CAS: 7651-02-7; N-(3-(Dimethylamino)Propyl)Stearamide

相似化合物

45267-19-4 3179-80-4 53201-66-4

上下游产品

CAS号109-55-7 3-二甲氨基丙胺 | CAS号57-11-4 硬脂酸 | CAS号112-61-8 硬脂酸甲酯 | CAS号110-95-2 四甲基丙二胺 | CAS号112-76-5 十八碳酰氯 | CAS号20284-67-7 dimethyl(3-stea... | CAS号88097-26-1 2-heptadecyl-1,...

N,N-二甲基-1,3-二氨基丙烷,棕榈酸 以 甲苯 作为反应溶剂,化学反应 48.0H,以61%的收率获得产物n-[3-(二甲基氨基)丙基]十八烷酰胺
参考文献:基于吡ido醇和脂肪酸的新型季铵化合物的设计,合成,抗菌活性和毒性
标题:基于吡ido醇和脂肪酸的新型季铵化合物的设计,合成,抗菌活性和毒性
摘要:设计了一系列基于季铵吡ido醇衍生物的43种新颖的"软抗菌剂",其中包括吡soft醇的六元缩醛和缩酮,它们通过可裂解的连接基部分(酰胺,酯)与脂肪羧酸的片段结合.九种化合物对革兰氏阳性和革兰氏阴性细菌菌株具有体外有望的抗菌活性,其mic值可与参考防腐剂miramistin,苯扎氯铵和氯己定相比.在各种临床分离株上,先导化合物6I和12A表现出与苯扎氯铵相当的抗菌活性,但比miramistin高.此外,6I和12A能够杀死嵌入单物种和双物种生物膜基质中的细菌.用6I和12A处理细菌细胞会导致膜快速去极化,表明该膜是化合物的明显分子靶标.6I和12A在sos-Chromotest和ames试验中均无致突变性,并且在小鼠急性口服(ld 50 > 2000 Mg / Kg)和经皮给药(ld 50 > 2500 Mg / Kg)时体内无毒.综上所述,我们的数据可以表明所描述的活性化合物是新抗菌剂开发的有希望的起点.
DOI:10.1016/j.Ejmech.2020.113100

专利信息

专利号:US-2023111600-A1
优先权日:2019-12-17
标题 :Polymeric fatty acid compounds for the treatment of fibrous amino acid-based substrates, especially hair
发明人：WAGNER ROLAND; STREICHER KATHARINA; ROHMANN LAURA; WENSKE CHRISTIAN; HAVELI SHRUTISAGAR DATTATRAYA
权利人:MOMENTIVE PERFORMANCE MAT GMBH
摘要:The present invention is directed at mono-, di- or polyquaternary ammonium compounds of the formula (I) wherein x is 1 to 50, and F can be the same or different and is represented by the general formula (II) wherein at least one of the optionally substituted and optionally functional-group-containing hydrocarbon radicals R 1 , R 2 , R 3 , R 4 or R 5 contains at least one estolide moiety comprising two or more ester or amide moieties. The invention also relates to a process for the synthesis of such compounds, the use of the compounds in cosmetic formulations for skin and hair care, cosmetic compositions for the treatment of fibers, and compositions containing one or more of the compounds for the treatment of hair.

专利号:EP-1239813-B1
优先权日:1999-12-23
标题:Extract of blue-green alga spirulina and the use thereof in cosmetic skin-care and body care agents
发明人：SCHLOTMANN KORDULA; WALDMANN-LAUE MARIANNE; JASSOY CLAUDIA; KAETEN MELANIE; KOEHLER EVA-MARIA; PULZ OTTO; KURTH ELKE
权利人:HENKEL KGAA
摘要:The invention relates to an aqueous or aqueous-alcoholic extract of the blue-green algal taxon Spirulina, characterized in that it contains at least 10 wt. % magnesium in relation to the dry weight of said extract. The inventive blue-green alga extract is an efficacious component for stimulating intracellular synthesis of ATP and matrix proteins and differentiation of keratinozytes. The blue-green alga extract is used in topical preparations for cleaning and cosmetic care of the skin and hair, in addition to the production of agents for dermatological treatment of the skin.

专利号:WO-2008028772-A1
优先权日:2006-09-06
标 题:Bioquinones for stimulating keratin synthesis
发明人：GIESEN MELANIE; SCHULZE ZUR WIESCHE ERIK; POPPE ELISABETH; WELSS THOMAS
权利人:HENKEL KGAA; GIESEN MELANIE; SCHULZE ZUR WIESCHE ERIK; POPPE ELISABETH; WELSS THOMAS
摘要:The present invention relates to the cosmetic use of one or more bioquinones for combating age-related changes in the hair follicles, for the promotion of keratin synthesis in the hair, and for positively influencing the structure of the hair. The invention further relates to a cosmetic method for combating age-related changes in the hair follicle, and to a method for stimulating keratin synthesis in hair.

专利号:WO-2024108286-A1
优先权日:2022-11-23
标 题 :Cosmetic composition for inducing melanin synthesis in an individual or animal; production process; cosmetic method and use
发明人：VIDAL MAGALHÃES WAGNER; BUENO DE CAMARGO JUNIOR FLÃ?VIO; ROBERTO ROSSAN MARCOS; THOMAZ CAMILO ANDREW
权利人:CHEMYUNION LTDA
摘要:The present invention describes a novel composition for inducing melanin synthesis in an individual or animal, as well as the use thereof to prevent and/or reverse the process of greying of the hair.

专利号:US-8431523-B2
优先权日:2006-06-01
标题:Oligomeric biosurfactants in dermatocosmetic compositions
发明人：OWEN DONALD R; FAN LILI
权利人:OWEN DONALD R; FAN LILI
摘要:Oligomeric acylated biosurfactants (“OABsâ€?) having low critical micelle concentrations of from about 1.0 ppm to about 200 ppm, preferably less than about 50 ppm, in an aqueous solution of Minimal Essential Media that can lower the surface tension in the aqueous MEM environment to less than about 50 dynes/cm 2 and have the ability to increase metabolic soluble proteins and/or increase synthesis of extracellular skin matrix proteins and/or increase rates of cell turnover while at the same time exhibiting comparatively low toxicity—preferably, an LD 50 of greater 200 ppm in 37 year-old female fibroblast cells. Another aspect of the present invention is directed to the use of OABs in formulations that are topically-applied, by which is meant the formulation is placed in direct contact with the skin, hair and nails as well as mucosa of the eyes, ears, nose, mouth, anus and vagina.

专利号:WO-2008028776-A1
优先权日:2006-09-06
标题 :Agents containing bioquinones and specific emulsifiers
发明人：SCHULZE ZUR WIESCHE ERIK; SCHEUNEMANN VOLKER; POPPE ELISABETH; WELSS THOMAS; GIESEN MELANIE
权利人:HENKEL KGAA; SCHULZE ZUR WIESCHE ERIK; SCHEUNEMANN VOLKER; POPPE ELISABETH; WELSS THOMAS; GIESEN MELANIE
摘要:The invention relates to cosmetic agents, in particular hair treatment agents, containing at least one specific emulsifier and at least one bioquinone. Treating the hair with said agents activates the keratin synthesis of hair keratin that declines with age.