeolites are also provided.

    专利号:US-2023364251-A1
    优先权日:2020-08-06
    标 题:Methods for the synthesis of protein-drug conjugates
    发明人:BORCHARDT ALLEN; HUGHES ROBERT MICHAEL
    权利人:CIDARA THERAPEUTICS INC
    摘要:The present invention relates to intermediates and methods for synthesizing protein-drug conjugates that can be used for the treatment of diseases and related conditions.
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    主要参考文献


    1: Brown A, Patel S, Ward C, Lorenz A, Ortiz M, DuRoss A, Wieghardt F, Esch A, Otten EG, Heiser LM, Korolchuk VI, Sun C, Sarkar S, Sahay G. PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder. Sci Rep. 2016 Aug 30;6:31750. doi: 10.1038/srep31750.
    2: Saifer MG, Williams LD, Sobczyk MA, Michaels SJ, Sherman MR. Selectivity of binding of PEGs and PEG-like oligomers to anti-PEG antibodies induced by methoxyPEG-proteins. Mol Immunol. 2014 Feb;57(2):236-46. doi: 10.1016/j.molimm.2013.07.014. Epub 2013 Nov 5. doi: 10.1517/17425247.2012.720969. Epub 2012 Aug 30.

    合成参考文献


    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
    参考文献:10.4049/jimmunol.2000756
    摘要:Man S, Redman JE, Cross DL, Cole DK, Can I, Davies B, Hashimdeen SS, Reid R, Llewellyn-Lacey S, Miners KL, Ladell K, Lissina A, Brown PE, Wooldridge L, Price DA, Rizkallah PJ. Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells. J Immunol. 2021 Aug 15;207(4):1009–17.
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